The invention provides a processing method for a TC4 titanium alloy spiral groove screw tap. The method comprises the working procedures of blanking, rough turning, finish turning, milling, benching, heat treatment, grit blasting, surface treatment, external grinding working procedure, thread grinding, cutter grinding, relief grinding, laser carving, and the like. In the thread grinding working procedure, a tail of a spiral groove is used as a grinding benchmark, threads are at least fed for three times to grinding and processing, the threads are relief grinded to meet the requirement, and annealing is strictly prevented; in the relief grinding working procedure, different relief grinding manners are adopted according to the actual demands of the production, one manner is that a 0.5-1mm of allowance is kept during relief grinding of a dorsal horn, and another manner is that only the about 0.1mm of allowance is kept during relief grinding of the dorsal horn. Through the adoption of the method disclosed by the invention, the accuracy requirement of the spiral groove screw tap based on the TC4 titanium alloy materials can be effectively ensured, the production efficiency is greatly improved, and even more, the processing problem that a spiral tooth back is a curve tooth surface is perfectly solved.