66results about How to "Prevent calcification" patented technology

Modified FGF-23 polypeptides and uses thereof are provided.

The invention discloses an organic compound fertilizer with citrus pomace and a preparation method of the organic compound fertilizer and belongs to the technical field of preparation of organic fertilizers. The preparation method comprises the following steps of reducing the acidity of the citrus pomace by adopting microbial fermentation for deacidification, decomposing nondegradable components such as pectin and cellulose in the citrus pomace by adopting a compound-enzyme preparation, carrying out composting fermentation by microbial liquid inoculant, finally adding batched materials such as urea, monoammonium phosphate and potassium sulfate, and carrying out insect killing, sterilization, granulation, drying, cooling, sieving, coating and packaging to prepare the organic compound fertilizer with rich organic matter and the contents of N, P and K meeting the need of the optimal proportion for growth of citrus. The organic compound fertilizer and the preparation method disclosed by the invention have the advantages that deacidifying yeast is adopted to reduce the acidity of the citrus pomace and replace the existing method for adding quick lime to carry out deacidification, calcification and alkalization of soil are effectively prevented, the content of the compound fertilizer is more than 55%, the pH value is 6.5-8.5, the total contents of N, P and K are more than or equal to 8%, the water content is less than or equal to 20%, the contents of trace elements such as B, Zn and Mg are rich, and the other quality indexes are superior to national standard of organic fertilizer respectively.

An endovascular device includes a body having a surface, and at least one protein or peptide antagonist of calcification disposed on a portion of the surface. In another embodiment of the invention, an endoluminal device includes a body having a surface, and a coating disposed on a portion of the surface. The coating includes a transforming growth factor beta receptor antagonist. Another embodiment of the invention provides a method of inhibiting calcification of an endoluminal device. The method includes providing a body including a surface, disposing at least one protein or peptide antagonist of calcification on a portion of the surface, and deploying the body at a treatment site.

Inhibitors of bone calcium resorption are administered to allow high doses of vitamin D compounds or mimetics to be given with the intent of treating non-calcium related diseases such as cancer, psoriasis, and autoimmune disease without the dangers of calcification of kidney, heart, and aorta. Inhibitors of bone calcium resorption include the bis-phosphonates, OPG (osteoprotegerin) or the soluble RANKL (receptor activator of NF-κB ligand) receptor known as sRANK (soluble RANK which is the protein expressed by the NF-κB gene), and function to block the availability of calcium from bone thereby preventing hypercalcemia and the resulting calcification of soft tissues. Thus, high doses of 1α,25-dihydroxyvitamin D₃ (1,25-(OH)₂D₃), its analogs, prodrugs, or mimetics can be utilized with minimal risk to a patient. Specifically, alendronate is shown to block the bone calcium mobilization activity of both 1,25-(OH)₂D₃ and its very potent analog, 2-methylene -19-nor-(20S)-1α,25-dihydroxyvitamin D_3.

The invention discloses an orange peel dregs seedling raising substrate and a preparation method thereof, and belongs to the technical field of preparation of seedling raising substrates. Fermented orange peel dregs subjected to microorganism fermentation de-acidification, composite enzyme preparation degradation and microorganism liquid bacterial agent composting fermentation are used as a raw material; shaximiao group purple soil is used for replacing non-renewable resources such as turf, perlite, and vermiculite to scientifically compound a soil insecticide so as to obtain the seedling raising substrate which is free of weeds and pests, good in physical property, reasonable in hygroscopicity, excellent in air-conductivity, reasonable in PH value, strong in ion exchange capacity, balanced in nutrition, high in seedling emerging rate, and regular and strong in seedlings. The preparation method disclosed by the invention is simple in process and low in requirement on equipment, the orange peel dregs are fermented for 12-15 days, the pest killing and sterilization of the seedling raising substrate is 5-7 days at most, the preparation method saves 18-20 days as compared with the prior art, not only is the raw material cost of the seedling raising substrate greatly lowered, but also the production period is shortened, and the preparation method is not restricted by factors such as weather, and can achieve mass production at any time.

The invention relates to the technical field of environment control, in particular to a method for clearing moss in water. The method for clearing the moss in the water comprises the following steps of 1, preparing of drugs: respectively preparing a certain amount of calcium peroxide, chlorine dioxide disinfectant and acetic acid, and crushing the calcium peroxide powder to certain mesh; 2, feeding of drugs: feeding the prepared calcium peroxide into a water body containing the toss, enabling the calcium peroxide to react in water for a period of time, feeding the prepared chlorine dioxide disinfectant, enabling the chlorine dioxide disinfectant to react in water for a period of time, feeding the prepared acetic acid, and enabling the acetic acid to react in water for a period of time, wherein the certain drug feeding frequency is controlled, and the daily feeding frequency is controlled. The method has the advantages that the moss in the water body can be quickly and effectively cleared, the environment-friendly effect is realized, and the operation is easy.

The invention discloses an integrated biological synchronous denitrification and decalcification device for wastewater and a method of the device. The device comprises a water distribution area, a chemical calcium removal area, a biological denitrification area and a separation area, wherein a microporous aeration system covers the bottom of the water distribution area, and a water inlet pipe anda return pipe are arranged on the side wall; the chemical calcium removal area is filled with quartz sand particles, and the quartz sand particle layer is covered with denitrifying granular sludge; asand inlet pipe is arranged at the top of the chemical calcium removal area, and a sand discharging pipe is arranged at the bottom of the chemical calcium removal area; a sludge inlet pipe is arrangedat the top of the biological denitrification area, and a sludge discharging pipe is arranged at the bottom; an overflow groove and a water outlet pipe are sequentially arranged on the side wall of the separation area from bottom to top; water in one path of the water outlet pipe flows back into the device through the return pipe, and water in the other path is discharged. A three-phase separatoris arranged in the center of the separation area, and a gas collection connecting pipe and an exhaust pipe are arranged at the upper part. According to the device and the method, wastewater biologicaldenitrification and chemical precipitation calcium removal processes are coupled, the integrated wastewater biological denitrification and calcium removal device can be constructed on the basis of aheterotrophic denitrification reaction in combination with a chemical precipitation process, and synchronous denitrification and calcium removal can be realized in the same reactor.

The invention provides a fermenting hydrogen-producing bacterium and a method of preventing calcification of activated sludge. The fermenting hydrogen-producing bacterium is collected under CCTCC M 2018077. By adding the fermenting hydrogen-producing bacterium into a wastewater anaerobic fermentation treatment system in the presence of activated sludge, the activated sludge is enhanced, the gas-producing capacity of the activated sludge is improved, and activated sludge acidification and activated sludge calcification preventing are achieved. Experiments prove that the fermenting hydrogen-producing bacterium enhances the activated sludge reaction system, the gas yield is increased by 15.2%, and highest daily gas yield is increased by 47%, which shows that the fermenting hydrogen-producingbacterium (DW01 strain) has significant influence on biogas production of anaerobic particulate sludge in enhanced stable stage, and activated sludge calcification is positively prevented.

The invention discloses a support-less artificial bio-prosthetic valve, which comprises an inner lining tube, three pieces of valve leaves and an outer lining tube, the inner lining tube wall is provided with three narrow slit with a shape of approximately semi-circular arc on the circumferential circle, the lower margins of the three valve leaves are arranged between the inner lining tube and the outer lined backing sheet along the three narrow slits, the closing threads sews the inner lining tube, the peripheral portions of the three valve leaves and the outer lined backing sheet along the margin of the inner lining narrow slit, the inner lining tube and the outer lined backing tube extend to the two ends, thus forming the upper and lower tunnels for the support-less valve. The invention solves the problem in the prior art that the valve leaves are fixed only by closing threads, higher security for the valve leaves are achieved, early calcification of the valve leaves and the inner lining tube can be prevented effectively, the long-term follow-up results for the patients can be improved substantially.

A nozzle device and method for creating a fluid nucleation in situ, is disclosed. The nozzle has a housing having a hollow interior, an outer cylindrical wall, and inlet and an outlet, and a diffuser disposed in the cylindrical tube at a first end toward the inlet. The diffuser is configured to break bonds between adjoining fluid molecules and create a nucleation event. The nozzle further has a mesh framework disposed in the cylindrical tube and extending longitudinally within the tube in the nucleation zone, and is configured to manipulate the bonding and un-bonding of water molecules within a pressurized environment for the production of snow, clean water or both.

The invention relates to a collagen cross-linker composition and an application thereof. The composition comprises a photosensitive cross-linker, a chemical cross-linker, citrate and imidazole. By using the cross-linker composition, the chemical crosslinking and photo-oxidation of decellularized collagen can be carried out simultaneously, and synergism is exerted, so that the efficiency of a cross-linking reaction is increased, and a cross-linked collagen medical material with higher quality is obtained.

The present invention is related to a composition comprising phytic acid or a phytate salt, magnesium in the form of salt, hydroxide or oxide and optionally at least one polyphenol. These components may be in isolated form or be part of an enriched plant extract. The invention is also related to the use of this composition for the treatment of renal lithiasis, preferably calcium or calcium oxalate lithiasis, either in the form of a medicament, a nutraceutical or functional food or food supplement.

The invention discloses composite fermentation microbial inoculant and an application of the composite fermentation microbial inoculant in preparation of a citrus pulp bio-organic fertilizer. The composite fermentation microbial inoculant includes fertilizer fermenting zymocyte, bacillus subtilis, enterococcus faecalis and trichoderma. The composite fermentation microbial inoculant can ferment organic waste having a main raw material of citrus pulp to obtain the biological organic fertilizer. A preparation method of the citrus pulp bio-organic fertilizer provided by the invention is simple inoperation, low in operation cost, good in product effect, can be promoted and applied on a large scale, can not only realize harmless treatment of the citrus pulp, solve environmental pollution problems, but also realize the recycling of the agricultural waste, and has good economic and ecological benefits; and the conventional nutrient indicators of the obtained bio-organic fertilizer meets the standards of Bio-Organic Fertilizer Standards of ''Agricultural Industry Standards of the People's Republic of China (NY 525-2012)'', and the bio-organic fertilizer is rich in nutrients, and can effectively improve soil, promote plant growth, enhance plant disease resistance, and improve the quality of agricultural products.

The invention relates to a composite microbial agent and an application thereof in regulating and controlling the pH value of pit mud, and belongs to the technical field of biology and the technical field of fermentation. The invention provides a composite microbial agent. The composite microbial agent comprises composite microorganisms and yellow water; and the composite microorganisms comprise composite acetic acid utilization bacteria, comprise lactic acid utilization bacteria, comprise nitrate reducing bacteria, comprise actinomycetes and comprise sulfate reducing bacteria. The method disclosed by the invention follows the pit micro-ecological principle, and a variety of microorganisms such as the acetic acid utilization bacteria, the reducing bacteria, the actinomycetes and the lacticacid utilization bacteria are selected and combined for use to construct benign pit micro-ecology. The composite microbial agent provided by the invention can regulate the pH value of pit mud, so that the pH value of the pit mud is maintained at the optimal state of 6.0-6.8, aging of the pit mud is relieved, and the micro-ecological structure in the pit mud is stabilized.

The invention provides a high induced activity repairing material and a preparation method and application thereof. The repairing material is a natural polymer material having a 3D network-like porous structure. The repairing material has a three-layer structure composed of a middle layer and upper and lower surfaces. The middle layer contains collagen, a polysaccharide substance, an active factor and a growth factor. The upper and lower surfaces comprise collagen, a polysaccharide substance and an active factor. The repairing material can be degraded in vivo, can contain one or more growth factors such as a follicle inhibitory protein, a nerve growth factor, a platelet-derived growth factor, an epithelial growth factor and a matrix gamma-carboxyl glutamate protein, and can be used in myocardial, nerve, smooth muscle and epithelial tissue growth and regulation or prevent the post-implantation calcification of a matrix material without an immunogen.

The invention relates to a hot water unit (1) with a water line, comprising at least one water inflow (2), which leads from a wall connection (5) to the hot water unit (1), and at least one water outflow (3), which leads from the unit to a water discharge point (6), and at least one heating device (4) positioned between said water inflow (2) and water outflow (3), wherein the hot water unit (1) has, at its water inflow (2), at least one means for dosing (7) additives for chemically changing the water quality. The hot water unit (1) according to the invention is characterized in that at least one second means (10) for dosing additives for chemically changing the water quality is arranged in the water line. The hot water unit (1) according to the invention permits, in an effective manner and at low cost, a level of water quality which meets increased consumer demands, while the unit at the same time has a longer service life.

Disclosed is a domestic cooking appliance (1) comprising a cooking chamber wall (2) delimiting a cooking chamber (5), a fan impeller (10) in the cooking chamber (5), a baffle wall (12) which covers the fan impeller (10) in an air-permeable manner, and a steam inlet (19) that has at least one steam inlet port (20) which extends into the cooking chamber (5), in a region (14) between the cooking chamber wall (2) and the baffle wall (12). The invention can be used advantageously especially in an oven having a steam cooking function.

Methods and compositions for reducing, preventing or reducing the progression of calcification in peritoneal dialysis patients are provided. In an embodiment, the present disclosure provides a method comprising administering to a patient during peritoneal dialysis therapy a dialysis solution comprising a therapeutically effective amount of pyrophosphate ranging between about 30 [mu]M and about 400 [mu]M. Formulations of dialysis solutions according to the dose ranges claimed in the present disclosure allow therapeutic amounts of pyrophosphate to be delivered to peritoneal dialysis patients.