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43results about How to "Improve specific recognition" patented technology
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Quantum dot-based electronic nose chip and design method thereof
ActiveCN109781947AImprove recognition accuracyQuality improvementMaterial analysisMicro nanoSensor array
The invention belongs to the technical field of semiconductor devices and integrated systems and discloses a quantum dot-based electronic nose chip and a design method thereof. The design method includes the following steps that: (1) a gas sensor array on the electronic nose chip is designed; and (2) a signal processing unit and a micro control unit are designed. The step (1) further includes thefollowing steps that: (1-1) with a quantum dot material adopted as an olfactory acceptor material, a quantum dot gas sensor unit is designed, specifically, a resistive or field effect transistor typesensor unit on a substrate is designed; and (1-2) a quantum dot sensor array of an MEMS or TFT device structure is designed based on the quantum dot gas sensor unit. According to the quantum dot-basedelectronic nose chip and the design method thereof of the invention adopted, the quantum dot material is adopted as the olfactory receptor material; the micro-nano gas sensor is designed and prepared; the sensor array is obtained on the basis of the MEMS and TFT device structure; and the MCU containing a pattern recognition algorithm, and the signal processing unit are integrated on the chip, andtherefore, the quantum dot-based electronic nose chip which has the advantages of high sensitivity , small size and low power consumption can be obtained.
Owner:HUAZHONG UNIV OF SCI & TECH
Rapid detecting sensor for microcystins
ActiveCN103698242AImprove specific recognitionImprove adsorption efficiencyWeighing by absorbing componentElectricitySpecific adsorption
The invention discloses a rapid detecting sensor for microcystins. The rapid detecting sensor utilizes a photochemistry polymerization method or an electrochemical polymerization method to synthesize a molecularly imprinted membrane, so that the combining capacity is improved, the delay time is reduced, and the specific adsorption capacity is strengthened; meanwhile, a Lamb wave piezoelectric membrane is utilized as an effector of the sensor, so that the sensitivity of the sensor is improved, the stability is increased, the cost is reduced, the performance of the sensor is strengthened, the trace detection of the microcystins is realized, and thus the rapid detecting method for the microcystins, with high sensitivity, rapidness, low cost and low operation requirements, is established.
Owner:SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
Specific nucleic acid aptamer and application
InactiveCN106929510ASmall molecular weightEasy to synthesizeMaterial analysisDNA/RNA fragmentationBacilliNucleotide
The invention provides sepecific nucleic acid aptamer. The nucleotide sequence of the specific nucleic acid aptamer is a sequence shown in the sequence table <400>1, the nucleic acid aptamer is screened through a whole bacterium reduction SELEX technique, is low in molecular weight and easy to synthesize and modify, can recognize enterohemorrhagic escherichia coli O157:H7 in a high-specific mode and be combined with the enterohemorrhagic escherichia coli O157:H7 in a high-affinity mode, does not specifically combined with other bacteria, can be used for detecting the enterohemorrhagic escherichia coli O157:H7 and has the important significant for effectively preventing and controlling infection of the enterohemorrhagic escherichia coli O157:H7.
Owner:INST OF HYGIENE & ENVIRONMENTAL MEDICINE PLA ACAD OF MILITARY MEDICAL
Piezoelectric detection sensor for microcystic toxins based on molecular imprinting technology
ActiveCN103760052AImprove specific recognitionImprove adsorption efficiencyMaterial weighingCompound aSpecific adsorption
The invention discloses a piezoelectric detection sensor for microcystic toxins based on a molecular imprinting technology. The piezoelectric detection sensor is characterized in that a photochemistry polymerization method or an electrochemical polymerization method is utilized to compound a molecularly imprinted membrane, so that the combining capacity is improved, the delay time is shortened, and the specific adsorption capacity is strengthened; meanwhile, a quartz crystal serves as an effective apparatus of the sensor, so that the sensitivity of the sensor is improved, the stability is increased, and the cost is reduced. The piezoelectric detection sensor provided by the invention has the advantages that the property of the sensor is improved, the trace detection of the microcystic toxins is realized, and the microcystic toxins detection method which is high in sensitivity, high in speed, low in cost, and low in operation requirement is established.
Owner:SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
Non-target screening analysis method for intoxicating organic pollutants in wastewater based on molecular network
PendingCN111562327AImprove concentrationReduce complexityComponent separationGeneral water supply conservationFraction CollectorMolecular network
The invention discloses a non-target screening analysis method for intoxicating organic pollutants in wastewater based on a molecular network. The method comprises the following steps of: a) carryingout solid-phase extraction on pretreated wastewater to obtain an organic pollutant concentrated solution; b) fractionating the organic pollutant concentrated solution by using a high performance liquid chromatograph equipped with an automatic fraction collector to obtain a to-be-detected fraction; c) analyzing and detecting the to-be-detected fraction in the step b) by adopting a high performanceliquid chromatography-time-of-flight mass spectrometer; and d) processing the mass spectrum data detected in the step c) by using open source analysis software, generating a molecular network associated with the organic pollutants, and analyzing substances of network nodes. According to the non-target screening analysis method for the intoxicating organic pollutants in the wastewater based on themolecular network, the pollutant molecular network is generated, the network nodes display the response intensity of the substance in different components in a pie chart form, and the concentrations of the same substance in different components can be visually compared.
Owner:NANJING UNIV
Dual-signal-amplification fluorescence sensor for detecting mercury ions and preparation method thereof
PendingCN111175268AImprove specific recognitionEnables ultra-sensitive detectionMicrobiological testing/measurementFluorescence/phosphorescenceMercuric ionSignal amplification
The invention discloses a dual-signal-amplification fluorescence sensor for detecting mercury ions and a preparation method thereof. The fluorescence sensor comprises seven probes, namely a, b, c andd, namely a probe S, a probe F, a probe F1, a probe F2, a probe IP, a probe H1 and a probe H2; fuel stimulation isothermal amplification (FSP) primary circulation is realized based on specific recognition (T- Hg<2+> -T specific base mismatch) of the mercury ions and nucleic acid, an F2 chain released by the FSP can achieve chain displacement catalytic card assembly reaction (CHA) with H1 and H2, secondary circulation is achieved, and lastly the mercury ions are detected through fluorescence signal enhancement. The fluorescence sensor is advantaged in that the sensor has low detection limit, high sensitivity, high reaction speed, strong anti-interference capability, mild reaction conditions and the like, can make up for defects of a mercury ion detection method in the prior art, and realizes rapid and accurate quantitative detection of the mercury ions.
Owner:MINJIANG UNIV
Optical detection sensor for microcystin
ActiveCN104345037AImprove specific recognitionImprove adsorption efficiencyPhase-affecting property measurementsColor/spectral properties measurementsMicrocystinSpectrum analyzer
The invention discloses an optical detection sensor for microcystin. The optical detection sensor comprises a linear polarization light source, a 45-degree / 45-degree / 90-degree glass prism, a sensing chip and a spectrum analyzer and is characterized in that a silicon circulation tank is arranged on the sensing chip; the sensing chip comprises a glass sheet, a gold layer coated on the surface of one side of the glass sheet as well as a microcystin molecularly imprinted membrane modified on the surface of the gold layer. The optical detection sensor disclosed by the invention has the beneficial effects that firstly, a molecular imprinting technique is adopted for forming a sensitive layer of the sensor, so that specific recognition and adsorption efficiency for the microcystin are enhanced, the specificity of detection means is improved, and the detection time is shortened; secondly, by the use of a surface plasma optical detection technology, the sensitivity is improved, and the performance of the sensor is improved; thirdly, the whole sensor is simple and quick to operate, is low in requirement on operators, and provides effective help for highly sensitive detection of the microcystin.
Owner:SUZHOU INST OF BIOMEDICAL ENG & TECH CHINESE ACADEMY OF SCI
Double-targeted compound, preparation method and application thereof
ActiveCN110075299AImprove specific recognitionImaging results are clearly identifiableOrganic chemistryPhotodynamic therapyMalignant Neoplastic DiseaseEgfr expression
The invention provides a compound, which is obtained by splicing a heptamethine cyanine structure and an epidermal growth factor receptor(EGFR) targeted drug molecular structure. The compound providedby the invention can be used as a hypoxia and EGFR double-targeted near infrared fluorescence probe, can realize the purpose of accurate imaging on malignant tumor lesions with high EGFR expression by targeting the tumor marker EGFR and the hypoxia state of tumor cells; in addition, the compound provided by the invention can be used as a photosensitizer for cancer treatment.
Owner:NINGBO HAIBO BIOTECHNOLOGY CO LTD
Endoglin nucleic acid aptamer based on CRISPR/Cas9 and application
InactiveCN109576274AAvoids differences in native conformationAccurate targetBiological testingDNA/RNA fragmentationAptamerEndoglin
The invention discloses Endoglin nucleic acid aptamer based on CRISPR / Cas9 and application, and belongs to the technical field of genetic engineering, immunology and oncology. The Endoglin nucleic acid aptamer is any one or more sequences in nucleotide sequences shown in SEQ ID NO: 1-4. The endoglin nucleic acid aptamer is screened by a whole-cell subtraction Cell-SELEX technology, the molecular weight is small, the endoglin nucleic acid aptamer is easy to synthetize and modify, can recognize Endoglin in a high-specificity mode and can be bonded with Endoglin in a high-affinity mode, does notconduct feature bonding with other cells, is free of immunogenicity, is stable and easy to modify, and is convenient to synthetize and store. An Endoglin detection kit and reagent paper prepared by the Endoglin nucleic acid aptamer have high detection sensitivity to Endoglin, and are prone to optimization. The Endoglin nucleic acid aptamer is applied to assessment of tumor diagnosis and tumor prognosis and monitoring, and tumor diagnosis.
Owner:GUANGXI MEDICAL UNIVERSITY
Rapid detection of lean meat powder in pork
The invention discloses a gold-magnetic immunochromatographic test strip for rapid quantitative detection of lean meat powder (clenbuterol hydrochloride and ractopamine) in pork. The test strip comprises a base plate, a sample pad, a conjugate release pad, a porous filter membrane and an absorption pad, wherein the sample pad, the conjugate release pad, the porous filter membrane and the absorption pad adhere to the base plate and are connected in sequence. The porous filter membrane is coated with a detection line T1 for a clenbuterol hydrochloride-BSA coupled antigen, a detection line T2 for a ractopamine-BSA coupled antigen and a quality control line C coated with a goat-anti-mouse secondary antibody in sequence, and a monoclonal antibody, marked with gold-magnetic nanoparticles, for clenbuterol hydrochloride and ractopamine is embedded in the sample pad. The test strip combines the advantages of color development and bio-affinity of a colloidal gold test strip, and the advantages of nano-magnetic beads that separation is easy and quantitative detection can be achieved; by means of the prepared test strip, qualitative detection can be conducted through visual inspection, and quantitative detection can also be conducted through magnetic measurement.
Owner:陈军 +1
Carbon dot fluorescent probe, and preparation method and application thereof
PendingCN110982514AHigh selectivityImprove specific recognitionFluorescence/phosphorescenceLuminescent compositionsFluoProbesHybrid material
The invention discloses a preparation method of a carbon dot fluorescent probe. The method comprises the following steps: stirring and dispersing an umbelliferone derivative and amino acids in an aqueous solution, performing a reaction at 180-200 DEG C for 12-15 h, centrifuging the obtained suspension to remove large particles, filtering the obtained supernatant by a 0.22-0.25 [mu]m filter membrane to thoroughly remove the large particles, and dialyzing and freeze-drying the filtered supernatant to obtain the product. The probe can realize high-sensitivity and high-selectivity detection of Fe<3+>. The synthesis strategy of the carbon dot hybrid material is provided, a new way is opened up for ion detection, and high-selectivity and specific recognition of iron ions in a water phase is realized.
Owner:THE SECOND RES INST OF CIVIL AVIATION ADMINISTRATION OF CHINA
Bifunctional probe for identifying iron ions and fluoride ions, preparation and application of bifunctional probe
ActiveCN109900670AThe synthesis steps are simpleHigh synthetic yieldMaterial analysis by observing effect on chemical indicatorColor/spectral properties measurementsSynthesis methodsPhysical chemistry
The invention discloses a bifunctional probe for identifying iron ions and fluoride ions, a preparation and application of the bifunctional probe. The bifunctional probe is of a structure representedby a formula I described in the descriptions of the invention. The synthesis method of the bifunctional probe of the invention is simple and enables a high yield. The bifunctional probe can realize the detection of iron ions and fluoride ions and is reversible in the identification of the fluoride ions.
Owner:UNIV OF JINAN
Set of HDACs nucleic acid aptamers
InactiveCN109609506ASmall molecular weightEasy to synthesize and modifyBiological material analysisDNA/RNA fragmentationGenetic engineeringWilms' tumor
The invention discloses a set of HDACs nucleic acid aptamers, and belongs to the technical field of genetic engineering, immunology and oncology. The aptamers are any one or several nucleotide sequences as shown in SEQ ID NO: 1-5. The nucleic acid aptamers of the invention are obtained by screening with a protein SELEX technology, have a small molecular weight, are easy to synthesize and modify, and can recognize HDACs with high specificity and bind with the HDACs with high affinity. The aptamers do not bind with other protein, have no immunogenicity, are stable and easy to modify, and are easy to synthesize and preserve. An HDACs detection kit and reagent papers prepared from the aptamers can detect the HDACs with high sensitivity, and are easy to optimize. The aptamers are used in tumordiagnosis, evaluation of tumor prognosis and monitoring, and tumor diagnosis.
Owner:GUANGXI MEDICAL UNIVERSITY
Synthetic method for metolcarb artificial antigen
InactiveCN1616481AEfficient manufacturingImprove specific recognitionPeptide preparation methodsDepsipeptidesChemical reactionPropanoic acid
The present invention relates to synthetic technology of artificial metolcarb antigen, and belongs to the field of organic chemistry and immunological technology. The organic chemical process of synthesizing metolcarb semi-antigen and antigen includes: synthesis of m-methyl benzoyl chloride, synthesis of beta-(m-methyl benzoyl) amino propanoic acid, synthesis of artificial metolcarb antigen, and packing the white artificial metolcarb antigen emulsion in 1 ml centrifugal tubes and preserving at -20 deg.c in refrigerator. The antigen has the features of high stability, powerful immunogenicity, etc. and may be used in preparing metolcarb antigen with high potency and high compatibility. The present invention has simple preparation process.
Owner:NANJING AGRICULTURAL UNIVERSITY
Fluorescent molecularly imprinted polymer based on glycopeptide, preparation method and application in glycoprotein screening and detection
ActiveCN113189064AImprove specific recognition abilityStrong specificityFluorescence/phosphorescenceLuminescent compositionsGlycopeptideMolecularly imprinted polymer
The invention discloses a fluorescent molecularly imprinted polymer based on glycopeptide, a preparation method and application in glycoprotein screening and detection. The fluorescent molecularly imprinted polymer is prepared by the following steps of dispersing short glycopeptide immobilized N-GQDs@SiO2@FPBA of OVA in a phosphate buffer solution, adding MAA and MBA, performing ultrasonic dissolution, pre-assembling at 28-32 DEG C for 11-13 hours, then adding TEMED and APS, reacting at 28-32 DEG C for 5-7 hours under the protection of inert gas, eluting, and acquiring the fluorescent molecularly imprinted polymer based on the glycopeptide. Compared with a traditional glycoprotein detection method, the fluorescent molecularly imprinted polymer based on glycopeptide has the advantages of high specific recognition and sensitive and rapid detection, and screening and detection of trace target glycoprotein from a biological sample are very significant.
Owner:XI AN JIAOTONG UNIV
Application of dual-photon fluorescence probe
ActiveCN109946276AAvoid interferenceImprove accuracyOrganic chemistryFluorescence/phosphorescenceImage resolutionFluorescence
The invention relates to the technical field of the dual-photon fluorescence probe, and specifically relates to an application of the dual-photon fluorescence probe. The dual-photon fluorescence probeis applied to the cell and tissue imaging and used for detecting lipid raft content and distribution dynamic; the probe can improve the accuracy, precision, sensitivity and imaging resolution of thelipid raft detection, thereby providing a new thought for further preventing and controlling Alzheimer's disease and Prion Disease and like neurodegenerative diseases.
Owner:ZUNYI NORMAL COLLEGE
X-ray multicolor genetic marker probe based on synchronous light source as well as preparation method and application thereof
ActiveCN110819656AAchieve positioningImprove specific recognitionMaterial analysis using wave/particle radiationPreparing sample for investigationProtein targetHigh resolution imaging
The invention provides an X-ray multicolor genetic marker probe based on a synchronous light source as well as a preparation method and an application thereof. The preparation method comprises the following steps: 1) constructing at least two fusion expression plasmids simultaneously comprising enzymes and target proteins, and simultaneously transfecting the fusion expression plasmids into cells;2) fixing the cells in an ice bath by using glutaraldehyde fixing liquid; 3) adding a first DAB-metal complex, and carrying out an ice bath reaction; 4) removing the reaction liquid, and adding a confining liquid; 5) adding a second DAB-metal complex, and carrying out the ice bath reaction; 6) if three or more than three fusion expression plasmids are constructed, repeating the steps 4) and 5); 7)removing the reaction liquid and fixing the cells; and (8) performing synchronous X-ray imaging observation, wherein each DAB-metal polymer has a specific fluorescence peak under X-rays, and obtaining the X-ray multicolor genetic marker probe. According to the invention, a method capable of carrying out high-specificity recognition and high-resolution imaging on various biomolecules in cells atthe same time is provided, and the method has a good biomedical application prospect.
Owner:SHANGHAI ADVANCED RES INST CHINESE ACADEMY OF SCI
Dual-targeting compound, its preparation method and application
ActiveCN110075299BImprove specific recognitionImaging results are clearly identifiableOrganic chemistryPhotodynamic therapyParanasal Sinus CarcinomaOncology
The invention provides a compound, which is obtained by splicing a heptamethine cyanine structure and an epidermal growth factor receptor(EGFR) targeted drug molecular structure. The compound providedby the invention can be used as a hypoxia and EGFR double-targeted near infrared fluorescence probe, can realize the purpose of accurate imaging on malignant tumor lesions with high EGFR expression by targeting the tumor marker EGFR and the hypoxia state of tumor cells; in addition, the compound provided by the invention can be used as a photosensitizer for cancer treatment.
Owner:NINGBO HAIBO BIOTECHNOLOGY CO LTD
A colorimetric probe for identifying iron ions and its preparation and application
ActiveCN109932363BGood optical performanceThe synthesis steps are simpleMaterial analysis by observing effect on chemical indicatorColor/spectral properties measurementsPhysical chemistryAnalytical chemistry
The invention discloses a colorimetric probe for identifying iron ions and its preparation and application. The colorimetric probe has a structure shown in formula I: the colorimetric probe of the invention is prepared by one-step synthesis, and the synthesis conditions The method is simple, easy to purify and high in yield; the prepared colorimetric probe has a strong ability to identify iron ions and a fast response speed, and has practical application value in the fields of biochemistry, environmental science and the like.
Owner:UNIV OF JINAN
A preparation method of organic-inorganic hybrid porous material for separating propylene propane
ActiveCN112439388BEasy to makeLow equipment requirementsOther chemical processesAdsorption purification/separationPyrazinePhysical chemistry
The invention relates to the technical field of chemical separation, and discloses a method for preparing an organic-inorganic hybrid porous material for separating propylene propane. The organic-inorganic hybrid porous material of the present invention is based on the inorganic metal ion Ni 2+ , Inorganic anion SiF 6 2‑ The microporous metal-organic framework material obtained under solvothermal conditions with the organic ligand 2-mercaptopyrazine has a relatively large specific surface area, and exhibits more suitable channels with shrinking pore sizes, which is more conducive to the capture of C 3 h 6 molecule, while restricting C to some extent 3 h 8 The capture in the channel has the characteristics of fast and efficient, high adsorption capacity, high selectivity and reuse after desorption. In addition, the present invention combines bifunctional groups ("-SH and SiF 6 2‑ ”) into the framework structure of hybrid porous materials, which can generate multiple binding environments to improve C 3 h 6 specific identification.
Owner:杭州市富阳区浙工大银湖创新创业研究院 +2
Preparation method of bisphenol A-coated antigen with polylysine as carrier and application thereof
The present invention discloses a preparation method of bisphenol A-coated antigen with polylysine as a carrier and application thereof, is aimed at providing the preparation method of bisphenol A-coated antigen with polylysine as the carrier which is simple in the synthetic method and the application thereof, and finally establishes an enzyme linked immunosorbent assay kit. The kit has the advantages of simple pre-treatment, fast speed and accuracy and low cost, and can be used for on-site testing in large scale. The technical points include: taking polylysine as a carrier protein, preparing bisphenol A-coated antigen by coupling with diphenolic acid, and applying the bisphenol A-coated antigen to prepare the bisphenol A enzyme linked immunosorbent assay kit, wherein the bisphenol A enzyme linked immunosorbent assay kit is composed of a solid phase carrier of envelope antigen, an antibody working solution, a bisphenol A standard solution, an enzyme labeled secondary antibody solution, an antibody diluent, a wash concentrated solution, a substrate solution and a stop solution. The preparation method belongs to the technical field of enzyme linked immunoassay.
Owner:深圳市绿诗源生物技术有限公司
A colorimetric sensor, detection system and application for the detection of mycotoxins in food
ActiveCN113219163BRapid Colorimetric DetectionAvoid binding effectsColor/spectral properties measurementsBiological testingMycotoxinToxin detection
The invention relates to the technical field of food toxin detection, in particular to a colorimetric sensor, detection system and application for the detection of mycotoxins in food. The colorimetric sensor includes an aptamer sequence, and also includes nanomaterials that modify HS-DNA, and the HS-DNA sequence is a sequence that is complementary to the aptamer sequence and has mismatched bases in the middle. The colorimetric sensor has the advantages of enzyme-free, low cost, simple preparation, rapid on-site visualization, and high sensitivity, and can realize on-site rapid and visual detection of mycotoxins in liquid food.
Owner:OCEAN UNIV OF CHINA
A kind of functional detection paper and its preparation method and application
ActiveCN110702671BRealize visual detectionImprove specific recognitionMaterial analysis by observing effect on chemical indicatorPolymer scienceCarboxylic acid
The invention discloses a functional detection paper and its preparation method and application. The structure of the functional detection paper contains high-density amino groups, carboxyl groups, and sulfur-containing groups, and through the synergistic effect of the three groups, the detection of Ag + 、Cu 2+ rapid and high-sensitivity detection; the functional detection paper is based on polyacrylonitrile fiber, which is aminated with amine reagents to obtain aminated polyacrylonitrile fiber, and then combined with two kinds of sulfur-containing polyacrylonitrile fibers of type A and type B Carboxylic acid small-molecule reagents are subjected to amidation reaction to prepare polyacrylonitrile-based functional fibers, and finally polyacrylonitrile-based functional fibers are mixed with bleached pulp fibers and reinforcing agents to form paper, and functional detection paper is prepared. The function detection paper of the present invention is simple and portable, has stable performance and low cost, and can realize the detection of Ag + 、Cu 2+ Rapid and highly sensitive detection of Ag + 、Cu 2+ The detection sensitivity can reach 10 ‑7 mol / L, the detection response time is 10-120s.
Owner:GUANGXI UNIV
Dengue fever ns1 antigen, IgG/IGM antibody dual detection test strips, detection cards and kits
ActiveCN112362870BShow immune response statusEasy to operateBiological testingImmunoassaysNitrocelluloseIgm antibody
Owner:山东康华生物医疗科技股份有限公司
A bifunctional probe for recognizing iron ions and fluorine ions and its preparation and application
ActiveCN109900670BThe synthesis steps are simpleHigh synthetic yieldMaterial analysis by observing effect on chemical indicatorColor/spectral properties measurementsFluoridePhotochemistry
Owner:UNIV OF JINAN
Stilbene Estrogen Nucleic Aptamer and Its Application
ActiveCN111705062BReduce harmImprove specific recognitionBiological testingDNA/RNA fragmentationAptamerOrganic chemistry
Owner:HUAQIAO UNIVERSITY
Photo-fuel cell sensor based on anode light induction and pollutant analysis method
ActiveCN111337563AHigh selectivityEasy to operateMaterial electrochemical variablesPower sensorFuel cells
The invention relates to a photo-fuel cell self-powered sensor based on anode light induction and an environmental pollutant analysis method. The sensor comprises a photo-anode, a cathode, photo-anodefuel and cathode fuel; the photo-anode is a Ti-Fe-O NTs / Ni (OH) 2 electrode, the cathode is a GSE / G / MIP electrode, the photo-anode fuel is glucose, and the cathode fuel is K3 [Fe (CN) 6]. Compared with the prior art, a detection mode of energy supply and sensing separation is realized; the output power, the stability and the selectivity of the self-powered sensor are greatly improved, the sensitivity is high, and the detection limit on environmental pollutants ATZ and the like is as low as 2.81 pM. Meanwhile, the preparation method is simple, the cost is low, the analysis method is simple andconvenient, and the method has good reproducibility and an application prospect for on-site determination.
Owner:TONGJI UNIV
A kind of purposes of two-photon fluorescent probe
ActiveCN109946276BMolecular response time is shortHigh detection sensitivityOrganic chemistryFluorescence/phosphorescenceImage resolutionFluorescence
The present invention relates to the technical field of two-photon fluorescent probes, in particular, to the use of a two-photon fluorescent probe, which is used in cell and tissue imaging to detect lipid raft content and distribution dynamics. The probe can improve the accuracy, precision, sensitivity, and imaging resolution of lipid raft detection, and provide new ideas for further prevention and control of neurodegenerative diseases such as Alzheimer's disease and prion disease.
Owner:ZUNYI NORMAL COLLEGE
A method for detecting Salmonella
ActiveCN107084962BImprove specific recognitionAchieve high specificity detectionFluorescence/phosphorescenceAptamerFluorescence
Owner:UNIV OF JINAN
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