The present invention discloses a Chinese medicine composition for preventing and curing mammary cancer and its preparation method. Said Chinese medicine composition comprises 8 Chinese medicinal materials of peristrophe japonica, gynura segetum and others, and has efficiency of nourishing liver and kidney, supplementing qi and activating blood, resolving the stasis and relaxing vein. The preparation method thereof comprises the following steps: weighing each material according to a formula ratio, crushing the peristrophe japonica and formula amount of Chinese angelica, and safflower, sieving into powdery for standby; adding water into radix paeoniae rubrathe, gynura segetum, and asparagi radix and dococting for twice, condensing, adding alcohol for deposition, recovering the alcohol, condensing into extract for standby, adding the alcohol into unripe bitter orange and Radix Astragali and refluxing twice, filtering, condensing into the extract for standby; mixing the two condensed extracts, heating and adding the standby peristrophe japonica, Chinese angelica, and safflower drug powder and mixing, drying, sieving, granulating and preparating into the capsule. The invention adopts oral delivery, has convenient usage, good taste, and low cost. Compared with the same kind of the Westen medicine, the invention has advantages of reasonable formula, strict process, obviously curative effect, no toxic and side effect, easy acceptable for the sufferers, and suitable for long-term administration and so on, and provides the medicine composition with good effect for preventing and curing the mammary cancer.