The invention discloses a method for culturing potatoes in a mountainous district. The method comprises the following steps of: A, variety selection: selecting a variety with excellent stress resistance and yielding ability and detoxified seed potatoes according to the ecology, climate, height above sea level and regional division of labor of the mountainous district; B, seeding and rational close planting: seeding in time so as to ensure that no late frost is met during emergence of seedlings, wherein the early variety is dense within a reasonable density range, the interplanting density is 2,500-3,600 plants per Mu, and the pure planting density is 4,000-4,800 plants per Mu; C, fertilization: (1) combining an organic fertilizer and an inorganic fertilizer, and (2) carrying out nutritional regulation on leaves, spraying a 45-60PPM (Parts Per ,Million) paclobutrazol solution on leaves during a squaring stage, spraying a 0.25%-0.35% monopotassium phosphate solution on leaves during a full-bloom stage, and removing flower buds during the squaring stage, thus improving the potato yield; and D, integrated control of pest and disease damage: carrying out integrated control according to the occurrence condition of pest and disease damage during the growing period. The method disclosed by the invention is easy to practice and simple and convenient to operate, adopts the excellent potato variety and the detoxified seed potatoes, is timely in seeding, rational in close planting and scientific in fertilization, and can be used for improving the yield and quality of the potatoes.