The invention relates to a combined vertical comb-type weeding mechanism for crop seedlings with loose soil, which belongs to agricultural machinery. In the technical scheme, a transmission case is provided with a rear power output shaft and a front power output shaft in parallel, the rear power output shaft is provided with a driving sprocket and a driving cylindrical gear, the front power output shaft is provided with a driven cylindrical gear, the outer ends of the front power output shaft and the rear power output shaft are fixedly provided with a comb-type shaft with elastic comb teeth respectively through a flange coupling plate, a circular chute is arranged on outer side faces of the front wall and the back wall of the transmission case, a driven plate is arranged on the circular chute, a pin shaft is arranged on the driven plate, and the two ends of a connecting plate are fixedly connected with the comb-type shaft and the pin shaft respectively. The mechanism can make the elastic comb teeth on the comb-type shaft always maintain the upright state during the operation, has the advantages of novel and reasonable structure, stable insertion of the elastic comb teeth in the soil, high operating quality, high efficiency, low rate of injured seedlings and high adaptability, and can be widely applied in inter-tillage of soybeans, corns, beets, cereals, cotton and other crops.