The invention relates to a physical therapeutic
electrode slice which clamps a self-
adhesive drug-loaded membrane and a preparation method thereof. The physical therapeutic
electrode slice which clamps the self-
adhesive drug-loaded membrane consists of an existing conductive
electrode and the self-
adhesive drug-loaded membrane clamped by a stripping layer, wherein, the self-adhesive drug-loaded membrane consists of a
cushioning layer and a drug-release layer. The preparation method of the physical therapeutic electrode slice comprises three processes which are the preparation of gel material for the
cushioning layer, the preparation of gel material for the drug-release layer and the preparation of the physical therapeutic electrode slice which clamps the self-adhesive drug-loaded membrane; besides, the gel material for the
cushioning layer is essentially made from
chitosan and
polyvinyl alcohol, etc. and the gel material for the drug-release layer is essentially made from carbomer and
alginic acid, etc. The physical therapeutic electrode slice can guarantee the stability of the environment of the drug carried by the slice and effectively reduces the competitive transfer of
ion during the electric treatment process and improves the penetrating property through
skin of the drug at the same time so as to improve
curative effect. Besides, the physical therapeutic electrode slice which clamps the self-adhesive drug-loaded membrane has simple preparation method and great amount of drug loading, thereby being especially suitable for
Western medicine and
traditional Chinese medicine which are sensitive to pH value.