The invention discloses a method for measuring the size of a nonbonding area on a bonding device structure. According to the method, light capable of penetrating through the bonding device structure to be measured is adopted to shine on the bonding device structure to be measured so that a Newton ring can be formed at the position corresponding to the nonbonding area in the light incidence direction, then the width, in the direction perpendicular to the light incidence direction, of the Newton ring is measured by means of an optical measuring microscope, and then the width, in the direction perpendicular to the light incidence direction, of the nonbonding area is obtained. According to the method, the measurement of the size of the nonbonding area on the bonding device structure is achieved by means of the Newton ring principle, an accurate measurement result can be obtained, no damage can be caused to the bonding device structure to be measured serving as a sample during measurement, and then production cost is reduced. Furthermore, the method can be applied to bonding device structures formed by bonding of wafers the thickness of each of which is o micron - 775 microns, or chips or other silicon substrates, the method supports substrate doping, the application range is wide, and practicality is high.