208results about How to "Simplify preparation" patented technology

Targeted therapeutics that localize to a specific subcellular compartment such as the lysosome are provided. The targeted therapeutics include a therapeutic agent and a targeting moiety that binds a receptor on an exterior surface of the cell, permitting proper subcellular localization of the targeted therapeutic upon internalization of the receptor. Nucleic acids, cells, and methods relating to the practice of the invention are also provided.

The present invention provides for compositions and methods for the preservation of tissues and organs ex vivo and in situ. In addition, the present invention provides for kits that may be used in the preparation of the solutions of the present invention. The present invention also provides a device for perfusing tissues and organs with the solutions of the present invention.

Polyether polyols with an OH number of from 15 to 120 mg of KOH / g are produced by (i) introducing a mixture of DMC catalyst and a poly(oxyalkylene)polyol or a mixture of DMC catalyst and a polyether polyol (“heel”) obtainable by the process according to the invention is initially into a reactor and (ii) continuously introducing one (or more) low molecular weight starter compound(s) with a (mixed) hydroxyl functionality of from 2.2 to 6.0 and a mixture composed of a) 73 to 80 parts by weight (per 100 parts by weight of a) plus b)) of ethylene oxide and b) 27 to 20 parts by weight (per 100 parts by weight of a) plus b)) of at least one substituted alkylene oxide corresponding to a specified formula into the mixture from step (i). These polyether polyols are particularly useful for the production of flexible polyurethane foams.

Disclosed are pharmaceutical compositions, particularly oral dosage forms, which comprise two or more enteric coating materials, either as a coating or as part of a matrix dosage form, and methods of making and using the same. The compositions are characterized by having a sustained release profile at lower pH and an accelerated dissolution profile at higher pH.

The present invention relates to a method for treating acutely or chronically injured soft tissue in an animal or human, the method comprising administering a therapeutically effective amount of HA around the injured soft tissue. The method is useful for the treatment of sprain, strain and shin splints in an animal or human by periarticular administration of a composition comprising HA and a pharmaceutically acceptable carrier. The present invention can be used to potentiate the concomitant treatment of sprain or strain with other therapies.

An electrophoretic display medium and preparing method thereof. The electrophoretic display medium comprises: negatively or positively-charged pigment particles; neutral pigment particles with colors different from the charged pigment particles; and low-polar and / or non-polar dispersing solvent. The method of preparing the electrophoretic display medium comprises: synthesizing neutral pigment particles; synthesizing charged pigment particles; and preparing electrophoretic display medium. The method of synthesizing the neutral pigment particles comprises: mixing together pigment particles, macromonomers, coupling-agents and chain-initiators for polymeric reaction in the solvent, and reacting at a temperature of 30-120° C. for 4-48 hours. The method is applied to many kinds of inorganic oxides, inorganic salts and complex inorganic salt pigments. This method fundamentally avoids agglomeration caused by attraction of positively and negatively-charged electrophoretic particles, greatly enhancing display performance. The steps of synthesizing particles are simple and the preparing procedure of the electrophoretic medium is simplified, making the whole process simple and highly efficient.

The invention discloses a thin-wall high temperature alloy tubing simulation extrusion device, belonging to tubing thermal-extrusion field. The device comprises a standard die set with a guiding device, and a simulation tubing thermal-extrusion mould which is arranged on the standard die set with the guiding device, the standard die set comprises an upper die holder, a lower die holder, a guide pillar and a guide bush, one end of the guide bush is connected with the upper die holder, the guide post is connected with the lower die holder, and the other end of the guide post is sheathed in the guide bush and can move along the guide bush up and down. The simulation tubing thermal-extrusion mould comprises an extrusion shaft, an extrusion needle, an extrusion pad, a positioning frame, an extrusion container inner lining, an extrusion container outer lining, a die cushion, a cushion block and an extrusion die. The device of the invention has good popularity; the guide post and the guide bush are adopted, the die cushion and the extrusion container have positioning ring coordination, the extrusion needle and the extrusion pad have guide coordination, good alignment, and convenient and flexible use; the time consumption of experimental process is short, the efficiency is high, the material use ratio is high and the cost is low.

The invention relates to a counterforce loading frame for a multifunctional self-balancing type continuous beam test. A longitudinal sliding groove is machined in the middle of the upper surface of a counterforce frame bottom plate. Electric hoisting devices, counterforce loading frame stand columns and distribution beam supports are arranged on the slide groove. Full threads are machined in the counterforce loading frame stand columns. Orientation wheels are arranged at the bottoms of the counterforce loading frame stand columns. Lower beams are arranged on the tops of the counterforce loading frame stand columns through screw thread fit. Middle beams and upper beams are fixedly arranged on beam stand columns through nuts. Test beams are arranged between the middle beams and the upper beams. Displacement monitoring device supports are arranged on the tops of the upper beams. Distribution beams are placed on the distribution beam supports. The two sides of the distribution beams are provided with rulers and slide grooves, wherein hooks are arranged on the slide grooves. Roller supports are located on the distribution beams. Jacks are arranged on the lower portions of the distribution beams. The counterforce loading frame is suitable for tests of continuous beams, simply supported beams and columnar components, and the span can be changed so that the counterforce loading frame can be used for components of different sizes.

A process for preparing a functionalized or unfunctionalized diene block copolymer comprising at least one polyether block of number-average molecular weight approximately from 150 to 5000 g / mol linked to at least one block constituted of a diene elastomer via at least one silicon atom. The process allows a high degree of grafting of the polyether to the polymer chains. Also disclosed is a reinforced rubber composition, especially intended for the manufacture of tires, comprising such a diene block copolymer which is intended to interact with the reinforcing filler. Such a rubber composition has improved hysteresis properties in the vulcanized state, while retaining satisfactory processing properties in the non-vulcanized state.

A high-accuracy geomagnetic vector measurement method is characterized in that a vertical additional magnetic field and a horizontal additional magnetic field which have the same intensity but different directions are added to the position of a probe of a high-accuracy total-field magnetometer; a geomagnetic field without additional magnetic fields and a resultant magnetic field with an additional forward magnetic field and an additional reversed magnetic field are measured respectively; and then, each component, including a vertical component Z, a horizontal component H, a geomagnetic inclination I and a declination D, of a geomagnetic vector can be computed, and the method is suitable for fast and high-accuracy geomagnetic vector measurement outdoors or in a fixed station. According to the method, the geomagnetic vector measuring accuracy is in positive correlation with the accuracy of the matched magnetometer, and the high-accuracy total-field magnetometer is superior to a fluxgate three-component magnetometer with 10 nT of measuring errors. A high-accuracy geomagnetic vector field measurement device comprises one group or two groups of field coils and a tripod, the field coils are added to the outside of the high-accuracy total-field magnetometer probe, and the field measurement device is matched with the high-accuracy total-field magnetometer and used for rapidly measuring each component of the geomagnetic vector outdoors or in the fixed station.

The present invention relates to substances, crosslinkable by attachment of an Si-bonded hydrogen atom to an aliphatic multiple bond, which comprise at least one compound of the formulaR3P(O)(OH)2  (III)and / or the derivatives thereof,R3 being an optionally substituted hydrocarbon radical which can be interrupted by heteroatoms.

The invention provides an accurate positioning and intelligent navigation method for an oral implanting robot. The method comprises the following steps: (1) planning a digital tooth implanting scheme;(2) designing a personalized fixing structure of a positioning marker; (3) designing a standard positioning bracket of the positioning marker; (4) generating the positioning marker; (5) acquiring position coordinates of an implant in a three-dimensional implanting scheme; (6) constructing an oral collision model; (7) constructing and correcting an actual scene coordinate system; (8) planning a motion path of the robot and performing offline programming; and (9) performing implanting operation of the robot. According to the method, accurate calculation of target position coordinates of an endeffector of the robot in a global coordinate system in the three-dimensional implanting scheme is realized before an operation, the precision of an optical positioning and navigation system is corrected by utilizing contact position feedback of the robot, and the collision model of the end effector of the implanting operation and dynamic planning of the motion of the robot are constructed.

A device is disclosed for applying individual reinforcing threads onto a tubular layer. The device contains a positioning ring with equidistant holes that lie on a circumferential line, with the positioning ring surrounding and concentric with a rotationally symmetric, funnel-shaped deflection element. The deflection element deflects the reinforcing threads that are guided from radially outward to radially inward through the holes f the positioning ring into an essentially axial direction, wherein all the threads assume an equidistant spacing from one another. Also disclosed is a process for manufacturing an unfinished tube consisting of several layers with the aid of the device.

Improved needle free injectors comprising of a energy sources, triggering mechanisms, impact members, and drug delivery pistons are disclosed. In one preferred embodiment, the triggering mechanism comprises a spool which seals an energy source comprised of compressed gas and a component for releasing the spool to release the pressurized gas and urge a ram forward to force a drug containing formulation through a drug delivery orifice. The device may include a cap covering the orifice and safety mechanisms to prevent accidental delivery

A porous lithium manganese phosphate-carbon composite material, and a preparation and application thereof. Multiple nano-pores are distributed in the composite material, and the composite material includes a lithium manganese phosphate material and carbon. The method for preparing the porous lithium manganese phosphate-carbon composite material includes the steps of: mixing a porous pyrophosphate material with a doped metal source, a lithium source, phosphate and a carbon source and then drying them to obtain a reaction precursor, and calcining the reaction precursor at a constant temperature under a protective atmosphere to obtain the composite material. The lithium manganese phosphate material contains compounds in a general formula of LiMnxM1−xPO4, and the porous pyrophosphate material contains compounds in a general formula of (MnxM1−x)2P2O7 and 0 wt % to 50 wt % of carbon, where M comprises a transition metal, and 0.6≦x≦1.

The invention relates to a method for measuring service quality, and network equipment and a network system thereof, wherein, the method comprises the steps that: received sender reporting RTCP SR messages in a real-time control protocol is transmitted to a second measuring point by a first measuring point; receiver reporting extra RTCP RR messages in an extra real-time control protocol transmitted by the second measuring point is received; and the QoS parameters between the local site and the second measuring point are calculated by the first measuring point according to the extra RTCP RR messages. The network equipment comprises a message generating unit and a second message transmitting unit; the network system comprises the first network equipment comprising a first message transmitting unit, a message receiving unit and a network segment service quality calculating unit; and the second network equipment comprises a message generating unit and the second message transmitting unit. The invention can realize the service quality measurement based on the network segments under the situation that the network burden is not increased.

The present invention discloses an apparatus for thin-layer cell smear preparation and in-situ hybridization, comprising at least one positioning device and a sealing device. The positioning device comprises at least one first opening. When the positioning device is set on a carrier device, the wall of the first opening and the carrier device form a cavity. The cavity is used to accommodate a cell suspension. The sealing device is provided on the positioning device for sealing the cavity to form an enclosed space.

The invention belongs to the technical field of grinding equipment, and particularly discloses a gearbox grinding device. The gearbox grinding device comprises a workbench. A grinding box is arrangedon the workbench. A lifting air cylinder is arranged on the top wall of the grinding box. A motor is connected to the end of a piston rod of the lifting air cylinder. An output shaft of the motor is connected with a grinding disc. A first air cylinder and a second air cylinder are arranged on the workbench, and clamping discs are arranged on piston rods of the two air cylinders. The lifting air cylinder, the first air cylinder and the second air cylinder communicate with air pipes. A rodless cavity of the lifting air cylinder is connected with a first air pump. A second air pump is further included. A bidirectional valve is arranged at the air outlet end of the second air pump. Two branch pipes communicating with the first air cylinder and the second air cylinder correspondingly are connected to the bidirectional valve. Dust blowing pipes are arranged in the first air cylinder and the second air cylinder, and an electric valve is arranged in each dust blowing pipe. The air outlet endsof the dust blowing pipes are located below the grinding disc. A sliding plate is in sliding connection to the workbench and is located below the grinding disc. According to the scheme, automatic grinding of a gearbox is achieved, and meanwhile grinding dust can be treated.

The invention provides a method and device for high-accuracy field measurement of terrestrial magnetism vectors. A tripod, a perpendicular coil and a total field magnetometer are utilized to measure a synthesized magnetic field value T-1 and a synthesized magnetic field value T-2 of a normal terrestrial magnetic field To without an additional magnetic field, a perpendicularly-upward magnetic field Tf additionally arranged for a terrestrial magnetic field and a double perpendicularly-upward magnetic field 2Tf additionally arranged for the terrestrial magnetic field, and please see the specification for the expression of the calculation formula; a horizontal coil is arranged, the geometric center of the perpendicular coil and the geometric center of the horizontal coil are made to coincide with each other, the total field magnetometer is utilized to measure a synthesized magnetic field value T+ / / and a synthesized magnetic field value T- / / after a horizontal forward magnetic field and a horizontal reversed magnetic field are additionally arranged for the terrestrial magnetic field, a terrestrial magnetism declination is calculated, and please see the specification for the expression of the calculation formula, wherein DO is equal to the value of the included angle between the axis of the horizontal coil and the geographical north direction and is a known preset value. Only the coils need to be horizontally adjusted before observation, and the method and device are suitable for large-area rapid measurement in geophysical exploration field general survey operation.

The invention discloses a recognition method and device based on a video and an electronic equipment identification and a video monitoring system, and relates to the technical field of video monitoring. The method comprises the following steps of acquiring video image information acquired by a monitoring device and a first time label corresponding to the video image information; acquiring electronic equipment identification information acquired by identity identification acquisition equipment and a second time label corresponding to the electronic equipment identification information; associating the video image information with the electronic equipment identification information according to the first time label and the second time label; and recognizing and tracing a target object basedon the associated video image information and the electronic equipment identification information. According to the method, the device and the video monitoring system, the preparation work for association of the video image information and the electronic equipment identification information is simplified, the rapid calling of a video image and electronic identity label information is realized, therecognition efficiency and accuracy can be improved, and the powerful help can be provided for public security officers, criminal investigators and the like.

The present invention discloses a vehicle speed measuring method, a vehicle speed measuring device, a vehicle speed measuring system, an electronic device and a storage medium and belongs to the fieldof speed measuring technologies. With the vehicle speed measuring method, the vehicle speed measuring device, the vehicle speed measuring system, the electronic device and the storage medium adopted,the speeds of vehicles can be measured more conveniently. The vehicle speed measuring method includes the following steps that: the first original image position coordinate value of a specified position of a vehicle to be measured in one frame of video image and the second original image position coordinate value of the specified position of the vehicle to be measured in the other frame of videoimage are acquired; the first original image position coordinate value and the second original image position coordinate value are inputted into a pre-established mapping model, so that a corresponding first physical position coordinate value and second physical position coordinate value are obtained; the actual moving distance of the vehicle to be measured is determined according to the first physical position coordinate value and the second physical position coordinate value; and the speed of the vehicle to be measured is determined according to the actual moving distance of the vehicle to be measured and interval time between the one frame of video image and the other frame of video image. The vehicle speed measuring method, the vehicle speed measuring device, the vehicle speed measuring system, the electronic device and the storage medium of the invention are applied to vehicle speed measurement.

A method for producing Ac-225 is presented, wherein Ac-225 is produced by bombardment of Th-232 with hydrogen isotope nuclei accelerated in a cyclotron. The method, which allows production of Ac-225 at high yields and purity levels, is particularly interesting for the supply or Ac-225 or of the daughter Bi-213 for medical applications.

A method for cleaning and drying a front and a back surface of a substrate is provided. The method includes brush scrubbing the back surface of the substrate using a brush scrubbing fluid chemistry. The method further includes applying a front meniscus onto the front surface of the substrate upon completing the brush scrubbing of the back surface. The front meniscus includes a front cleaning chemistry that is chemically compatible with the brush scrubbing fluid chemistry.

The invention discloses a thick plate joint welding method, which adopts an electroslag welding process to weld two workpieces which are 240 to 286 millimeters thick into a whole and comprises the following: 1, a first step of preparation before welding, which is to prepare a powder material by adding a plurality kinds of iron alloy elements into formula of a pipe coating, prepare the pipe coating by adding adhesive into the powder material after uniformly mixing, coat the pipe coating on the outer walls of pipe poles, fix and mount four pipe poles on a clamping mechanism and regulate the mounting gap between two workpieces; 2, a step of welding, which is to perform electroslag welding by delivering a welding stick into a weld pool formed by the four pipe poles, energize the welding stick and weld the pipe poles, wherein the welding direction is form a lower bevel to an upper bevel; and 3, a step of heat treatment after welding. The thick plate joint welding method has the advantages of high simplicity, convenience and efficiency, high implementability, great improvement on production efficiency and reduction in production cost. When the method is used, the working environment of operators is improved, dust and arc light damage is relieved, and environment is better protected.

An artificial stone wall panel comprises: an artificial stone, composition of which comprises an inorganic fine powder component with a size of from 9.5 mm to 180 μm, an inorganic finely divided component with a size of less than 180 μm, and a resin component in an amount of from 7 to 30% by weight based on a total artificial stone composition, with a weight ratio of the inorganic fine powder component to the inorganic finely divided component (inorganic fine powder component:inorganic finely divided component) being in a range of from 1:1 to 5:1; and a support for installing the artificial stone onto a wall surface, embedded in the artificial stone, wherein part of the support is exposed at a back surface or edge surface of the artificial stone. This artificial stone wall panel is realized by mold-integrating an artificial stone and structure for installing such artificial stone to an external wall surface, and may be used as an external wall material with excellent design having clear contrast and natural texture.

The invention provides a coating device. The coating device comprises a die coater (5) equipped in a way to face towards a conveying wire (10) for conveying feeding materials (2) and having a pair of slit-shaped outlets (6a, 6b) and a pair of inlets (7a, 7b) respectively communicated with the outlets; a first supplying part (40) supplying a first liquid (8) for forming adhesive to one (7a) of the inlets; and a second supplying part (60) supplying a second liquid (9) for forming adhesive by contacting with the first liquid to the other inlet (7b), wherein, the pair of outlets of the die coater is separately equipped along the feeding material conveying direction A of the conveying wire (10) and located adjacent to each other. The first liquid and the second liquid immediately contact with each other after discharged respectively from an outlet. Therefore, the coating device can easily perform preparation work and keep the coating face smooth when laminated products are manufactured through two-liquid solidifying type solvent-free adhesive.

The invention discloses a perovskite solar cell and a method of fabrication thereof. The perovskite solar cell sequentially comprises a transparent electrode, a mesoporous P-I-N framework and a counter electrode from the bottom to top; the mesoporous P-I-N framework is composed of an n-type semiconductor layer, an insulating layer, and a p-type semiconductor layer in a sequentially stacked mode, and the n-type semiconductor layer, the insulating layer and the p-type semiconductor layer all comprise mesopores filled with a perovskite material. The preparation method sequentially includes preparing the mesoporous P-I-N framework on a transparent conductive substrate through a spin-coating method or a screen printing method, filling with the perovskite material and preparing the counter electrode layer.

The invention relates to a polyester glass fiber geotextile and a production method thereof. The geotextile is prepared by uniformly mixing glass fibers and polyester fibers, bonding with a bonding agent and pressing, wherein the weight part ratio of the glass fibers to the polyester fibers to the bonding agent is (5-7):(2.5-4.0):(0.5-1). The production method of the polyester glass fiber geotextile comprises the following steps of: preparing glass fibers and polyester fibers according to the weight part ratio; opening and mixing; carding, molding and feeding into a conveying mesh belt; bonding; heating; performing cold rolling; cooling; and winding, wherein the bonding treatment comprises spreading treatment and permeating treatment. The polyester glass fiber geotextile has the advantages of uniform fiber distribution, high breaking strength, high breaking elongation consistence, remarkable waterproofing function and suitability for road surfaces; and by adopting a dry production method, water resource is saved, drainage of waste water is avoided, environmental pollution is avoided, bonding agent mixing equipment used in conventional production is eliminated, and the equipment investment is low.

A method for cleaning and drying a front and a back surface of a substrate is provided. The method includes brush scrubbing the back surface of the substrate using a brush scrubbing fluid chemistry. The method further includes applying a front meniscus onto the front surface of the substrate upon completing the brush scrubbing of the back surface. The front meniscus includes a front cleaning chemistry that is chemically compatible with the brush scrubbing fluid chemistry.