8 results about "Bromoacetonitrile" patented technology

This invention discloses a cyano-functionalized polyacrylic acid-based composite solid electrolyte material and its preparation method and application, belonging to the field of lithium battery technology. The method includes the following steps: (1) adding TMG, bromoacetonitrile, and bromopropylene to polyacrylic acid for catalytic esterification to obtain PAA-g-(CN / Vinyl); (2) mixing the PAA-g-(CN / Vinyl) with a photoinitiator and a lithium salt to obtain a polymer composite electrolyte precursor solution, followed by curing and crosslinking to obtain the cyano-functionalized polyacrylic acid-based composite solid electrolyte material. Starting from molecular design, this invention forms an integrated high-performance solid electrolyte system through a one-step controllable esterification reaction and subsequent composite curing, providing an innovative electrolyte solution for the development of safe, high-energy-density solid-state batteries.

The invention discloses a metal nitrogen heterocyclic carbene covalent organic framework catalyst and a preparation method and application thereof. The catalyst contains a nitrogen heterocyclic carbene covalent organic framework structure connected by a carbon-carbon double bond and is anchored with a metal species coordinated with the nitrogen heterocyclic carbene active site. The preparation method comprises: subjecting a triimidazolyl organic compound to a quaternization reaction with bromoacetonitrile to prepare a tricyanomethylimidazolium monomer; dissolving the tricyanomethylimidazolium monomer and a trialdehyde monomer in an organic solvent, and constructing an imidazolium covalent organic framework connected by a carbon-carbon double bond through a Knoevenagel condensation reaction; dissolving the imidazolium covalent organic framework in an organic solvent, deprotonating it under alkaline conditions to release the nitrogen heterocyclic carbene active site, and then reacting with a metal active component to prepare the metal nitrogen heterocyclic carbene covalent organic framework catalyst. The catalyst is used for catalyzing the synthesis of symmetric diselenides from elemental selenium and aryl iodine, and has wide applicability and high efficiency.

The present invention provides a preparation method of 6-chloroimidazo[1,2-b]pyridazine-3-carbonitrile, which includes (1) adding a polymerization inhibitor after dissolving 3-amino-6-chloropyridazine in DMF-DMA in a reactor to react and obtain an intermediate; (2) adding an organic solvent to the reactor, and the intermediate and bromoacetonitrile undergo a ring-closing reaction; after the reaction is completed, the pH of the material in the reactor is adjusted to neutral, and a crude product is obtained by cooling and crystallizing; (3) the crude product is recrystallized to obtain the 6-chloroimidazo[1,2-b]pyridazine-3-carbonitrile pure product. The preparation method of the present invention adds a polymerization inhibitor in the chain extension stage to promote the full reaction of bromoacetonitrile, avoid the appearance of an oily substance after the ring-closing reaction, and obtain a high-purity 6-chloroimidazo[1,2-b]pyridazine-3-carbonitrile pure product. The preparation method has a simple process flow, high yield, and the quality of the obtained pure product is good, with significant economic value and industrial application value.

The invention discloses a preparation method of an organic fluorescent compound with a piezochromic characteristic, and belongs to the technical field of fluorescent material preparation. The method comprises the following steps: S1, dissolving an initial compound in an acetonitrile solution, adding a first substance alkali, stirring, dropwise adding bromoacetonitrile to room temperature, and stirring overnight for reaction; s2, reserving filtrate after suction filtration, performing rotary evaporation to obtain a solid crude product, and performing column chromatography purification to obtain an intermediate compound; s3, dissolving the intermediate compound in absolute ethyl alcohol, adding a second substance, stirring until the second substance is stable, adding 4-diphenylaminobenzaldehyde, and stirring and reacting at room temperature; and S4, carrying out suction filtration after the reaction is finished, leaching a filter cake by using normal hexane, and drying to obtain the target compounds (E)-2-(4-chlorine-1H-pyrazole-1-yl)-3-(4-(diphenylamino) phenyl) acrylonitrile, (E)-2-(4-bromo-1H-pyrazole-1-yl)-3-(4-(diphenylamino) phenyl) acrylonitrile and (E)-2-(4-iodine-1H-pyrazole-1-yl)-3-(4-(diphenylamino) phenyl) acrylonitrile. The prepared compound has obvious piezochromic luminescent property, the raw materials are low in price, and the synthesis method is simple and easy to operate.

The invention discloses a metal N-heterocyclic carbene covalent organic framework catalyst and a preparation method and application thereof, the catalyst contains an N-heterocyclic carbene covalent organic framework structure connected through carbon-carbon double bonds, and metal species coordinated with N-heterocyclic carbene active sites are anchored; the preparation method comprises the following steps: carrying out quaternization reaction on a triimidazolyl organic compound and bromoacetonitrile to prepare a tricyanomethylimidazolium monomer; the preparation method comprises the following steps: dissolving a tricyanomethylimidazolium monomer and a trialdehyde monomer in an organic solvent, and constructing a carbon-carbon double bond connected midazolium covalent organic framework through a Knoevenagel condensation reaction; the preparation method comprises the following steps: dissolving an imidazolium covalent organic framework in an organic solvent, deprotonating under an alkaline condition to release N-heterocyclic carbene active sites, and reacting with a metal active component to prepare the metal N-heterocyclic carbene covalent organic framework catalyst. The catalyst is used for catalyzing elemental selenium and aryl iodide to synthesize symmetric diselenide, and is wide in applicability and efficient.

The application discloses a preparation method of a beta-ketonitrile derivative, which comprises the following steps: reacting alpha-bromoacetonitrile, aryl boronic acid, bis(triphenylphosphine)nickel chloride, 3,4,7,8-tetramethyl-1,10-phenanthroline, formic acid, acetic anhydride and sodium carbonate in C at 80 o for 20 hours, and after the reaction is completed, post-treatment is performed to obtain the beta-ketonitrile derivative. The preparation method uses alpha-bromoacetonitrile and aryl boronic acid as reactants, uses formic acid as a carbonyl source, has mild reaction conditions, simple operation, a wide functional group tolerance range of a substrate and high reaction efficiency. According to actual needs, a plurality of beta-ketonitrile derivatives can be synthesized, and the method is convenient to operate and wide in practicability.

A preparation method of trilaciclib and its intermediates belongs to the technical field of pharmaceutical chemistry. The purpose of the present invention is to provide a preparation method of trilaciclib and its intermediates that is environmentally friendly, low-cost, easy to operate, and suitable for industrial production. The main raw materials involved are 5-bromo-2,4-dichloropyrimidine, pyruvic acid, bromoacetonitrile, 1,5-dibromopentane, and 5-bromo-2-nitropyridine. Compared with the synthetic method reported in the literature that first introduces a spiro ring and then generates a pyrrolopyrimidine ring, the route of the present invention selects commercially available 5-bromo-2,4-dichloropyrimidine as the starting material, which is inexpensive and easily available, reducing the synthesis cost. Moreover, the reaction conditions of each step are mild, and the intermediates and end products are easy to purify and preserve. And this method uses new intermediates for synthetic research and has the potential for industrial production.

The invention relates to a high-energy-density seawater-based zinc-iodine battery electrolyte and a preparation method and application thereof, and belongs to the technical field of batteries. The high-energy-density seawater-based zinc-iodine battery electrolyte comprises an additive, seawater and zinc salt, and the additive is bromoacetonitrile. The electrolyte can generate three pairs of redox peaks in the charging and discharging process, redox of iodine valence state # imgabs 0 # and redox of bromine valence state # imgabs 1 # can be excited at the same time, six-electron transfer of halogen compounds in the zinc-iodine battery is achieved, and the battery capacity is remarkably improved. On one hand, the energy density of the battery is increased to 3 times (633mAh g <-1 >) of an initial value, and the battery has ultrahigh electrochemical performance, and on the other hand, the zinc-iodine battery containing the electrolyte has the advantages of easiness in manufacturing and low cost, so that the zinc-iodine battery can better meet commercial requirements.