The invention discloses a continuous casting type large-wall-thickness hot-rolled steel plate for deep sea pipelines and a production method thereof, and belongs to the technical field of pipeline steel. The hot-rolled steel plate is composed of, by weight, 0.03-0.06% of C, 0.15-0.30% of Si, 1.20-1.35% of Mn, smaller than or equal to 0.010% of P, smaller than or equal to 0.0012% of S, 0.01-0.05% of Alt, 0.03-0.05% of Nb, 0.00-0.05% of V, 0.005-0.016% of Ti, 0.25-0.40% of Ni, 0.00-0.30% of Cr, 0.00-0.20% of Cu, 0.00-0.15% of Mo and the balance Fe and inevitable impurity elements. Continuous castings with the thickness being 400 mm are adopted for producing the steel plate with the thickness being 41-48 mm. The steel plate and the production method thereof have the advantages that good metallographic structures are obtained, the Charpy impact toughness at -20 DEG C, the drop hammer toughness at -20 DEG C, the low yield ratio, the high uniform elongation rate, the anti-fracture toughness property CTOD, the A solution acid resistance HIC and SSCC, and the like of the large-wall-thickness hot-rolled steel plate for the deep sea pipelines are realized, and therefore the construction requirement of conveying pipelines of oil and gas fields of deep seas can be met.