This invention involves a full-automatic peptide synthesizer, including a CPU system, a GMP software operating system, a liquid control system, a gas control system, a materials input system, a reactor system, a limitless speed-regulating stirring system, a personal safety system, a reaction efficiency automatic feedback system, a fault alarm system, and a solution circulatory system. The invention has the advantages of higher synthesis efficiency of peptide, better product quality, shorter development cycles, lower production cost, and more convenient and safe operation. The invention is also consistent with the strict requirements of FDA on GMP production, meets a variety of synthetic peptide research and production requirements on the whole, and can be widely applied to basic research, peptide drugs, health, beauty, food, polymer materials, fine chemicals, organic synthesis, etc.