48results about How to "Good binding properties" patented technology

An electrode including a binder comprising a waterborne polyurethane polymer compound and an electrode active material is provided. The waterborne polyurethane polymer compound improves the binding properties of the electrode. In addition, the polymer compound disperses well in water and is hardened through a crosslinking reaction to increase elastic force, thereby enabling adjustment of elastic and binding forces. As a result, a battery including the polymer compound has excellent recovery and charge / discharge properties.

The invention provides two specific T cell receptors targeting G12V or G12C mutation epitopes of a KRAS gene and an anti-tumor application. The two T cell receptors respectively consist of an alpha peptide chain and a beta peptide chain. The invention also provides an antigen binding fragment of the T cell receptors, nucleic acid encoding the antigen binding fragment, a vector containing the nucleic acid, and a host cell containing the vector. The invention further provides a method for preparing a G12V mutation-specific T cell receptor of KRAS or an antigen-binding fragment thereof. The specific T cell receptor and the antigen binding fragment thereof can be used as immune effect activators to stimulate the immune response of the body, thereby generating the action effect of resisting tumors and other diseases.

The invention discloses modified MXenes powder as well as a preparation method and application thereof. The modified MXenes powder is prepared from a MXenes matrix which is of a layer structure and anano metal particle which is distributed between layers and / or on the external surface of the MXenes matrix; the modified MXenes powder is prepared through a metal ion intercalation method; the modified MXenes powder is used as a reinforcing phase to reinforce a metal material; and an obtained metal based composite material not only has excellent mechanical characteristics of high strength, high hardness, high wear resistance and high ductility and the like, but also has favorable electric conductivity and heat conductivity.

A semiconductor device includes a supporting substrate, a conductive layer placed on the supporting substrate, and at least one group III nitride semiconductor layer placed on the conductive layer. Of the group III nitride semiconductor layers, a conductive-layer-neighboring group III nitride semiconductor layer has n type conductivity, dislocation density of at most 1×107 cm−2, and oxygen concentration of at most 5×1018 cm−3. Thus, an n-down type device having a semiconductor layer of high crystallinity can be provided.

An aqueous binder composition for mineral fibres comprises a water-soluble binder component obtainable by reacting, in one or more steps, at least one alkanolamine, at least one carboxylic anhydride and at least one polyalkylene glycol component selected from polyalkylene glycols, copolymers and derivates thereof and, optionally, treating the reaction product with a base.

The invention provides an aluminum alloy and polyphenylene sulfide thermal resin composite material as well as a preparation method thereof. The composite material consists of two parts including an aluminum alloy component and polyphenylene sulfide thermal resin; the surface of the aluminum alloy component is successively subjected to surface pretreatment, alkaline etching processing, film formation treatment and microporous expansion treatment, and then the surface of the aluminum alloy component with expansion micropores is subjected to polyphenylene sulfide thermal resin coating and lamination treatment so as to be combined into an integrated aluminum plastic composite material. According to the invention, the surface of the aluminum alloy component is subjected to phosphoric acid film formation treatment so as to obtain uniform micropores, then the micropores are expanded, and then the surface of the aluminum alloy component and the expanded micropores are subjected to polyphenylene sulfide thermal resin coating and lamination treatment, so that the combination force between the surface of the aluminum alloy component and the expanded micropores increases greatly, and the aluminum plastic composite material with a favorable combination performance is prepared; the polyphenylene sulfide thermal resin, the surface of which is coated and laminated, cannot be stripped off from the aluminum alloy component, and metal shells of electronic equipment and domestic electric appliances can be protected truly and effectively.

The present invention relates to a polypeptide having an amino acid sequence that differs from and is at least 70% identical to the amino acid sequence of hRANK, and which has a binding affinity to RANKL that is at least as high as the binding affinity of hRANK to RANKL, as determined by the functional competition assay described herein.

The invention discloses an anti-corrosion and heat-conducting composite coating on the light-alloy radiator surface, a preparation method of the anti-corrosion and heat-conducting composite coating and a light alloy radiator with the anti-corrosion and heat-conducting composite coating. The composite coating comprises a metal oxide layer formed by oxidizing light alloy radiator base metal in situ and an electrophoretic paint film layer provided with carbon nano-particles dispersedly distributed and located on the metal oxide layer in a covering manner. The preparation method comprises the steps that (1), micro-arc oxidation is conducted, and the metal oxide layer formed by oxidizing the light alloy radiator base metal in situ is formed on the surface of the light alloy radiator base material; and (2), electrophoretic deposition is conducted, and the layer of electrophoretic paint film is deposed on the surface of the metal oxide layer. The composite coating has the beneficial effects of being uniform, dense, excellent in anticorrosion performance, good in thermal conductivity, ultralong in service life and the like. The preparation method is environmentally-friendly, safe, reliable, good in repeatability, capable of achieving automatic large-batch industrial production with low cost and short processes.

It is an object to provide a cathode for a secondary lithium battery in which adhesiveness and flexibility thereof are simultaneously achieved and the thickness thereof is made large, and the secondary lithium ion battery that has a large capacity and is excellent in safety and cycle life using the cathode.The cathode includes a current collector and a cathode mixture layer formed on the surface of the current collector. The cathode mixture layer is formed by stacking two layers one on another, each of which contains a cathode active material, a conductive material and a binder, and the cathode active material contains a lithium-containing composite oxide that forms a polyanion. Of the two layers, the binder that composes a first layer that is in contact with the current collector contains a polymer formed by polymerizing at least one of monomers consisting of a monomer derived from 1-olefin and a monomer derived from a vinyl compound; and the binder that forms a second layer formed on the first layer contains a fluorine resin.

The invention relates to a fruit vinegar beverage containing xylo-oligosaccharide, xylitol and corn peptide, belonging to food beverage. The fruit vinegar beverage comprises the components of purifiedwater (63-83%), xylo-oligosaccharide (crystal, 0.5-2%), ylitol (crystal, 10-20%), corn peptide (dry powder, 1.5-5%) and fermented fruit vinegar with the concentration of 4% (5-10%). The components are mixed at the room temperature, sufficiently dissolved, sterilized by a pasteurism and subsequently encapsulated, thus composing the beverage with different component proportions. The fruit vinegar beverage containing xylo-oligosaccharide, xylitol and corn peptide has the advantages of sobering up, protecting liver, beautifying face, eliminating fatigue, reducing blood pressure, reducing cholesterin, reinforcing immunity, stimulating bowels evacuation and the like, has no additives such as sugar, preservative, essence, pigment and the like, has no side effects with proper drinking, and can bewidely applied to general people and special people who drink wine and have the disease of diabetes.

While a semiconductor device is provided with a plurality of element electrodes 5 formed on a semiconductor element 4 and a plurality of lead terminal electrodes 6 formed on a lead frame, the semiconductor device is equipped with a coupling conductor which electrically connects at least one electrode among the above-described element electrodes 5 to at least one electrode among the above-described lead terminal electrodes 6; the above-described coupling conductor is manufactured by a first conductor 1 and a second conductor 2, the major components of which are metals; the first conductor 1 has been electrically connected to the second conductor 2; and the element electrodes 5 and the lead terminal electrodes 6 have been electrically connected to the second electrode 2 respectively.

The disclosure relates to charge-engineered antibodies and penetration-enhanced targeted proteins and their uses for therapeutic treatment or therapeutics delivery.

A coated layer of ceramics contains cubic-phase ZrW2O8 sosoloid microcrystal doped by 3-valence metal element, Mo, or P and non-crystal glass, phase, and is prepared through preparing wet gel of multi-element tungstate, centrifugal coating on the zero-expansion quartz glass substrate several times, and heat treating. Its advantage is negative expansion coefficient (-2.0- -0.3X10 to the power -6 / deg.C for -20-80 deg.C).

An aqueous binder composition for mineral fibres comprises: a water-soluble binder component obtainable by reacting at least one alkanolamine with at least one carboxylic anhydride in proportions such that the ratio of equivalents of amine groups plus hydroxy groups (NH+OH), excluding urea, to equivalents of carboxy groups (COOH) in the binder component is within the range of from about 0.6 to about 1.5 and, optionally, treating the reaction product with a base; and urea in an amount of from about 1 to about 25 wt %, based on solids of the binder composition; the alkanolamine, carboxylic anhydride and urea reactants being employed in proportions such that the ratio of total equivalents of amine groups plus hydroxy groups (NH+OH), including urea, to equivalents of carboxy groups (COOH) in the binder composition is between and includes the following lower limit x and upper limit y: Formulae (I) and (II).x(min)=(NH+OH)COOH=0.04×wt.%Urea+0.6(I)y(max)=(NH+OH)COOH=0.04×wt.%Urea+1.5(II)

While a semiconductor device is provided with a plurality of element electrodes 5 formed on a semiconductor element 4 and a plurality of lead terminal electrodes 6 formed on a lead frame, the semiconductor device is equipped with a coupling conductor which electrically connects at least one electrode among the above-described element electrodes 5 to at least one electrode among the above-described lead terminal electrodes 6; the above-described coupling conductor is manufactured by a first conductor 1 and a second conductor 2, the major components of which are metals; the first conductor 1 has been electrically connected to the second conductor 2; and the element electrodes 5 and the lead terminal electrodes 6 have been electrically connected to the second conductor 2 respectively.

Disclosed is an aqueous binder composition for mineral fibers that comprises a water-soluble binder component produced by reacting, in one or more steps, at least one alkanolamine, at least one carboxylic anhydride and at least one polyalkylene glycol component selected from polyalkylene glycols, copolymers and derivates thereof and, optionally, treating the reaction product with a base.

The invention relates to a method for improving the high-temperature creep performance of a titanium alloy substrate. According to the method for improving the high-temperature creep performance of the titanium alloy substrate, the high-energy plasma spray-plating technology is used for preparing a nickel-based alloy bottom layer and a ceramic surface layer on the surface of a titanium alloy to obtain a thermal-barrier function layer with high bonding and no influence on the surface structure of the substrate. The process flow is controlled strictly with reasonable spray-plating process parameters, so that the porosity of a coating is controlled within a reasonable range, and the comprehensive mechanical properties are effectively improved. The deposited thermal barrier function layer caneffectively restrain the creep deformation of the titanium alloy substrate while effectively improving the high temperature oxidation resistance and thermal insulation performance of the titanium alloy, and the service life of the titanium alloy part is greatly prolonged.

The invention discloses a nano imprinting device and method for imaging a sapphire substrate. The nano imprinting device comprises a nano imprinting mould, an ultraviolet nano imprinting resist, the sapphire substrate and an exposure ultraviolet light source, wherein the ultraviolet nano imprinting resist is spread on the sapphire substrate, the exposure ultraviolet light source is arranged below the sapphire substrate, and a characteristic cavity is arranged on the nano imprinting mould to form a characteristic image on the mould. By using a modified fluorocarbon resin-based hard polymer mould which has lowest surface energy and the advantages of a soft mould and a hard mould and better mechanical and physical performances and by combining the sapphire substrate which has better light transmission property relative to ultraviolet rays, the above-4 inch large-size wafer level nano imaged sapphire substrate is manufactured in a low-cost, high-productivity and large-scale manner. The invention can also be used for imaging other transparent substrates (such as a ZnO substrate).

The present invention provides a cosmetic powder composition that has superior aesthetic properties over the prior art. The present invention is preferably a pressed powder cosmetic composition that includes silicone elastomer particles that have a JISA hardness index less than about 45. The cosmetic powder cosmetic compositions of the present invention have a hardness value less than about 1500 grams and / or a percent recovery value greater than about 25.

The present invention relates to a polypeptide having an amino acid sequence that differs from and is at least 70% identical to the amino acid sequence of hRANK, and which has a binding affinity to RANKL that is at least as high as the binding affinity of hRANK to RANKL, as determined by the functional competition assay described herein.

There is provided a member for a semiconductor device, such as a substrate, having an excellent resin bonding property capable of improving resin bonding strength at the time the member for a semiconductor device being bonded with resin and maintaining a high resin bonding strength even after various reliability tests, such as a thermal cycling test, are performed. The member for a semiconductor device comprises a base member 1 made of an alloy or composite mainly composed of Cu and W and / or Mo, an alloy or composite mainly composed of Al-SiC, or an alloy or composite mainly composed of Si-SiC. A coating layer made of a hard carbon film 2 is provided on at least a surface of the base member 1 on which at least another member for the semiconductor device, such as a package, is bonded with a resin. It is preferable that the base member 1 have a surface roughness of 0.1 to 20 mu m in Rmax. It is preferable that the hard carbon film 2 have a thickness of 0.1 to 10 mu m.

The invention provides a T cell epitope specific T cell receptor m2P8D TCR of a human papilloma virus E6 gene, a humanized form h2P8D TCR of the T cell epitope specific T cell receptor m2P8D TCR, andantigen binding fragments of the m2P8D TCR and the h2P8D TCR, and provides nucleic acids encoding the m2P8D TCR, vectors containing the vectors, wherein the two T cell receptors are respectively composed of alpha and beta peptide chains, and also provides nucleic acids encoding the two T cell receptors, a vector containing the nucleic acids, a host cell containing the vector, and anti-tumor applications of the two T cell receptors. The invention further provides a T cell epitope specific T cell receptor m2P8D TCR of the human papilloma virus E6 gene, a humanized form h2P8D TCR of the human papilloma virus E6 gene and preparation methods of the T cell epitope specific T cell receptor m2P8D TCR and the humanized form h2P8D TCR. The two specific T cell receptors and the antigen binding fragments thereof can be used as immune effect activators to stimulate the immune response of the body, thereby generating the action effect of resisting tumors and other diseases.

The invention provides a simulation method for strengthening and lightening an airship gasbag of a stratospheric airship, the stratospheric airship and a manufacturing method for the stratospheric airship. The simulation method comprises the following steps of (1), determining a basic shape of the stratospheric airship needed to be researched, and performing modeling on the shape; (2) performing simulation calculation to obtain airship gasbag surface stress distribution of the airship under a maximum overpressure condition; (3) according to related characteristics and a safety coefficient of an airship gasbag material, defining that an airship gasbag surface stress of the airship under the maximum overpressure condition is greater than a maximum safety stress, and serving as a reinforcement rib strengthening region; (4) selecting and using a proper reinforcement rib material to meet a lightweight requirement; arranging a plurality of reinforcement fiber ribs in circumferential and longitudinal directions in a simulated manner in the reinforcement rib strengthening region to strengthen the airship gasbag; and (5) after the airship gasbag is strengthened, performing simulation calculation again to obtain the airship gasbag surface stress distribution, and according to the maximum stress, selecting a proper low-density material to be applied to the airship gasbag.

The invention discloses preparation of a monoclonal antibody of OTUD5 and an application of the OTUD5 in cancer therapy. Through a lot of experiments and data analysis, the results show that OTUD5 is closely associated with occurrence and transfer expression of a breast cancer, the OTUD5 can be applied to treatment of the breast cancer as a therapeutic target. In addition, through improved monoclonal antibody of the OTUD5, the antibody has relatively good binding characteristics.

The invention belongs to the field of optical power detection, and especially relates to an optical power detection device of portable split-ring resonator loaded patch photoresistor. The device comprises a microwave resonance structure, a scalar network analyzer and a single-chip microcomputer module, the microwave resonance structure adopts a split-ring resonator circuit, and the patch photoresistor is loaded at an opening of the split-ring resonator circuit; when illumination irradiated on the patch photoresistor is changed, the resonance peak value of the split-ring resonator circuit is changed, the resonance peak value is detected through the scalar network analyzer, then the resonance peak value offset detection is realized through the single-chip microcomputer module, and thus the optical power detection is realized. According to the optical power detection device, the photosensitive characteristic and the microwave resonance characteristic of a semiconductor material are perfectly combined, and the detection sensitivity of optical (infrared) weak signals is improved by several orders of magnitudes; and meanwhile, the device has the advantages of being small in structure, light in weight, low in cost, free of environmental interference, convenient to carry and the like.

The present application discloses in detail mutant ligands of the human G protein alpha-subunit -Gαi1-, wherein at least one amino acid residue has been replaced with alanine if the at least one amino acid residue is a non-alanine residue, or at least one amino acid residue has been replace with glycine if the at least one amino acid residue is alanine and wherein the at least one amino acid residue is comprised in a first group containing of the amino acid residues with position R32A, K54A, I55A, I56A, H57A, R176A, E245A, Y296A, T327A, N331A, V332A and D350A or is comprised in a second group containing G42A, A59G, T177A, D200A, A226G, E297A, A300G and F334A or is comprised in a third group containing V50A, A59G, R178A 30 and K180A.

The present invention provides human papillomavirus E6 gene T cell epitope-specific T cell receptor murine m2P8D TCR, its humanized form h2P8D TCR, and their antigen-binding fragments. The two T cell receptors are composed of α , β two peptide chains, and also provide nucleic acid encoding them, the vector containing the nucleic acid, the host cell containing the vector and their anti-tumor application; also provide the T cell epitope specific T cell of human papillomavirus E6 gene Cell receptor murine m2P8D TCR, its humanized form h2P8D TCR and methods for their preparation. The two specific T cell receptors and antigen-binding fragments thereof can serve as immune effector activators to stimulate the immune response of the body, thereby producing anti-tumor and other diseases.

The invention provides a simulation method for strengthening and lightening an airship gasbag of a stratospheric airship, the stratospheric airship and a manufacturing method for the stratospheric airship. The simulation method comprises the following steps of (1), determining a basic shape of the stratospheric airship needed to be researched, and performing modeling on the shape; (2) performing simulation calculation to obtain airship gasbag surface stress distribution of the airship under a maximum overpressure condition; (3) according to related characteristics and a safety coefficient of an airship gasbag material, defining that an airship gasbag surface stress of the airship under the maximum overpressure condition is greater than a maximum safety stress, and serving as a reinforcement rib strengthening region; (4) selecting and using a proper reinforcement rib material to meet a lightweight requirement; arranging a plurality of reinforcement fiber ribs in circumferential and longitudinal directions in a simulated manner in the reinforcement rib strengthening region to strengthen the airship gasbag; and (5) after the airship gasbag is strengthened, performing simulation calculation again to obtain the airship gasbag surface stress distribution, and according to the maximum stress, selecting a proper low-density material to be applied to the airship gasbag.