The invention discloses a large-core-
diameter multimode
optical fiber PDT light diffuser based on a torsion-tapering-
etching composite structure, a preparation method and application, relates to the technical field of
optical fiber devices for
photodynamic therapy, and aims to solve the problems that in the prior art,
light field distribution is uneven,
wavelength adaptability is insufficient, and minimally invasive property and in-vivo stability are difficult to balance. According to the technical scheme, one end of a functional section is connected with a multimode
optical fiber body, and the other end of the functional section is sequentially provided with a torsion part, a
polishing and
etching part and a
tail end tapering part; a twisting-tapering-
etching composite structure design is adopted; multi-
mode coupling can be triggered when the optical
fiber is twisted by 30 degrees, a low-order mode is converted into a high-order mode, a
light field diffuses from the axis of the core layer to the edge, and a sufficient
light field basis is provided for lateral light emitting; the
tail end tapering changes the mode
effective refractive index by narrowing the core
diameter, more
axial transmission light is promoted to be converted into a leakage mode to be emitted from the side direction of the
conical surface, the total side light emitting power is improved through cooperation of the
tail end tapering and the leakage mode, and sufficient
light energy is provided for 630 nm PDT treatment.