The invention discloses a medicinal composition for curing gynecopathy and application thereof. The medicinal composition is prepared from spreading hedyotis herb, glabrous greenbrier rhizome, shinyleaf pricklyash root, common burreed rhizome (fried with vinegar), gordon euryale seed (fried), red paeony root, Chinese angelica, lightyellow sophora root, golden cypress, root of red-rooted salvia, Mongolian dandelion herb, cinnamomvine and safflower in a certain ratio, and according to a pharmaceutic conventional method, the medicinal composition can be prepared into clinically acceptable oral decoctions, pills, powder, capsules, tablets, particles, drop pills, soft capsules and oral solution. The medicinal composition has the advantages of quite good effects of curing gynecopathy such as cervical erosion, gynecological inflammation and urinary tract infection, high safety of clinical use, high cure rate, base strengthening of Chinese medicaments, less negative effects, safe and effective treatment under the instruction of doctors, and contribution to population.