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57results about How to "Good sensitization effect" patented technology
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Silver-poly dopamine-graphene-modified electrochemical sensor and preparation method thereof
InactiveCN102914580AHigh sensitivityImprove conductivityMaterial electrochemical variablesGraphiteElectrochemistry
The invention discloses a silver-poly dopamine-graphene-composite-modified electrochemical sensor which is mainly characterized in that a silver-poly dopamine-graphene composite membrane is coated on the surface of a glassy carbon electrode. A preparation method of the silver-poly dopamine-graphene-composite-modified electrochemical sensor includes: adding silver-poly dopamine-graphene into dimethylformamide for uniform dispersing so that silver-poly dopamine-graphene dispersion liquid is obtained, then coating the dispersion liquid on the surface of the glassy carbon electrode, and evaporating solvent to obtain the needed sensor. A silver-poly dopamine-graphene composite is prepared only by mixing reactants and stirring at the room temperature. The preparation method is simple, mild in reaction conditions and low in cost. The prepared electrochemical sensor has the advantages of high sensitivity, low detection limit and the like, and is capable of achieving rapid sensitivity determination of guanine and adenine, simple to operate, green and environment-friendly.
Owner:XINYANG NORMAL UNIVERSITY
Multiphoton absorption functional material, composite layer having multiphoton absorption function and mixture, and optical recording medium, photoelectric conversion element, optical control element,
InactiveCN101535886AGood sensitization effectImproved multiphoton absorption efficiencyRecord information storagePhotovoltaic energy generationSurface plasmonPhotoelectric conversion
A multiphoton absorption functional material including one of: fine particles of metal, and fine particles partly coated with the metal, the metal generating enhanced surface plasmon field on a metal surface, wherein the fine particles or the fine particles partly coated with the metal are dispersed in a multiphoton absorption material, and wherein the multiphoton absorption functional material is a bulk body.
Owner:RICOH KK
New use of anti-impaludism medicament hydroxyl chloroquine
InactiveCN101428025AMinimize or control damageClear anti-inflammatory activityOrganic active ingredientsAntineoplastic agentsHydroxychloroquineLysosome
The invention relates to the novel usage of an antimalarial medicine, in particular to the novel usage of hydroxychloroquine having sensitivity enhancing effect on various chemical anti-multiple myeloma medicaments. The novel usage is characterized in the application of hydroxychloroquine in treatment of multiple myeloma through chemotherapeutic medicaments. The hydroxychloroquine can obviously enhance the killing activity of chemotherapeutic medicines such as doxorubicine, epidoxorubicin, cis-platinum and mitoxantrone to multiple myeloma cells, and the killing activity thereof is realized by inhibiting the myeloma cell autophagy signals by hydroxychloroquine. Hydroxychloroquine can induce the quantity of the autophagy lysosomes of the multiple myeloma cells to be increased and the expression of the autophagy-associated albumen LC3-II to be increased.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY
Electrochemical sensor for quickly detecting Sudan I in foods and preparation method thereof
InactiveCN101876645AHigh sensitivityIncrease concentrationMaterial electrochemical variablesElectrical conductorAdhesive
The invention discloses an electrochemical sensor for quickly detecting Sudan I in foods and a preparation method thereof. The preparation method of the sensor comprises the following steps of: uniformly mixing montmorillonite, conductive carbon powder and adhesive at a certain percentage to form a sensitive material; filling the sensitive material in a cavity on the front end of an insulating column and enabling the sensitive material contact with the end of a metal conductor inserted and fixed at the centre of the insulating column. The electrochemical sensor of the invention has the advantages of high sensitivity, low detection limitation, capability of realizing quick detection to the Sudan I in foods, simple and convenient operation, environment-friendliness, wide raw material sources and low cost; moreover, the preparation method is simple.
Owner:HUBEI INSPECTION & QUARANTINE TECH CENT
Synthesis method of high molecular weight polysiloxane containing nitrile group and vinyl at the same time and preparation method of addition type heat vulcanized nitrile silicone rubber
The invention relates to a synthesis method of high molecular weight polysiloxane containing nitrile group and vinyl at the same time and a preparation method of addition type heat vulcanized nitrile silicone rubber. The high molecular weight polysiloxane containing nitrile group and vinyl at the same time is prepared by performing amino group and double bond addition reaction on polysiloxane containing amino group and vinyl at the same time and compound containing unsaturated bonds and nitrile group. The addition type heat vulcanized nitrile silicone rubber is prepared through the synthesized high molecular weight polysiloxane containing nitrile group and vinyl at the same time. The synthesis method is simple and controllable, and high in synthesis efficiency; as the synthesized polysiloxane containing nitrile group and vinyl at the same time contains nitrile groups, the polarity and solubility parameters of polysiloxane are changed, and the prepared addition type heat vulcanized nitrile silicone rubber can have the performance of solvent oil resistance, and can be applied to various oil resistance and low temperature resistance places.
Owner:SHANDONG UNIV
Synthesis of siloxane containing nitrile group and vinyl group at same time and preparation method of room-temperature addition type nitrile silicone rubber
ActiveCN105778105AGood storage stabilityReduces prone to yellowingGroup 4/14 element organic compoundsSynthesis methodsRoom temperature
The invention relates to synthesis of siloxane containing nitrile group and vinyl group at same time and a preparation method of room-temperature addition type nitrile silicone rubber. The siloxane containing the nitrile group and the vinyl group is prepared from the siloxane containing amino group and the vinyl group at the same time, and a vinyl-group-containing compound with unsaturated bonds through an addition reaction of the amino group and the double bonds; the synthesized siloxane containing the nitrile group and the vinyl group at same time is used for preparing the room-temperature addition type nitrile silicone rubber. The synthesis method is simple and controllable, and high in synthesis efficiency. The synthesized siloxane containing the nitrile group and the vinyl group at same time contains the vinyl group so that the polarity and the dissolvability parameters of the siloxane are improved; the room-temperature addition type nitrile silicone rubber prepared from the siloxane containing the nitrile group has a property of resisting solvent oil and can be widely applied to various oil-resisting and low-temperature-resisting fields.
Owner:SHANDONG UNIV
Polymerizable monomer, polymer compound, photocurable resin composition, sealing element for liquid crystal display element, vertical conduction material, and liquid crystal display element
ActiveCN105683225AReduce pollutionHigh sensitivityGroup 4/14 element organic compoundsOther chemical processesEpoxyLiquid-crystal display
A purpose of the present invention is to provide a polymerizable monomer having low contamination with respect to liquid crystals, high sensitivity to light of long wavelengths, and an exceptional sensitizing effect, and a polymer compound obtained by polymerizing the polymerizable monomer. Another purpose of the present invention is to provide a photocurable resin composition containing the polymerizable monomer and / or the polymer compound; a sealing agent for liquid crystal display elements which uses the photocurable resin composition; and a vertical conduction material and liquid crystal display element which are manufactured using the sealing agent for liquid crystal display elements. The present invention is a polymerizable monomer obtained by causing a thioxanthone derivative that has a functional group capable of reacting with a dialkylaminobenzoic acid compound or epoxy group to react with an epoxy group having an unsaturated double bond or an epoxy group having an alkoxysilyl group.
Owner:SEKISUI CHEM CO LTD
LED illuminating device and preparation method thereof
ActiveCN106764483ANot suitable for chippingIncrease productivityElectric circuit arrangementsLuminescent compositionsEngineeringLED circuit
The invention relates to an LED illuminating device and a preparation method thereof. The device is characterized by comprising an LED apparatus, an LED circuit board, a heat dissipator and a power supply controller. The LED apparatus is arranged on the LED circuit board, the LED circuit board is arranged above the heat dissipator, and the power supply controller is connected to the LED circuit board through a wire. The LED illuminating device can emit approximate natural light.
Owner:SHENZHEN YMH INTELLIGENT TECH CO LTD +1
Electrochemical sensor for rapidly measuring carmine and citrine and preparing method thereof
InactiveCN104316583AIncrease concentrationEnhanced electrochemical oxidation signalMaterial electrochemical variablesCarbon paste electrodeGraphite
The invention discloses an electrochemical sensor for rapidly measuring carmine and citrine. The electrochemical sensor at least comprises a carbon paste electrode, wherein the carbon paste electrode comprises a casing and a copper bar, and a cavity is formed in the front end of the casing and filled with carbon paste. The invention further provides a preparing method of the sensor. The preparing method comprises the following steps: S1, dissolving Al(NO3)3.9H2O in secondary water, then adding urea, transferring an obtained solution into a hydrothermal reactor, putting in an oven to react, washing and suction-filtering solids obtained by reaction with the secondary water, drying in the oven, then putting in a muffle furnace and forging to obtain an aluminum oxide material; S2, uniformly mixing the aluminum oxide material, graphite powder and paroline oil to obtain the carbon paste, then pressing the carbon paste into a cavity at the front end of the casing, and abrading and polishing on weighing paper to make the electrochemical sensor for rapidly measuring carmine and citrine. The made electrochemical sensor is simple and convenient to operate, has great environment-friendliness and high flexibility, does not require long-time enrichment and meets the requirements of rapid detection.
Owner:广东省潮州市质量计量监督检测所
Synthesis of high molecular weight nitrile-group-containing polysiloxane and preparation method of peroxide type hot vulcanization nitrile silicone rubber
ActiveCN105601845AHigh synthesis efficiencySynthesis conditions are simplePolymer scienceVulcanization
The invention relates to synthesis of high molecular weight nitrile-group-containing polysiloxane and a preparation method of peroxide type hot vulcanization nitrile silicone rubber. The high molecular weight nitrile-group-containing polysiloxane is prepared by carrying out addition reaction between an amino group and a double bond on polysiloxane containing the amino group and a compound containing an unsaturated bond and a nitrile group. The synthesized high molecular weight nitrile-group-containing polysiloxane (also contains vinyl) is adopted for being compounded with a crosslinking agent, a catalyst used for crosslinking, filler and other auxiliaries, so that the peroxide type hot vulcanization nitrile silicone rubber is prepared. The synthesis of the high molecular weight nitrile-group-containing polysiloxane is simple in synthesis method and controllable, and synthesis efficiency is high; and the peroxide type hot vulcanization nitrile silicone rubber prepared by adopting siloxane containing a nitrile group can have solvent resistance and oil resistance and can be widely applied to various oil resistant and low temperature resistant places.
Owner:SHANDONG UNIV
Sensitivity-enhanced type fiber bragg grating strain sensor based on micrometric displacement amplifying mechanism
ActiveCN109458946ASensitization effect is more obviousSignificant sensitization effectUsing optical meansPhysicsStrain sensor
The invention discloses a sensitivity-enhanced type fiber bragg grating strain sensor based on a micrometric displacement amplifying mechanism, and belongs to a fiber bragg grating sensor technology.The problems that an ordinary fiber bragg grating strain sensor is not high in sensitivity and the micro-strain of the structure cannot be accurately measured are solved. The sensitivity-enhanced typefiber bragg grating strain sensor comprises an upper layer protection shell, a sensitivity-enhanced amplifying mechanism, a bottom layer protection shell and a fiber bragg grating. Two connecting bosses of the sensitivity-enhanced amplifying mechanism can be connected with a measured object through rectangular holes in the bottom layer protection shell. The sensitivity-enhanced amplifying mechanism is further provided with a first-stage level and a second-stage level. The micrometric displacement generated by the measured object is subjected to two-stage amplifying and transmitted to the fiber bragg grating in a bragg grating installation groove. The sensor is remarkable in sensitivity enhancing effect, wide in use range and suitable for measuring the micro-strain of the structure.
Owner:XI AN JIAOTONG UNIV +1
Protein sensitizer of tumor chemotherapeutics
ActiveCN102366627ARapid growth inhibitionFast activityOrganic active ingredientsPeptide/protein ingredientsMutated proteinDaunorubicin
The invention discloses a protein sensitizer of tumor chemotherapeutics and an application thereof, the protein sensitizer comprises Survivin mutant protein, the protein sensitizer has 90% of homology with Survivin through gene engineering preparation, the Survivin comprises one point mutation, multipoint mutation, combinatorial mutation and simultaneous mutation of sites of 20 site, 34 site, 84 site and 117 site. The protein sensitizer is combined with tumor chemotherapeutics for usage, the tumor chemotherapeutics refers to one or more of doxorubicin, epirubicin, daunorubicin or paclitaxel. According to the effect of Survivin protein in cell signal pathway and the influence of Survivin protein on multi-drug resistance reversing, the chemotherapeutics is combined with TmSm, the TmSm is capable of effectively promoting the killing effect of the chemical medicines, effectively reducing the application amount of the chemical medicines and increasing the killing effect of the chemical medicines on cells, and is the effective protein sensitizer of tumor chemotherapeutics.
Owner:EAST CHINA UNIV OF SCI & TECH
Process for preparing rare earth luminescent materials
InactiveUS20030057400A1Good sensitization effectRare earth metal compoundsLuminescent compositionsEuropiumLuminescent material
The present invention relates to a process for preparing rare earth trichromatic phosphor, comprising the following steps: (1) providing a matrix material doping with both europium (Eu) and terbium (Tb); (2) grinding and mixing the said matrix material; and (3) making the product obtained in step (2) to react at 800-1000° C for 3-5 hours. According to the present process, only one matrix material and two rare earth reactive ions (Eu3+, Tb3+) are desired to synthesize rare earth trichromatic phosphor. That is to say, no reducing reagent is needed and thus no pollution is brought.
Owner:CHANGCHUN INST OF APPLIED CHEMISTRY - CHINESE ACAD OF SCI
Preparation method of room-temperature condensation type nitrile silicone rubber
ActiveCN108707232AGood storage stabilityReduces prone to yellowingGroup 4/14 element organic compoundsSolubilityPolymer science
The invention relates to a preparation method of room-temperature condensation type nitrile silicone rubber. The room-temperature condensation type nitrile silicone rubber is prepared by utilizing synthesized cyano-containing siloxane; the cyano-containing siloxane is prepared from the cyano-containing siloxane and a cyano-containing compound containing an unsaturated bond through addition reaction of amino and double bonds. The synthesis method provided by the invention is simple and controllable and is high in synthesis efficiency; the synthesized cyano-containing siloxane contains a cyano group so that the polarity and solubility parameters of the siloxane are changed. The room-temperature condensation type nitrile silicone rubber prepared by utilizing the synthesized cyano-containing siloxane can have the performance of resisting solvent soil and can be widely applied to various oil-resisting and low-temperature-resisting fields.
Owner:SHANDONG UNIV
Bi-Nd-Yb co-doped YAG high-efficiency and wide-spectrum quantum cutting luminescent material
ActiveCN108192613AEfficient broad-spectrum conversion and utilizationHigh energyLuminescent compositionsHigh energyBroadband absorption
The invention provides a Bi-Nd-Yb co-doped YAG high-efficiency and wide-spectrum quantum cutting luminescent material. A composition general formula of the luminescent material is Y3Al5O12:xBi<3+>, yNd<3+>, zYb<3+>, wherein x is greater than or equal to 0.5*10<-2> and less than or equal to 1*10<-2>, y is greater than or equal to 0.5*10<-2> and less than or equal to 2*10<-2> and z is greater than or equal to 1*10<-2> and less than or equal to 10*10<-2>. According to the Bi-Nd-Yb co-doped YAG high-efficiency and wide-spectrum quantum cutting luminescent material provided by the invention, Nd<3+>-Yb<3+> co-doping belongs to two-step energy transmission and has relatively high energy conversion efficiency; Bi<3+> in the luminescent material can be used for effectively expanding an absorption section of Nd<3+> through a sensitization effect; sunlight is subjected to broadband absorption so that high-efficiency and wide-spectrum conversion type near-infrared quantum cutting is realized; finally, the sunlight is sufficiently utilized and the conversion efficiency of a crystalline silicon solar cell is improved.
Owner:HENAN UNIV OF SCI & TECH
Dual-sensitization high-sensitivity FBG temperature sensor and manufacturing method thereof
ActiveCN113125041AImprove response speedGood sensitization effectThermometers using physical/chemical changesEpoxyThermal dilatation
The invention provides a double-sensitization high-sensitivity FBG temperature sensor and a manufacturing method thereof, and the sensor comprises three cylindrical metal tubes, one of the cylindrical metal tubes is a metal housing, the inner diameter of the cylindrical metal tube is slightly larger than the outer diameters of the other two metal tubes, and the middle part of the cylindrical metal tube is provided with a plurality of through holes. Two small metal tubes are connected through epoxy resin glue and embedded into a large metal shell by a certain depth, so that a section of cavity exists in the metal shell, four through holes are formed in the cavity of the metal shell, and the fiber bragg grating is installed in the three metal tubes which are connected in series through glue in a bonding mode. The grating is coated with colloid with a high thermal expansion coefficient; and the high thermal expansion characteristic of the organic polymer on the outer side of the FBG and the influence of thermal expansion and contraction of the metal on the central wavelength are utilized to realize dual temperature sensitization of the FBG, and the response speed and the sensitization effect of the FBG temperature sensor are improved.
Owner:WUHAN UNIV OF TECH
Synthesis of nitrile-containing siloxane and preparation method of room temperature condensation type nitrile silicone rubber
ActiveCN105646565AGood storage stabilityReduces prone to yellowingGroup 4/14 element organic compoundsSolubilityAminosilochrome
The invention relates to synthesis of nitrile-containing siloxane and a preparation method of room temperature condensation type nitrile silicone rubber. The nitrile-containing siloxane is obtained by amino-containing siloxane and a nitrile-containing compound containing an unsaturated bond through an addition reaction of amino and double bond, and further the synthetized nitrile-containing siloxane is used to prepare the room temperature condensation type nitrile silicone rubber. A synthesis method is simple and controllable, the synthesis efficiency is high, and the synthetized nitrile-containing siloxane contains nitrile groups and thus changes the polarity and a solubility parameter of siloxane; the room temperature condensation type nitrile silicone rubber prepared by using the nitrile-containing siloxane has the property of resisting solvent oil, and can be widely applied to various oil-resisting and low temperature-resisting places.
Owner:SHANDONG UNIV
Anticancer composition and application of anticancer composition to preparation of drugs
InactiveCN109432084ASignificant sensitization effectReduce liver toxicityHeavy metal active ingredientsOrganic active ingredientsChemotherapeutic drugsOvarian cancer
The invention discloses an anticancer composition and application of the anticancer composition to preparation of drugs. The anticancer composition comprises silybin and chemotherapeutic drugs. Test results show that the combined application of silybin and chemotherapeutic drugs to preparation of drugs for resisting human ovarian cancer drug-resistant cells is capable of effectively improving thesensibility of the human ovarian cancer drug-resistant cells to the chemotherapeutic drugs and reducing hepatotoxicity induced by the chemotherapeutic drugs.
Owner:WENZHOU MEDICAL UNIV
High-sensitivity fiber grating electric field sensor
InactiveCN109633234ASensitization effect is obviousGood sensitization effectVoltage/current isolationFiberElectric field sensor
The invention discloses a high-sensitivity fiber grating electric field sensor. The high-sensitivity fiber grating electric field sensor comprises an upper metal hemisphere and a lower metal hemisphere; a sensitization amplification mechanism, an optical fiber and an insulating plate are arranged between the upper and lower metal hemispheres; through the two metal hemispheres, electric field signals are sensed; and the design of the sensitization amplification mechanism uses an inverse piezoelectric effect and amplification type sensitization combined method, so that the sensitization effect is more obvious. Voltage signals are transferred to the sensitization amplification mechanism through a lead, so that the sensitization amplification mechanism deforms mechanically; through amplification of the sensitization amplification mechanism, a relatively large deformation amount is output and acts on the optical fiber, so that the central wavelength of the optical fiber changes; and throughdetecting wavelength drift distance, to-be-detected electric field intensity is obtained. The fiber grating sensor is remarkably in sensitization effect, small in volume, wide in application range and suitable for micro strain measurement of structures.
Owner:XI AN JIAOTONG UNIV +1
Erbium silicate with sensitization effect as well as preparation method and application of erbium silicate
ActiveCN104787773AGood sensitization effectShine wellSilicon compoundsLuminescent compositionsSolventPorous silicon
The invention discloses a preparation method of erbium silicate with the sensitization effect. The preparation method comprises steps as follows: porous silicon is rotationally coated with a solution obtained by dissolving an erbium soluble compound in a solvent until the rotational coating quantity reaches (4.44*10<-3>)-(8.89*10<-2>)ml / cm <2>, and after drying, erbium silicate with the sensitization effect is obtained through two steps of heat treatment sequentially. The prepared erbium silicate adopts a core-shell structure comprising a nano-silicon pillar and single-layer erbium silicate covering the surface of the nano-silicon pillar, has the better sensitization effect, can illuminate better under the off-resonance exciting light, and can be applied to the fields of silica-based photoelectricity integration, photo-communication and the like.
Owner:ZHEJIANG UNIV
Lifting system gear shaft torque monitoring device and gear shaft
ActiveCN112763124AImprove anti-electromagnetic interference performanceImprove corrosion resistanceMeasurement of torque/twisting force while tighteningWork measurementData connectionGrating
The invention discloses a lifting system gear shaft torque monitoring device and a gear shaft. The device comprises torque transmission tubes, strain measurement tubes, measurement fiber bragg gratings, transmission optical fibers, a rotary connector, a demodulator and a terminal, the strain measurement tubes are connected between the two adjacent torque transmission tubes, the measurement fiber bragg gratings are attached to the outer walls of the strain measurement tubes, a connecting hole is formed in each strain measurement tube, one ends of the transmission optical fibers penetrate through the connecting holes to be connected with the measuring fiber bragg gratings, the other ends of the transmission optical fibers penetrate through the torque transmission tubes to be connected with the rotary connector, the rotary connector is in data connection with the demodulator, and the demodulator is in data connection with the terminal; and the outer diameter of the torque transmission tubes is more than the outer diameter of the strain measurement tubes. According to the scheme, the torque of the climbing gear shaft can be accurately detected in real time, so that whether loads borne by all transmission devices are balanced or not can be effectively reflected, overload caused by deformation or other reasons of individual lifting systems can be found in time, and accidents are avoided.
Owner:KEEN OFFSHORE ENG CO LTD
A device and method for rapidly detecting total volatile organic compounds
ActiveCN107764806BHigh sensitivityReduce oxidationChemiluminescene/bioluminescencePtru catalystPhotodetector
The invention relates to a device for rapid detection of total volatile organic compounds. The device comprises a plasma generator, an ozone generator and a catalytic luminescence sensing device, wherein the plasma generator is provided with a sample gas inlet and a sample gas outlet. The ozone generator is provided with an ozone outlet. The catalytic luminescence sensing device includes a chemiluminescent reaction chamber with a catalyst inside and a photodetector. The sample gas inlet and the ozone outlet are respectively communicated with the chemiluminescent reaction chamber, respectively.The photodetector detects a catalytic luminescence signal emitted from the chemiluminescent reaction chamber. The invention also relates to a method for rapid detection of the total volatile organiccompounds. The device for rapid detection of the total volatile organic compounds can meet the requirements of rapid, sensitive and simple detection of the TVOC (total volatile organic compounds).
Owner:SUN YAT SEN UNIV
Technology for plating surface of glass fiber with metal layer
InactiveCN110872705AGood sensitization effectLiquid/solution decomposition chemical coatingGlass fiberPhysical chemistry
The invention relates to the technical field of glass fiber production and discloses a technology for plating the surface of glass fiber with a metal layer. The technology needs a device for plating the surface of the glass fiber with the metal layer. The technology comprises the following steps of (1) conducting purifying, wherein heat treatment at the temperature of 205-255 DEG C is conducted onthe glass fiber; (2) conducting coarsening, wherein the glass fiber obtained after oil removal in the step (1) is placed in a coarsening solution, the temperature of the coarsening solution is raisedto 30-40 DEG C, and dipping is conducted for 4-7 min under the condition of keeping the temperature; (3) conducting cleaning, wherein the coarsened glass fiber is flushed with water, so that remaining coarsening liquid on the surface of the glass fiber is removed; (4) conducting sensitizing, wherein the glass fiber washed in the step (3) is placed in a sensitizing solution for sensitizing treatment at the room temperature; (5) conducting activation, wherein the sensitized glass fiber in the step (4) is directly placed in an activation solution, stirring is performed for 3-5 h, and then standing is performed for 1-2 h; (6) conducting cleaning; and (7) conducting drying. The technology for plating the surface of the glass fiber with the metal layer improves layer plating efficiency and safety.
Owner:GUANGZHOU ZHUOYUE POWER NEW ENERGY CO LTD
Adrenal cortical hormone compound preparation
ActiveCN102327274ASmall toxicityLower doseOrganic active ingredientsAntipyreticTolerabilitySide effect
The invention provides an adrenal cortical hormone compound preparation. An active pharmaceutical ingredient in the preparation comprises the following components: adrenal cortical hormone and tetraodotoxin. The purpose of the preparation is identical with that of a hormone drug in the preparation; and the tetraodotoxin can play a sensitizing role in the preparation so as to improve the hormone use effect, reduce the hormone use dose, reduce or eliminate the hormone tolerability, the hormone dependence and the side effect.
Owner:泰州市康特生物工程有限公司
Rhizoma anemarrhenae effective part as well as preparation method and application thereof
InactiveCN105663626AQuality is easy to controlHigh drug safetyMetabolism disorderEndocrine system disorderAdditive ingredientSecondary hyperlipidemia
The invention relates to the technical field of traditional Chinese medicines and in particular discloses a rhizoma anemarrhenae effective part as well as a preparation method and application thereof. The rhizoma anemarrhenae effective part mainly contains rhizoma anemarrhenae total saponins, and main ingredients of the rhizoma anemarrhenae total saponins are rhizoma anemarrhenae saponin BII, rhizoma anemarrhenae saponin BIII and a rhizoma anemarrhenae saponin BIII isomer. Experimental results show that the rhizoma anemarrhenae effective part can obviously improve the sugar tolerance of a diabetic rat at different time points, enhance the insulin sensitivity of a type-II diabetic rat and improve the hyperlipidemia state of the type-II diabetic rat.
Owner:GUANGDONG PHARMA UNIV
A kind of lifting system gear shaft torque monitoring device and gear shaft
ActiveCN112763124BImprove anti-electromagnetic interference performanceImprove corrosion resistanceMeasurement of torque/twisting force while tighteningWork measurementData connectionTorque transmission
Owner:KEEN OFFSHORE ENG CO LTD
Nuclear pore membrane ultraviolet light sensitization device and method
ActiveCN105311969BWavelength concentrationLow calorific valueSemi-permeable membranesWater bathsSource plane
The invention relates to a nuclear pore membrane batch sensitization device. This device is mainly used for batch sensitization treatment of nuclear pore membranes, and its main application fields include nuclear pore membrane product processing, nuclear pore membrane preparation, etc. A nuclear pore membrane ultraviolet light sensitization device, its main feature is to include an unwinder, an ultraviolet sensitizer and a winder; The sensitizing roller and the winding roller on the winding machine pass through the unwinding machine, the ultraviolet sensitizing machine and the winding machine in sequence; The bracket is equipped with an ultraviolet LED surface light source and heat-insulating glass, and a cooling water tank is provided under the heat-insulating glass. connect. The device has the advantages of low working temperature, short sensitization time, high production efficiency, long service life, etc., and can carry out ultraviolet light sensitization treatment of nuclear pore membranes in batches.
Owner:INST OF MODERN PHYSICS CHINESE ACADEMY OF SCI
Synthesis of siloxane containing nitrile group and vinyl group and preparation method of room temperature addition type nitrile silicone rubber
ActiveCN105778105BGood storage stabilityReduces prone to yellowingGroup 4/14 element organic compoundsSynthesis methodsRoom temperature
The invention relates to synthesis of siloxane containing nitrile group and vinyl group at same time and a preparation method of room-temperature addition type nitrile silicone rubber. The siloxane containing the nitrile group and the vinyl group is prepared from the siloxane containing amino group and the vinyl group at the same time, and a vinyl-group-containing compound with unsaturated bonds through an addition reaction of the amino group and the double bonds; the synthesized siloxane containing the nitrile group and the vinyl group at same time is used for preparing the room-temperature addition type nitrile silicone rubber. The synthesis method is simple and controllable, and high in synthesis efficiency. The synthesized siloxane containing the nitrile group and the vinyl group at same time contains the vinyl group so that the polarity and the dissolvability parameters of the siloxane are improved; the room-temperature addition type nitrile silicone rubber prepared from the siloxane containing the nitrile group has a property of resisting solvent oil and can be widely applied to various oil-resisting and low-temperature-resisting fields.
Owner:SHANDONG UNIV
Adrenal cortical hormone compound preparation
ActiveCN102327274BSmall toxicityLower doseOrganic active ingredientsAntipyreticSide effectTolerability
The invention provides an adrenal cortical hormone compound preparation. An active pharmaceutical ingredient in the preparation comprises the following components: adrenal cortical hormone and tetraodotoxin. The purpose of the preparation is identical with that of a hormone drug in the preparation; and the tetraodotoxin can play a sensitizing role in the preparation so as to improve the hormone use effect, reduce the hormone use dose, reduce or eliminate the hormone tolerability, the hormone dependence and the side effect.
Owner:泰州市康特生物工程有限公司
Protein sensitizer of tumor chemotherapeutics
ActiveCN102366627BGrowth does not affectIncrease lethalityOrganic active ingredientsPeptide/protein ingredientsMutated proteinDaunorubicin
The invention discloses a protein sensitizer of tumor chemotherapeutics and an application thereof, the protein sensitizer comprises Survivin mutant protein, the protein sensitizer has 90% of homology with Survivin through gene engineering preparation, the Survivin comprises one point mutation, multipoint mutation, combinatorial mutation and simultaneous mutation of sites of 20 site, 34 site, 84 site and 117 site. The protein sensitizer is combined with tumor chemotherapeutics for usage, the tumor chemotherapeutics refers to one or more of doxorubicin, epirubicin, daunorubicin or paclitaxel. According to the effect of Survivin protein in cell signal pathway and the influence of Survivin protein on multi-drug resistance reversing, the chemotherapeutics is combined with TmSm, the TmSm is capable of effectively promoting the killing effect of the chemical medicines, effectively reducing the application amount of the chemical medicines and increasing the killing effect of the chemical medicines on cells, and is the effective protein sensitizer of tumor chemotherapeutics.
Owner:EAST CHINA UNIV OF SCI & TECH
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