The invention relates to a counter for metal nano particles in solution, which is used for measuring relative concentration of metal nano particles in solution. The counter comprises a laser, a neutral attenuator, a beam expanding lens, a cover glass or a sample cell, a micro objective, a dichroic mirror, a lens, a pinhole, a single photon detector, a data collection card and a computer. Sample solution is placed on the cover glass or on the sample cell, the laser irradiates the metal nano particles in the solution, the produced scattered light is focused on the pinhole by the lens after being collected by the objective lens and the pinhole is coupled with the single photon detector. Signals generated by the single photon detector are output by the computer via the data collection card. The operating principle of the invention is based on a very small laser confocal irradiation micro-area (-10 litre), photon burst occurs when the metal particles enter or leave the micro-area due to Brownian movement, the number of the photon burst is proportional to concentration thereof. The counter of the invention can be applied to researches and clinical detection in fields such as biomedicine, chemistry, physics and the like.