The invention relates to a preparation for preventing electronic smoke. The preparation is prepared from the following raw materials in parts by weight: 30 parts of jasminum cinnamomifolium, 30 parts of houttuynia cordata, 30 parts of radix polygonati officinalis, 27 parts of fruits of Chinese wolfberry, 27 parts of golden cypress, 27 parts of gardenia, 25 parts of perilla leaves, 25 parts of duckweeds, 25 parts of loquat leaves, 25 parts of white atractylodes rhizome, 20 parts of radix curcumae, 20 parts of myrrh, 20 parts of frankincense, 20 parts of cassia seeds, 18 parts of honeysuckle, 18 parts of salviae miltiorrhizae, 18 parts of purslane, 15 parts of bidens bipinnata, 15 parts of coix seeds, 15 parts of hedyotis diffusa, 10 parts of dandelions, 10 parts of fructus schizandrae, 10 parts of root barks of white mulberry, 8 parts of spina gleditsiae and 5 parts of schizonepeta. The preparation has a radiation protection effect and a radiation damage adjuvant therapy effect; the adopted raw materials are common traditional Chinese medicines in China, widely distributed and low in price, so that the preparation has a wide application prospect.