The invention discloses a hybrid new energy power system set combination optimization method. The method comprises the following steps: step 1, establishing a new energy power system set combination scheduling mathematic model, wherein this step includes establishment of a new energy set optimization scheduling target function, by taking set switch states and power of each set as an input quantity and set operation cost as an output quantity, the target function is shown in the descriptions, minF is a target function when the system operation cost is the smallest, T is a period number of scheduling periods, N is a set number, I<i,t> is an operation state of a set i at t time, when the set is booted, I<i,t>=1, when the set is shut down, I<i,t>=0, P<i,t> is generating power of a thermal power set i at t time, f(P<i,t>) is a generating cost of the thermal power set i at the t time, and S is a starting cost of the thermal power set i; and arrangement of constraint conditions; and step 2, carrying out optimization searching calculation on the mathematic model in the first step by use of a heuristic optimization algorithm. The method provided by the invention has the following advantages: the algorithm is simple in structure, the optimization searching capability of the target function is high, the iteration convergence speed is fast, and the algorithm has quite good stability.