The invention relates to an oil-powered multi-rotor unmanned aerial vehicle autopilot, which comprises a main processor, a coprocessor, a gyroscope, a barometer, an accelerometer and a compass, wherein the main processor, the coprocessor, the gyroscope, the barometer, the accelerometer and the compass are packaged on a motherboard; the motherboard is externally provided with multi-path control interfaces including a power input interface, a receiver, a steering engine control interface, a data transmission interface and a GPS interface; the gyroscope, the barometer, the accelerometer and the compass are all connected to the main processor; the power input interface is used for connecting an external power supply; and a BEC is used for supplying power and acquiring electric quantity. The oil-powered multi-rotor unmanned aerial vehicle autopilot is an industrial full-function flight control and navigation system specially developed for an oil-powered multi-rotor unmanned aerial vehicle, adopts a self-adaptive flight control and navigation algorithm, has good fault-tolerance performance, integrates a high-precision MEMS inertial sensor and the high-performance central processor, supports full-automatic takeoff and landing and automatic airline operation, is high in anti-electromagnetic interference and anti-vibration capability, and is high in reliability.