6 results about "Post operative pain" patented technology

The present application relates to the technical field of medical image analysis, in particular to a patient post-anesthesia pain grading evaluation method based on artificial intelligence. The method acquires multi-time body posture images in a complete respiratory cycle, constructs a trunk reference system, defines the end of the limb as an analysis point and a preset defense position as a target point; constructs a limb scheduling consumption matrix based on the distance between the analysis point and the target point, calculates the limb wandering confusion degree combined with the element distribution, and fuses to obtain the defense intention focus degree reflecting the order of whole body movement; the consumption matrix is subjected to geometric cost matching to obtain a limb scheduling total consumption index, and the focus degree is combined to generate a defense interference index; finally, the grading evaluation coefficient is determined according to the numerical distribution and stability of the index in the complete respiratory cycle, thereby objectively distinguishing the pain state and the wake-up period agitation state, and significantly improving the automation level and reliability of post-anesthesia pain evaluation.

This disclosure relates to drug releasing implants. In certain embodiments, the implants release drugs from a biodegradable material. In certain embodiments, the implant is a low swelling hydrogel. In certain embodiments, the drug is an analgesic, an anti-inflammatory agent, anti-bacterial or other anti-microbial agent. In certain embodiments, this disclosure relates to methods of providing an implant as reported herein at a surgical site or site of injury for uses in reducing post operative pain and inflammation.

The analgesic dressing is prepared from vinegar frankincense, radix angelicae sinensis, myrrh, radix angelicae, cortex cinnamomi, mint and normal saline, 4 g of vinegar frankincense, 10 g of radix angelicae sinensis, 10 g of myrrh, 10 g of radix angelicae and 10 g of cortex cinnamomi are selected to be mixed and beaten into powder during each modulation, 2 g of mint is independently beaten into powder, then a proper amount of normal saline is taken and stirred to be sticky, and the analgesic dressing is prepared. The analgesic dressing associated assembly comprises a one-way breathable film, the one-way breathable film is of a rectangular structure, arc chamfers are arranged at the corners of the one-way breathable film, the one-way breathable film is provided with a face A and a face B, a plurality of breathable holes are distributed in the face A in an array mode, the face B is connected with an isolation layer through glue, and oval holes are formed in the inner side of the one-way breathable film. A dressing placing assembly is connected to the side, on the A face, of the oval hole, and an anti-tearing protection gasket is arranged on the outer side, on the A face, of the oval hole. By filling the analgesic dressing, the postoperative pain of a patient can be greatly relieved, and meanwhile the pain caused by dressing changing can be relieved.

The present invention involves a method of treating pain. The method treats a patient having post-operative pain or chemotherapy induced neuropathic pain, and it involves a) assessing the patient to determine if they are experiencing post-operative pain or chemotherapy induced neuropathic pain, and if such pain is diagnosed; b) administering to the patient a therapeutically effective amount of an agonist for the nuclear receptor subfamily 4, group A, member 1 (NR4A1). In one embodiment, the agonist is selected from the group consisting of Cytosporone B, Ethyl 2-[2,3,4-trimethoxy-6-(1-octanoyl)-phenyl] acetate (TMPA), 1,3,7-trihydroxy-2,4-diprenylxanthone (CCE9), 1-(3,4,5-trihydroxyphenyl)-nonan-1-one (THPN), DIM-C-pPhOCH3 (C-DIM-5), 1,1-bis(3′-indolyl)-1-(phenyl)methane (DIM-C-Ph) and 1,1-bis(3′-indolyl)-1-(p-anisyl)methane (DIM-C-pPhOCH3).

The present invention relates to the field of image analysis technology, and specifically to a method for assessing post-anesthesia pain in combination with a patient's facial expression. The optical flow method is used to analyze the pixel movement of facial images, obtain optical flow vectors and information points, and quantitatively capture changes in facial expressions. In view of the differences in the effectiveness of information points, facial feature points are screened to reduce data redundancy. Taking into account the differences in the facial structures of patients, the pulling characteristics of the optical flow vectors are analyzed to determine the pulling direction of the image block. Painful expressions, such as closed eyes and eyebrows, can be characterized by the pulling direction. By analyzing the chaos and differences in the distribution of pulling directions, a facial pain index is determined, providing an accurate reference for pain assessment. Finally, based on a data set of facial images of multiple patients and pain index screening, a neural network is trained to establish a mapping relationship between facial expression and pain degree. This method not only improves the accuracy of pain assessment, but also significantly improves the evaluation efficiency, thereby realizing automated pain assessment of facial images of patients to be tested.

The present invention relates to an angiotensin II receptor antagonist and use thereof for preventing or treating acute pain, such as mechanical traumatic pain, in particular acute post-operative pain. Specifically, the present invention provides a compound of formula (IV), or a pharmaceutically acceptable salt, ester, stereoisomer, polymorph, solvate, N-oxide, isotopic label, metabolite, or prodrug thereof, and use thereof for preventing or treating acute pain, such as mechanical traumatic pain, in particular acute post-operative pain, preferably post-operative surgical incision pain.