34 results about "Double stimulation" patented technology

A method of vibration treatment in at least one nasal cavity of a human subject is provided. The method includes the steps of: inserting a first stimulation member in a first nasal cavity; inserting a second stimulation member in a second nasal cavity; securing the first and second stimulation members such that the stimulation members are in fixed positions within the nasal cavities prior to vibration stimulation; arranging each of the first and second stimulation members to abut against tissue within each of the first and second nasal cavities at a first and second pressure; and imparting vibrations to tissue in at least one of the first and second nasal cavities via at least one of the first and second stimulation members.

The invention discloses an acid / base double stimulation responsive nanometer container and a preparation method thereof. According to the nanometer container, mesoporous nanometer silicon dioxide is adopted as a framework; a host-guest compound is formed based on host pillar[5]arene and a guest molecular chain 1,6-(1-(1-methyl)imida zolehexyl)hexamethylene diamine; a supramolecular valve is formed on the surface of a microsphere through modification; a metal corrosion inhibitor is loaded in the microsphere; under the action of pH stimulation, macrocyclic pillar[5]arene in the nanometer container can move, thereby achieving controllable release of the metal corrosion inhibitor; and after the metal corrosion inhibitor enters a coating, metal corrosion can be effectively inhibited. The nanometer container disclosed by the invention has the advantages that the function of response to various external stimuluses can be achieved; double response to acid / base stimulation can be achieved; and the prospect of application to the fields of drug delivery, intelligent anti-corrosive coating and the like is broad.

The invention provides a methane locking alarm which can effectively detect methane concentration and personnel information in a firing area. The methane locking alarm comprises a microcontroller which has operation and treatment actions and is characterized in that an input port of the microcontroller is connected with a methane sensor and a human body sensor, an output port of the microcontroller is connected with an LED digital display, and a control port of the microcontroller is connected with a recording and playing chip; the recording and playing chip is connected with an audible and visual alarm via an audio power amplifier. The methane closing alarm is provided with the methane sensor and the human body sensor, so that the detonation of a detonating cap under the condition that working personnel do not evacuate or the concentration of methane gas exceeds standard; the recording and playing chip and the audible and visual alarm are also arranged, the double stimulation of audible signals and visual signals are adopted to warn the working personnel in a burst area.

The invention discloses a quick spawning method of Atrina pectinata seed shells. The quick spawning method includes following steps: selecting Atrina pectinata seed shells, performing indoor artificial feeding, and rising temperature step by step to promote maturity breeding to enable sexual glands of the Atrina pectinata seed shells to be mature for waiting for delivery; performing low-temperature drying and exposure on the Atrina pectinata seed shells with mature sexual glands; adding filtered seawater into a container where the Atrina pectinata seed shells are placed, continuously inflating, and performing low-temperature water breeding; transferring the Atrina pectinata seed shells into a spawning pool for ovulation and spermiation. Low-temperature drying and exposure and low-temperature water breeding of a period of time are performed on the seed shells waiting for delivery, and then the seed shells are placed in the spawning pool high in temperature. Due to double stimulation of cooling and heating, spawning rate reaches higher than 60%. By using the quick spawning method, the problem that indoor artificial breeding of Atrina pectinata is difficult in parent shell spawning and low in seed shell spawning rate is solved, needs on a large amount of high-quality eggs for artificial breeding of Atrina pectinata are met, and a foundation is provided for artificial large-scale breeding of Atrina pectinata.

The invention discloses a method for preparing double-stimulation responsive surface through secondary photopolymerization, relating to the field of grafting and modification of various base material surfaces. The method comprises the following steps: I, grafting pH responsive compound onto the surface by adopting a cracking type photoinitiator, wherein the pH responsive compound grafted onto the surface can be used as a hydrogen donor and a co-initiator of the next step reaction; and II, performing photopolymerization reaction on the basis by adopting a hydrogen abstracting type initiator, and grafting the double bond-modified photoresponse compound. The method not only has the advantage that the photopolymerization is efficient, energy-saving, economical, environment-friendly, and the like, but also the compound is difficult to drop after being grafted onto the surface through a covalent bond manner. The prepared intelligent surface has good photoresponsiveness, pH responsiveness, and the swelling property and wettability of the surface polymer can be reversibly controlled. The surface has potential application on the aspects of surface molecule switches, surface controlled release and ion adsorption due to good controllable wettability and mechanical effect.

The invention relates to a preparation method and applications of a mesoporous calcium carbonate medicinal composition modified by hyaluronic acid, for effectively simultaneously realizing targeting, controlled release and ultrasonic therapy and ultrasonic imaging combination, and further realizing diagnosis and treatment integration on cancer. The technical scheme is as follows: the preparation method comprises the following steps: modifying hyaluronic acid on aminated calcium carbonate obtained by reacting mesoporous calcium carbonate and 3-aminopropyl triethoxysilane, and then loading a micromolecular sonosensitizer, thus obtaining the mesoporous calcium carbonate medicinal composition modified by hyaluronic acid. The preparation method has the advantages that a preparation process is simple, a method is stable and reliable, the production cost is low, and the prepared mesoporous calcium carbonate modified by hyaluronic acid and the medicinal composition of mesoporous calcium carbonate simultaneously have the efficacies of tumor targeting, in vitro and in vivo double-stimulation (in acid environment and under high-intensity focused ultrasonic condition) sensitive medicine release, sonodynamic therapy and ultrasonic imaging combined diagnosis and treatment integration, belong to an innovation in tumor treatment medicines, and have enormous economic and social benefits.

The invention discloses an artificial electronic cochlea, a speech processor and a method for processing a speech with double stimulation rates. The speed processor and the method are applied to the artificial electronic cochlea, and the method comprises the following steps of: firstly, performing preprocessing, band-pass filtering, half-wave rectification and low-pass filtering on speech signalsto acquire the envelope amplitude of each channel, and adjusting the current amplitude to a working amplitude range; secondly, selecting a plurality of channels of which the envelope amplitudes are more than or equal to a threshold value to form a first part (high-amplitude) channel, and performing pulse sequence modulation with a first (high) stimulation rate on the first part channel; selectinga plurality of channels of which the envelop amplitudes are smaller than the threshold value to form a second part (low-amplitude) channel, and performing pulse sequence modulation with a second (low) stimulation rate on the second part channel; and adopting electronic pulse sequences of the first and second part channels after modulation to stimulate corresponding stimulating electrodes. The artificial electronic cochlea, the speech processor and the method realize the aim of transmitting information on the envelope amplitudes of all the channels to an artificial electronic cochlea patient, and effectively improve the speech recognition effect of the artificial electronic cochlea.

The invention discloses a preparation method of a double-stimulation expanding gel particle for preventing gas channeling in the process of carbon dioxide oil displacement. The method includes: 1), dissolving an acrylamide monomer into water to form a solution, adding a crosslinking agent, a temperature response monomer methacrylic acid N, an N-dimethylaminoethyl ester monomer and carbon dioxide response monomer (2-(methacrylenyl oxide) ethyl) dimethyl-(3-sulfonic acid propyl) ammonium hydroxide to the solution with even stirring to form a mixed monomer solution polymerization system, and feeding nitrogen to the polymerization system to remove dissolved oxygen in the system; 2), mixing the mixed monomer with an initiator solution for polymerization reaction. The gel particle continuous expands under CO2 and thermal stimulation, secondary expansion of the gel particle under the acidic environment is achieved, and long-time blocking function can be played.

Provided is a double-stimulation ultrasonic elliptical vibration processing device. A giant magnetostrictive material is adopted to serve as a drive element, two sets of giant magnetostrictive transducers are arranged in parallel, large-area one-way water-cooling systems are arranged in the transducers, and flexible hinge connection is adopted at vibration output ends. The device has the advantages of being high in output power, loading capacity and energy conversion efficiency, wide in bandwidth, compact and reasonable in structure and the like, and can be widely applied to various ultrasonic elliptical vibration processing operating conditions.

The invention provides an electrode device for simulating the anal canal and the rectum. The electrode device for simulating the anal canal and the rectum comprises a rubber balloon used for being placed in the rectum of the human body, the surface of the rubber balloon is provided with four electrodes, a rectum pressure sensor is arranged besides each electrode, the rear end of the rubber balloon is provided with a cylindrical sponge body which corresponds to the anal canal position of the human body and is used for fixing and supporting, the cylindrical sponge body is provided with one or more ring-shaped electrodes, a corresponding anal canal pressure sensor is arranged besides each ring-shaped electrode, a supporting guide tube is arranged inside the rubber balloon and the cylindrical sponge body in a penetrating mode, and a ventilating tube for inflating and deflating of the balloon is arranged inside the supporting guide tube. Each electrode is connected with a motor control wirer, each rectum pressure sensor is connected with a signal transmitting wire, a ring-shaped electrode control wire is led out of each ring-shaped electrode, a signal transmitting wire is led out of each anal canal pressure sensor, and all the control wires and the transmitting wires form a wiring harness, and the wiring harness is led out of the supporting guide tube.

The invention relates to a preparation method of a high-strength cellulose-based nanocomposite temperature-pH dual-stimuli-responsive gel. The gel uses POSS cross-linked responsive polymer nanofibers obtained by electrospinning as a fiber reinforcement, which is introduced into the dissolved cellulose solution, and a composite gel is formed by cross-linking the cellulose and freezing. The gel has high strength, significant swelling difference under different temperature and pH environments, fast response rate and good biocompatibility, and can be applied in the fields of sustained drug release and tissue engineering.