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35 results about "Cyclohexaneacetic acid" patented technology

Method for preparing anti-inflammatory and anti-tumor active ingredient group from liquorice dregs and application thereof

ActiveCN102552239BClear compositionThe content of main components is clearAntipyreticAnalgesicsChemistryChromatographic separation
The invention provides a method for preparing an anti-inflammatory and anti-tumor active ingredient group from liquorice dregs and an application of the anti-inflammatory and anti-tumor active ingredient group. The anti-inflammatory and anti-tumor active ingredient group prepared from the liquorice dregs comprises 13 flavone compounds; and the method for preparing the anti-inflammatory and anti-tumor active ingredient group from the liquorice dregs comprises the following steps: drying liquorice dregs; crushing the liquorice dregs; by using a solvent extracting method, extracting the liquorice dregs by ethanol or methanol; decompressing and recycling an extraction liquor so as to obtain a crude extract; suspending the crude extract by a distilled water so as to obtain an extract suspension; extracting the extract suspension by petroleum ether or cyclohexane and ethyl acetate in sequence; separating an ethyl acetate extract by silica gel column chromatography; eluting the separated ethyl acetate extract by petroleum ether / ethyl acetate or petroleum ether / acetone mixed solvent in a gradient way; separating an obtained fraction by polyamide column chromatography; and eluting the separated fraction by methanol / water or ethanol / water as mobile phase so as to obtain the active ingredient group. The anti-inflammatory and anti-tumor active ingredient group prepared by using the method provided by the invention, has the advantages of explicit composition, effects of suppressing the growth, proliferation and migration of tumor cell, quinone reductase inducing effect, tumor angiogenesis suppressing effect and anti-inflammatory effect.
Owner:SHENYANG PHARMA UNIVERSITY

A kind of environment-friendly thermosetting acrylic resin and preparation method thereof

ActiveCN108976337BMeet the requirements of the new regulationsCoatingsPolymer scienceFluorescence
The invention relates to a preparation method of an environmental-friendly thermosetting acrylic resin and belongs to the technical field of high polymer materials. The preparation method comprises the following raw materials in parts by weight: acetate solvents at the kettle bottom, a mixture of monomers and initiators, namely methyl methacrylate, tert-butyl methacrylate, styrene, n-butyl acrylate, hydroxy-propyl acrylate, acrylic acid, 1,1-di-tert-butyl peroxide cyclohexane and acetate solvents; supplementary initiators comprising 1,1-di-tert-butyl peroxide cyclohexane and acetate solvents;and diluents comprising the acetate solvents. According to the environmental-friendly thermosetting acrylic resin disclosed by the invention, the content of total benzene series in the resin per 1m<3>is less than 5mg. The powder charge coating prepared by adopting the environmental-friendly thermosetting acrylic resin disclosed by the invention has extremely low benzene content, the temperature resistance reaches 220 DEG C or higher, the value of readily oxidizable substances in the coating is greatly reduced, the total amount on an aluminum foil of 300 square centimeters is less than 1.5ml,fluorescence is not detected in the coating, and any heavy metal does not exist.
Owner:莱阳红安化工有限公司

Method for preparing ethyl oleate from Lauraceae plants

The invention provides a method for preparing ethyl oleate from Lauraceae plants. The method comprises the following steps: washing the Lauraceae plants, airing, drying, and crushing to form powder; carrying out immersing extraction on the powder by using ethanol at normal temperature, filtering, and carrying out reduced pressure vacuum concentration on the obtained filtrate; dissolving the obtained extract liquid concentrate in deionized water, and extracting by using petroleum ether or ethyl acetate; carrying out reduced pressure vacuum concentration on the extracted petroleum ether or ethyl acetate phase, and carrying out gradient elution by adopting a silica gel column with a petroleum ether-ethyl acetate system or a cyclohexane-ethyl acetate system as a mobile phase to increase the proportion of ethyl acetate; carrying out TLC detection to find the target product after the elution, collecting the target product, and carrying out reduced pressure vacuum concentration; and further purifying the finally obtained concentrate by allowing the concentrate to go through the gel column with a chloroform-methanol system as a mobile phase in order to obtain light yellow oil which is ethyl oleate. The method for preparing ethyl oleate has the advantages of simple operation, low cost, and high purity of the obtained product.
Owner:SHANGHAI JIAO TONG UNIV

A method for identifying hibiscus bark in a compound traditional Chinese medicine

The invention discloses a method for identifying cortex pseudolaricis in a traditional Chinese medicinal compound. The method comprises the following steps: (1) adding a sample onto a polyamide column, eluting with a mixed solution, eluting with an organic solvent A, collecting the eluting liquid, drying by distillation, dissolving residues with the organic solvent to serve as a test-sample solution; (2) treating a cortex pseudolaricis control medicinal material with an organic solvent B, drying the filtrate by distillation, dissolving the residues with the organic solvent B to serve as a control medicinal material solution; and (3) taking 2-6mu L of the test sample solution and 2-6mu L of the control medicinal material solution, respectively applying the solutions to the same silica gel chromatographic sheet, taking a mixed solution of cyclohexane-ethyl acetate as a developing solvent, developing, taking out, drying in the air, and inspecting under a 365nm ultraviolet lamp. The identification method can be used for effectively removing impurities in a sample for test, the main ingredient loss is relatively small, and the chromatogram of the test-sample solution has clear and easily-distinguished spots, application of benzene and other reagent with relatively high toxicity can be avoided. The method has the advantages of high specificity, good repeatability, high sensitivity, environment friendliness and the like.
Owner:GUANGZHOU BAIYUNSHAN JINGXIUTANG PHARM CO LTD

A kind of TLC identification method of fried peach kernel and its preparation

The invention provides a thin-layer chromatography identification method for Semen Persicae Preparata and its preparations, which is characterized by including the steps of a, preparing a control medicinal material solution, to be specific, taking Semen Persicae control medicinal material powder, adding sodium hydroxide solution, extracting, centrifuging, collecting supernate, adding chloroform for extracting, collecting lower extract and upper solution, extracting in the same way, combining the extracts, drying by evaporating, and adding methanol for dissolving to obtain the control medicinalmaterial solution; b, preparing a test article solution, to be specific, grinding a test article, and preparing the test article solution in the same way as the control medicinal material solution; c, measuring by thin-layer chromatography, to be specific, dropwise adding the control medicinal material solution and the test article solution to a same silica gel G plate, developing with cyclohexane-ethyl acetate as a developer, extracting, airing, spraying 10% ethanol sulfate solution, heating until spots are clear, and inspecting under an ultraviolet light. The method herein is suitable for quickly and effectively distinguishing Semen Persicae Preparata and its preparations, and Semen Persicae, Semen Persicae Preparata and their preparations. The method herein has good operational convenience, high precision, high sensitivity and good stability and has a good application prospect.
Owner:SICHUAN NEO GREEN PHARMA TECH DEV
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