43results about How to "Broaden raw material channels" patented technology

The invention discloses a cortex periplocae anti-tumor effective component extractive, which is prepared by the following steps of: crushing cortex periplocae; extracting under heating by utilizing water at 90-100 DEG C, concentrating an extracting solution, carrying out alcohol precipitation, centrifuging, removing sediment and concentrating under reduced pressure to remove ethanol to obtain an extracting solution; or extracting under heating by utilizing ethanol with the concentration of 40-95% in a water bath of 80 DEG C, cooling and centrifuging, and concentrating to remove ethanol to obtain an extracting solution; sequentially extracting the extracting solution by utilizing ethyl acetate and water saturated n-butyl alcohol; subjecting a n-butyl alcohol extracted part to silica gel column separation, wherein a diluting agent is dichloromethane-methanol with the different volume ratios; collecting a diluting solution with the volume ratio of dichloromethane to methanol of 10: 1; and recycling an organic solvent to obtain the cortex periplocae anti-tumor effective component extractive. According to the cortex periplocae anti-tumor effective component extractive disclosed by the invention, in an in-vitro cellular toxicity test, the part has the obvious effects of inhibiting U251 (glioma cells), HepG2 (hepatoma carcinoma cells), SGC (stomach carcinoma cells), mcf-7 (human breast cancer cells) and SCLC (small cell lung cancer cells), and can be used for preparing an anti-tumor medicine. The invention discloses a preparation method of the cortex periplocae anti-tumor effective component extractive.

The invention provides an effective part of Corydalis conspersa as well as a preparation method and an application of the effective part and belongs to the technical field of plant extracts. The effective part of the Corydalis conspersa is selected from one of an ethyl acetate extract of the Corydalis conspersa, an n-butyl alcohol extract of the Corydalis conspersa and an aqueous extraction extract of the Corydalis conspersa or a mixture of two or more of the extracts of the Corydalis conspersa in any mass ratio. The preparation method comprises steps as follows: the herb of the Corydalis conspersa is ground, an ethanol solution with volume percentage concentration being 65%-95% is added for reflux extraction, an obtained extracting solution is concentrated and dried, and extractum is obtained; distilled water is added to the extractum, the extractum is dispersed, an extractum dispersion liquid is obtained and is extracted with petroleum ether, ethyl acetate and n-butyl alcohol as solvents sequentially, and after solvents are volatilized, the ethyl acetate extract of the Corydalis conspersa and the n-butyl alcohol extract of the Corydalis conspersa are obtained; the extractum dispersion liquid after extraction is concentrated and dried, and the aqueous extraction extract of the Corydalis conspersa is obtained. According to the application of the effective part of the Corydalis conspersa in preparation of drugs for inhibiting CDC25 enzyme and HDAC1 enzyme, the effective part of the Corydalis conspersa can be used for preparing antitumor drugs.

The invention discloses a hypecoum leptocarpum effective part as well as a preparation method and application thereof, belonging to the technical field of plant extract. The hypecoum leptocarpum effective part is selected from one or mixture of over two of a hypecoum leptocarpum n-butyl alcohol part, a hypecoum leptocarpum water-phase extraction part and a hypecoum leptocarpum chloroform part in any mass ratio. The preparation method comprises the following steps: grinding the hypecoum leptocarpum, adding a 65-95% ethanol solution by mass and performing reflux extraction; concentrating and drying to obtain extract; adding distilled water into the extract for dispersion; sequentially extracting with petroleum ether, ethyl acetate and n-butyl alcohol; volatilizing to remove solvents to obtain the hypecoum leptocarpum n-butyl alcohol part; concentrating and drying the extract dispersion liquid after extraction to obtain the hypecoum leptocarpum water-phase extraction part; and adding a 2% hydrochloric acid aqueous solution by mass into the extract for extraction, adjusting the pH value to 9-10, extracting repeatedly with chloroform, and volatilizing to remove solvents to obtain the hypecoum leptocarpum chloroform part. The application of the hypecoum leptocarpum effective part disclosed by the invention in preparing medicines for inhibiting HDAC1 enzymes can be used for preparing anti-tumor medicines.

The invention discloses a shiitake mushroom-salmon caviar formula. The shiitake mushroom-salmon caviar formula is prepared from the following raw materials: salmon roes, shiitake mushrooms, perilla frutescens, fermented soya beans, laurel leaves, cloves, honey and cooking wine. The shiitake mushroom-salmon caviar formula is composed of natural food materials, so that the prepared shiitake mushroom-salmon caviar is healthy, health-caring and refreshing in taste. The caviar contains trace elements, mineral salt, protein, amino acid and recombinant essential fatty acid needed by the skin, so that the caviar is capable of effectively moistening and nourishing the skin, as well as ensuring the skin fine, smooth, bright and clean. The shiitake mushrooms contain the components, including polysaccharides, vitamin B1, vitamin B2, calcium, phosphorus, iron and so on; and the shiitake mushrooms have the functions of reducing cholesterol, resisting cancer and enhancing body immunity.

Provided is asalmon caviar formula. Salmon caviar is made from salmon roe, basil, ginger, hot pepper, cinnamon, cloves, garlic, Chinese prickly ash, honey and cooking wine, the salmon caviar formula consists of natural food materials through mixing, is healthy, preserves good health, has a fresh and cool taste, the salmon caviar containstrace elements, mineral salts, proteins, amino acids and essential restructured fatty acids required by the skin, can effectively moisturize the skin and can also make the skin tender, smooth and clean.

The invention discloses a hawthorn fruit salmon caviar formula. The hawthorn fruit salmon caviar formula is prepared via blending of salmon, hawthorn fruit, purple perilla, sesame, tsaoko amomum fruit, clove, honey, and cooking wine. The hawthorn fruit salmon caviar formula is prepared via blending of the above natural food materials, is good for health, and is refreshing in mouthfeel; caviar contains trace elements, mineral salts, protein, amino acids, and recombinant essential fatty acids needed by the skin, so that caviar is capable of nourishing the skin effectively, and smoothening and brightening the skin; hawthorn fruit contains maslinic acid, vitamin C, saccharides, carotene, fat, protein, starch, calcium, and iron, and is capable of reducing blood pressure and blood lipid, strengthening heart, and promoting digestion.

The invention discloses the effective parts of skyblue adonis and the preparation method and application thereof and belongs to the technical field of plant extract. The method comprises of the steps of selecting the mixture of one or more than two extracts from the petroleum ether part, ethyl acetate, normal butyl alcohol part and water phase extraction part of skyblue adonis. Crushing the skyblue adonis and adding 65%-95% (weight) ethanol solution for extraction, concentrating and drying the extracting solution to obtain the extract; adding distilled water for dispersion to obtain extract dispersion, then respectively using petroleum ether, ethyl acetate and normal butyl alcohol as the solvent to extract the extract dispersion, making the solvent volatilize to obtain the petroleum ether part, ethyl acetate, normal butyl alcohol part and water phase extraction part of skyblue adonis; concentrating and drying the extracted extract dispersion to obtain the water phase extraction part of skyblue adonis. The effective parts of skyblue adonis of the invention can be used to prepare drugs inhibiting HDAC1 enzyme, and prepare cancer resistant drugs.

The invention discloses an effective part of thick-stalk corydalis pallida and a preparation method and application of the effective part, and belongs to the technical field of plant extract. The effective part is selected from the mixture of one or two or more of a thick-stalk corydalis pallida ethyl acetate part, a thick-stalk corydalis pallida n-butyl alcohol part and a thick-stalk corydalis pallida water phase extraction part in any mass ratio. The preparation method comprises the steps that whole thick-stalk corydalis pallida is smashed, an ethanol solution with the volume percentage concentration of 65-95% is added for reflux extraction, and the obtained extracting solution is concentrated and dried to obtain extract; distilled water is added in the extract for dispersion, extract dispersing liquid is obtained, petroleum ether, ethyl acetate and n-butyl alcohol are used as solvents in sequence for extracting the extract dispersing liquid, a solvent is volatilized away, and the thick-stalk corydalis pallida ethyl acetate part and the thick-stalk corydalis pallida n-butyl alcohol part are obtained; the extracted extract dispersing liquid is concentrated and dried to obtain the thick-stalk corydalis pallida water phase extraction part. The effective part of the thick-stalk corydalis pallida is applied in preparation of medicine for inhibiting CDC25 enzyme and can be used for preparing anti-tumor medicine.

The invention discloses limonium franchetii antineoplastic active constituent extract and a preparation method and application thereof. According to the limonium franchetii antineoplastic active constituent extract, after alcohol extraction is carried out on limonium franchetii, four kinds of active extract including cyclohexane, ethyl acetate, n-butyl alcohol and water are obtained. The active extract of the limonium franchetii can restrain proliferation of various cancer cell strains, the restraining effect is remarkable especially for leukemia cells HL-60 and K562, breast cancer cells MCF-7, lung cancer cells A549, cervical cancer cells Hela, liver cancer cells HepG-2 and other tumor cell strains, the antineoplastic activity of the ethyl acetate extract is most obvious, the anticancer spectrum is wide, the limonium franchetii active extract has the effect of inducing differentiation of the leukemia cells HL-60, and therefore the limonium franchetii antineoplastic active constituent extract can be used for preparation and development of antineoplastic drugs and has important significance especially for treatment researches of leukemia.

Provided is a poria cocos and salmoncaviarrecipe. Poria cocos and salmoncaviar is made by deploying salmon roes, poria cocos, curry, sesame, amomum tsao-ko, clove, oyster sauce and cooking wine, the poria cocos and salmoncaviarrecipe adopts natural food materials for deploying, is healthy and health-care and has a fresh and cool taste, the salmoncaviar contains trace elements, mineral salts, proteins, amino acids and essential restructured fatty acids required by the skin, can effectively moisturize the skin, can also make the skin tender, bright and clean, and the poria cocos contains pachyman, pachymic acid, fatty acid, lecithin, adenine, protease and triterpene substances and also contains potassium, calcium, magnesium, phosphorus, iron, sulfur, silica minerals and other mineral substances.

The invention provides a method for preparing electro-fused mullite from bauxite under coal, which comprises the following steps: grading the bauxite under coal, and removing silt; obtaining + d-grade minerals, and carrying out iron removal and desulfurization on the + d-grade minerals by adopting an X-ray concentrating machine to obtain intermediate minerals; calcining the intermediate mineral to obtain bauxite clinker; the preparation method comprises the following steps: crushing bauxite clinker, adding auxiliary materials, and uniformly mixing to obtain a mixture; melting the mixture in an electric arc furnace at a high temperature, cooling and crystallizing, and then crushing, grading and deironing to obtain a mullite product. According to the method, the under-coal bauxite is adopted as the main raw material to produce the fused mullite, the content of mullite phases in the mullite product is 95% or above, the comprehensive utilization rate of under-coal aluminum resources and the added value of the product are increased, the channel of the mullite raw material is widened, and sustainable high-quality development of the refractory material industry is powerfully supported.

The invention provides a formula of goose liver-salmon caviar. The goose liver-salmon caviar is made by blending salmon roes, goose livers, perilla leaves, round cardamom fruit, amomum tsao-ko, clove, honey and cooking wine. The goose liver-salmon caviar is made by blending the natural food materials, is healthy, capable of keeping health and fresh and cool in mouthfeel, contains trace elements, mineral salt, protein, amino acid and recombinant basic fatty acid which are needed by the skin and not only can effectively moisten the skin and enable the skin to obtain nutrients but also has the effects of enabling the skin to be fine, smooth, bright and clean, the goose livers are one of animal livers and have typical nutrient ingredients of the animal livers, and the livers are important organs for storing nutrients and removing toxicity in animal bodies, contain rich nutrient substances and are good blood replenishing products.