The invention relates to quick-fermentation coarse cereal health-care bread. The quick-fermentation coarse cereal health-care bread is characterized by being made through the following steps of performing hydroxypropyl replacement and acetylation replacement on part of hydroxyl on corn starch molecules, so as to obtain acetylated hydroxypropyl starch; then, using wheat flour as a main material, adding corn flour, the acetylated hydroxypropyl starch and other auxiliary materials, performing mixing with a flour mixing agent, performing dough mixing, performing standing, performing rounding, performing shaping, performing leavening, performing shaping once again, performing fermentation once again, finally, performing baking, performing quick cooling, performing packing, and performing mixing so as to obtain the quick-fermentation coarse cereal health-care bread. According to the quick-fermentation coarse cereal health-care bread, the corn being rich in nutrient components is added to flour to be made into the bread, so that the made quick-fermentation coarse cereal health-care bread not only has various health-care functions of resisting ageing, preventing cancer, reducing blood pressure, preventing arteriosclerosis and the like based on common bread, opens up a new way for deep processing of the corn, and has a broad market prospect.