The invention discloses an operation switching adjusting device for heat exchangers and circulating pumps of a heat exchange station and a working method. The device comprises a control module, a heat exchange station water inlet manifold water temperature sensor, heat exchanger primary water outlet pipe water temperature sensors, heat exchanger primary water inlet pipe electric control valves, heat exchanger secondary water outlet pipe water temperature sensors, check valves, circulating pump frequency conversion speed regulators, a water distributor water temperature sensor, a water collector water temperature sensor, a water distributor and collector pressure difference sensor and heat exchanger secondary water return pipe electromagnetic valves. The logarithmic mean temperature difference is introduced to quantitatively describe the heat exchange capacity of the heat exchangers, and the logarithmic mean temperature difference of the heat exchangers is used as a criterion when the heat exchangers are increased or decreased. By taking the opening degree of an electric control valve, the frequency of the circulating pumps, the water supply temperature, the pressure difference and the keeping time of the parameters as criteria, the equipment operation switching working method of the heat exchange station with two typical structures of 'first series connection and then parallel connection' and 'first parallel connection and then series connection' of the heat exchangers and the circulating pumps is provided, and the heat supply amount adjusting range of the heat exchange station can be effectively widened.