The invention discloses a DISA vertical green molding sand molding line air cylinder mold and a casting process thereof. The mold comprises a forward pressing plate, a reverse pressing plate, anti-collision columns and positioning pin bushes, wherein the forward pressing plate and the reverse pressing plate are both provided with pouring gate cups, the tail end of a horizontal runner is provided with a horizontal runner riser, the forward pressing plate and the reverse pressing plate are both provided with a plurality of feeding risers, the lower portions of the feeding risers are provided with vertical pouring gates, the two sides of the vertical pouring gates of the forward pressing plate and the reverse pressing plate are both provided with mold core mold cavities, the two ends of the vertical pouring gates of the forward pressing plate are provided with pouring gates, the pouring gates communicate with the mold core mold cavities of the forward pressing plate horizontally, the topsof the mold core mold cavities of the forward pressing plate are provided with air exhaust pieces, and the air exhaust pieces communicate with air exhaust passages. The casting process comprises themolding working procedure, the smelting working procedure, the nucleating working procedure, the pouring working procedure, the shakeout working procedure, mechanical property detection, primary shotblasting, external cooperation polishing, secondary shot blasting, inspecting packing and warehousing. By means of the DISA vertical green molding sand molding line air cylinder mold and the casting process thereof, the problems of casting shrinkage cavities and shrinkage porosity, weight reducing hole fleshiness and sand sticking and the like are solved, the casting finished product rate and theprocess production rate are greatly increased, and the mass production requirements are met.