14 results about "Flavanolol" patented technology

The invention provides a detection method of flavan-3-alcohol sulfonate and application of the detection method. The method comprises the following specific steps: preparing and separating flavane-3-alcohol sulfonate, analyzing and screening molecular characteristic correlation and mass spectrum signal response, identifying the structure of flavane-3-alcohol sulfonate, drawing a standard curve of a flavane-3-alcohol sulfonate standard product, and detecting and analyzing flavane-3-alcohol sulfonate in wine. According to the invention, the epicatechin-(4beta)-sulfonate and the epigallocatechin-(4beta)-sulfonate are obtained by inserting sulfonyl into catechin compounds for preparation and separation, and the epicatechin-(4beta)-sulfonate and the epigallocatechin-(4beta)-sulfonate are used as standard substances for detecting the flavan-3-alcohol sulfonate in the grape wine and are applied to detection and analysis of the flavan-3-alcohol sulfonate in the grape wine. The method provided by the invention has the characteristics of simple and rapid compound synthesis route, easy control of operation conditions, high identification accuracy and sensitivity and strong specificity, provides a good method reference for detection of flavan-3-alcohol sulfonate in the wine aging process, and ensures the fragrant and mellow flavor and taste of wine.

The present invention discloses a method for asymmetric transfer hydrogenation synthesis of chiral flavanol compounds by dynamic kinetic resolution, and the catalyst used is a chiral ruthenium diamine complex. Through this method, asymmetric transfer hydrogenation of flavanone derivatives can be realized, and optically pure flavanol compounds containing three consecutive chiral centers can be obtained in high yield (the enantiomeric excess can reach 99%, and the diastereomeric ratio can reach >20:1). The present invention has high enantioselectivity and diastereoselectivity, is simple and easy to operate, the catalyst is commercially available, the reaction conditions are mild, the energy consumption is low, it is environmentally friendly and has good yield, and gram-scale experiments can be realized without loss of activity and enantioselectivity.

The present disclosure relates to compositions of biocompounds derived from cacao, mainly aromatic compounds such as flavanols and methylxanthines in the form of suspended particles, and to methods for producing the compositions from cacao beans, in particular unfermented cacao beans. The disclosed compositions have high concentrations of epicatechin, procyanidin B2 and theobromine and demonstrate high bioavailability in in vitro tests. These results suggest that the compositions developed are potentially useful for producing functional foods.

The invention relates to the technical field of coreopsis tinctoria refined components and preparation and application, and provides a coreopsis tinctoria refined component and a preparation method and application thereof.The coreopsis tinctoria refined component comprises, by mass, 11 specific components of phenolic acids, flavonol, flavanol and flavonoid, and the 11 specific components comprise, by mass, 2 parts of gallic acid, 1 part of potassium sorbate, 1 part of potassium sorbate, 1 part of potassium sorbate and 1 part of potassium sorbate. The health-care food is prepared from the following raw materials in parts by weight: 3 parts of chlorogenic acid, 14 parts of quercetin, 18 parts of catechin, 5 parts of citric acid, 2-3 parts of procyanidine B, 3 parts of (+)-epicatechin, 1-31 parts of 31 parts of procyanidine C, 14 parts of rutin, 4 parts of camphanol-3-O-rutinoside and 2 parts of isorhamnetin-3-O-rutinoside. The snow chrysanthemum is Changbai Mountain snow chrysanthemum. Animal experiments show that the refined component can significantly reduce the content of total cholesterol and triglyceride in serum of a high-fat model rat, the specific component with blood fat regulating activity is prepared from Changbai Mountain snow chrysanthemum, and a new choice is provided for non-drug intervention of dyslipidemia.

A composition for forming a protective film for a wet etching solution for semiconductors, comprising: component (A): a film-forming component; component (B): a compound selected from the group consisting of a condensed tannin (b1) obtained by polymerizing a compound having a flavanol skeleton, a hydrolyzable tannin (b2) obtained by ester-bonding a sugar and an aromatic compound of gallic acid or ellagic acid, and a flavonoid (b3) derived from a compound having a flavanone skeleton structure; and component (C): a solvent.

The application belongs to the technical field of medicine, and particularly relates to a blood vessel targeting anti-aging oral composition and application thereof. In view of problems such as endothelial dysfunction, matrix sclerosis and accumulation of senescent cells caused by vascular aging, the composition comprises active ingredients: beetroot extract, fisetin, salvianolic acid B, panax notoginseng total saponins, cocoa flavanol, pterostilbene, procyanidin B2, luteolin, nicotinamide riboside and astaxanthin. The composition is prepared by a process of adsorbing astaxanthin on beetroot extract, mixing other active ingredients, fillers and glidants after fisetin and salvianolic acid B are prepared into a solid dispersion, and sequentially cooperating each module, so that the pulse wave transmission velocity can be significantly reduced and the skeletal muscle capillary density can be increased, and the composition is mainly used for preparing a medicine for improving vascular stiffness, promoting microcirculation and removing vascular senescent cells.

The invention discloses a novel compound separated from pogonatum insignis as well as a preparation method and application thereof, and belongs to the technical field of natural medicines. The preparation method comprises the following steps: step 1, taking a pogonatum insignis sun-dried plant, crushing, carrying out heating reflux extraction with 95% ethanol for at least two times (at least 2 hours each time), filtering, combining extracting solutions, and carrying out reduced pressure concentration to obtain a thick extract, so as to obtain a crude extract; 2, dispersing the crude extract with hot water, and sequentially extracting with petroleum ether, dichloromethane, acetic ether and n-butyl alcohol; performing vacuum concentration on the extraction liquid of each polar part to obtain an extract; step 3, loading the dichloromethane extract on an MCI column, and carrying out gradient elution by using a methanol-water solvent system; and 4, concentrating the 50% methanol eluent, preparing a liquid phase, and carrying out isocratic elution by using an acetonitrile-water solvent. According to the invention, the new flavanol compound is separated from pogonatum indarum, and the new compound has good anti-hepatoma activity, and lays a foundation for development and utilization of pogonatum indarum plant resources.

The present invention relates to an eyelid cleansing liquid and wet wipes. The concentrate for eyelid cleansing comprises, by weight, 0.2-2 parts of a terpene compound, 0.1-5 parts of a flavanol derivative, 0.01-5 parts of a flavonoid compound, and 0.1-5 parts of a natural polysaccharide compound. The eyelid cleansing liquid containing the concentrate has the beneficial effect of providing excellent cleaning effects, combining mite removal, anti-inflammatory, anti-irritation, and anti-allergic functions, and can provide users with a convenient, safe, and efficient eyelid cleansing product, thus facilitating its widespread use.

This invention relates to a polyphenolic compound extracted from *Pterocarya stenoptera* and its application in the preparation of drugs for inhibiting enteritis. The polyphenolic compound is the first to be isolated from *Pterocarya stenoptera*, and is a novel, stable, and naturally occurring flavan-3-ol dimer monomer, rather than a polymer degradation product. The preparation method can stably produce high-purity polyphenolic compounds, suitable for the large-scale preparation of novel active ingredients from natural products. Experiments have shown that the polyphenolic compound of this invention possesses intestinal barrier repair capabilities, can inhibit inflammatory factors in the intestinal environment, and is more effective than commonly used clinical drugs. Furthermore, it is naturally derived, highly safe, and has significant clinical application value.

The invention provides a solid biological bacterial fertilizer for rutaceae. The solid biological bacterial fertilizer is prepared by inducing probiotic expression of rutaceae plants, culturing and screening specific flora, and developing a bacterium-charcoal-plant triple interaction carrier based on pomace resource utilization: squeezing and pyrolyzing a pomace-rice hull mixture to prepare a charcoal carrier, and activating flora induction by flavanol; the composite bacterial liquid is wrapped by pectin-activated clay gel to form a soil response type slow release structure, and the solid biological bacterial fertilizer capable of improving rutaceous soil, the yield of agricultural products and the quality of fruits is obtained.

The invention discloses an SbLAC14 gene separated from sorghum as well as an encoding protein and application thereof, and belongs to the field of plant genetic engineering and molecular biology. The laccase gene SbLAC14 with a coding region nucleotide sequence as shown in SEQ ID NO.2 is separated from sorghum for the first time through multi-omics conjoint analysis. Functional verification experiment results show that overexpression of the SbLAC14 gene can improve the content of polymeric proanthocyanidins of wild type arabidopsis thaliana, deepen the color of seed coats, and also can completely recover the polymerization defect of proanthocyanidins of a tt10 mutant and the superficial type of the color of the seed coats, which proves that the SbLAC14 gene has the biological function of catalyzing flavane-3-alcohol monomer polymerization to form proanthocyanidins. The invention provides a gene resource and an operation target with important application value for plant procyanidine synthesis regulation and control, and can be used for tannin metabolic engineering and variety improvement.

The application discloses a new compound separated from haircap moss and a preparation method and application thereof, and belongs to the technical field of natural medicines. The preparation method comprises the following steps: step one, taking the dried haircap moss plants, crushing, extracting with 95% ethanol by heating and refluxing for at least 2 times, each time for at least 2 hours, filtering, combining the extraction liquid, and concentrating into thick extract under reduced pressure to obtain a crude extract; step two, dispersing the crude extract with hot water, and sequentially extracting with petroleum ether, dichloromethane, ethyl acetate and n-butanol; each polar part extraction liquid is concentrated under reduced pressure to obtain an extract; step three, gradient elution of the dichloromethane extract on an MCI column with a methanol-water solvent system; and step four, concentration of the 50% methanol eluent, and then preparation liquid phase, acetonitrile-water solvent isocratic elution. The new flavanol compound is separated from the haircap moss, has good anti-liver cancer activity, and lays a foundation for the development and utilization of the haircap moss plant resources.

The present invention discloses a combined inhibitor for calcite flotation and its application, belonging to the technical field of mineral flotation. The combined inhibitor for calcite flotation includes fluorosulfuric acid, magnesium aluminum silicate, tartaric acid and flavanol compounds. For the first time, the present invention combines fluorosulfuric acid, magnesium aluminum silicate, tartaric acid and flavanol compounds into a combined inhibitor for calcite flotation, which synergistically inhibits calcite, improves the high recovery and high grade effects of fluorite concentrate, and the chemical properties of the combined inhibitor are stable. In addition, the present invention applies the combined inhibitor to the fluorite and calcite flotation process, and the process has good selectivity, high separation efficiency, high recovery rate, low ore dressing cost, simple and reliable process flow, and stable indexes.

To provide improved compositions with beneficial / synergistic combination of polyphenols.SOLUTION: The present invention provides compositions for inhibiting one or more enzymes involved in pathways associated with health and healthy aging, the enzymes being selected from a group consisting of BACE1, CD38, CD73, CDK5, JAK1, JAK2, and JAK3, the composition comprising chemically distinct polyphenols, the polyphenols including organic acids, phenols, flavonols, flavanols, anthocyanins, chlorogenic acids, and betacyanins, the polyphenols being derived from plant material having a red, green, orange-yellow, and purple-blue color, and the polyphenols being in a synergistic combination with respect to inhibition of at least one biochemical marker selected from a group consisting of BACE1, CD38, CD73, CDK5, JAK1, JAK2, and JAK3.SELECTED DRAWING: Figure 32