The invention provides a production method of an organic fertilizer with cow dung as the main material. The method comprises the following steps: preparing a mixture of cow dung and saw dust, visceral meal of animals, plant ash, humic acid, powdered rock phosphate, rice hulls, seaweed meal, shell powder, perlite, a corrosion promoter, fructus kochiae, pine needles, tripterygium wilfordii, radix stemonae, cinnamon, clove, garlic powder and bentonite; A. fermenting the raw materials; B. adding the bentonite into the substance obtained in the step A, stirring for 40-50min, and then, conveying the mixture to a turn sieve machine, and turning and sieving the mixture to obtain a fertilizer raw material for later use; C. preparing a liquid traditional Chinese medicine raw material; D. adding the liquid traditional Chinese medicine raw material and the garlic powder into the fertilizer raw material obtained after turning and sieving, wherein the weight ratio of the fertilizer raw material to the liquid traditional Chinese medicine raw material to the garlic powder is 40:1:1; and E. granulating the mixture by using a granulator, drying the obtained granules for 20-25min, then, discharging the granules from a drying cylinder, and next, naturally cooling for 1-2h, wherein the mixture is obtained in the step D. The organic fertilizer is simple in proportion, convenient to use, balanced in nutrition, strong in antibacterial ability, high in absorption rate, strong in lodging resistance capability and takes the cow dung as the main material, wherein organic matter content is relatively high.