The invention relates to a preparation method and application of a spider thread
drug-loaded oral sustained-release membrane, in particular to a pre-membrane-forming
drug-loading method by blending a
drug solution or a drug composition with a natural spider thread solution, the loaded drug is
inosine, a Kangfuxin drug or a drug composition of the
inosine and the Kangfuxin drug, and the spider thread is Jingzhaochbrachys jingzhaochys jingzhaochys jingzhaochys jingzhaochys jingzhaochys jingzhaochys jingzhaochys. The spider thread drug-loaded oral sustained-release membrane prepared by the method is good in
biocompatibility, can successfully load Kangfuxin drug and / or
inosine drug molecules and slowly release the drug, the
drug release time of the spider thread drug-loaded oral sustained-release membrane in artificial
saliva and the
oral cavity of a
human body is not less than 4 hours, and the spider thread drug-loaded oral sustained-release membrane is not degraded in the artificial
saliva for 160 hours and is degraded in artificial gastric juice for 24 hours; the spider-thread
medicine-carrying oral sustained-release membrane has certain tensile strength and
adhesive force, can be applied to oral buccal membrane parts, gingiva and sublingual parts, is convenient to carry, use and replace in daily life, does not influence the safety of
oral mucosa, and is suitable for
home nursing and inter-
diagnosis treatment of various
oral ulcers.