The invention discloses a chemical reaction lifesaving nose plug based on a dielectric elastomer, which comprises a spherical inner plug. Limiting magnetic blocks are arranged on the left side of thefilter cotton on the inner surface of the inner cavity of the plug cylinder; an opening and closing mechanism is arranged between the limiting magnetic blocks on the inner surface of the inner cavityof the plug cylinder; a dielectric elastomer power generation mechanism is arranged at the bottom of the inner surface of the inner cavity of the plug cylinder and on the left side of the limiting magnetic block; and the side, away from the spherical inner plug, of the plug cylinder communicates with a chemical reaction mechanism, a circulating mechanism is arranged in the middle of the side, awayfrom the plug cylinder, of an inner cavity of the chemical reaction mechanism, and an anti-disengaging mechanism is arranged at the position, close to the spherical inner plug, of the outer surface of the plug cylinder. According to the chemical reaction lifesaving nose plug based on a dielectric elastomer, which relates to the technical field of nose plugs, the device is small in size, capable of conducting dielectric elastic power generation through breathing and conducting electrolysis oxygen generation on water, suitable for being used in various different environments, capable of conducting oxygen generation for a long time, convenient to carry, effective in supply and capable of guaranteeing life safety in the rescue process.