48results about How to "Restore liver function" patented technology

The present invention relates to a novel tissue culture system that provides for the long term culture of proliferating hepatocytes that retain hepatic function. Disclosed are methods and compositions for ex vivo culturing of hepatocytes and nonparenchymal cells on a matrix coated with a molecule that promotes cell adhesion, proliferation or survival, in the presence of growth factors, resulting in a long-term culture of proliferating hepatocytes that retain hepatic function. The co-culturing method results in the formation of matrix/hepatic cell clusters that may be mixed with a second structured or scaffold matrix that provides a three-dimensional structural support to form structures analogous to liver tissue counterparts. The hepatic cell culture system can be used to form bio-artificial livers through which a subjects blood is perfused. Alternatively, the novel hepatic cell culture system may be implanted into the body of a recipient host having a hepatic disorder. Such hepatic disorders, include, for example, cirrhosis of the liver, induced hepatitis, chronic hepatitis, primary sclerosing cholangitis and alpha1 antitrypsin deficiency.

A method is provided for long term culture of proliferating hepatocytes that retain hepatic function to produce a hepatic cell culture. Hepatocytes and nonparenchymal cells are co-cultured ex vivo on a matrix coated with a molecule that promotes cell adhesion, proliferation or survival, in the presence of growth factors, resulting in a long-term culture of proliferating hepatocytes that retain hepatic function. The co-culturing method results in the formation of matrix/hepatic cell clusters that may be mixed with a second structured or scaffold matrix that provides a three-dimensional structural support to form structures analogous to liver tissue counterparts. The method can be used to form bio-articial livers through which a subjects blood is perfused. In an embodiment, the hepatocytes and nonparenchymal cells are derived from disaggregated liver tissue and are co-cultured in the presence of epidermal growth factor or heptocyte growth factor and beads coated with extracellular matrix protein, Alternatively, the hepatic cell culture may be implanted into the body of a recipient host having a hepatic disorder. Such hepatic disorders, include, for example, cirrhosis of the liver, induced hepatitis, chronic hepatitis, primary sclerosing cholangitis and alpha1 antitrypsin deficiency.

The invention discloses application of a chlorogenic acid in preparation of medicines for treating pathologic jaundice, and belongs to the field of biological medicines. The medicines prepared from the chlorogenic acid as an active component are capable of powerfully promoting biosynthesis of glutathione, so as to effectively play a role in stabilizing a red cell membrane and inhibit release of bilirubin (indirect bilirubin), and simultaneously are capable of recovering the injured liver function and effectively reducing the activity of alpha-glutathione-s-transferase (alpha-GST), alanine aminotransferase (ALT) and aspartic transaminase, so as to promote transformation of the indirect bilirubin into direct bilirubin and drainage through the liver and biliary tracts. Therefore, the content of total bilirubin and indirect bilirubin in the blood is effectively reduced; and new means and choice are provided for drug treatment of pathologic jaundice, especially hemolytic jaundice.

The present invention discloses a composition preparation for preventing and treating diabetes, which mainly contains oral hypoglycemic agents, Vitamin E, chromic pyridine formate, selenium, lutein, folic acid, Vitamin C, alpha_lipoic acid, lycopene, nicotinamide, coenzyme Q10, and vitamin complexes and mineral. The medicament of the invention can decrease oxidative stress in vivo, promote body immunity, repair the critical organs in vivo such as pancreas, by supplying the mineral, vitamins and other substances which are insufficient in the patient suffering from diabetes, to prevent and treat diabetes.

The invention relates to the technical field of drinks and particularly relates to a health-care tea. The health-care tea comprises the following raw materials: 4g of penthorum chinense pursh, 1.5g of tuckahoe, 1.5g of radix bupleuri, 1.5g of salvia miltiorrhiza, 2.5g of medlar, 1.3g of Chinese-date, 1.5g of herba lysimachiae, 1.2g of shizandra berry and 1g of semen cassiae. The raw materials are firstly crushed into powder; then, the power is stirred and mixed evenly; and finally the power is packaged with small bags; and powdery raw materials are obtained by pressing and grinding the raw materials dried in the sun. Compared with the prior art, the health-care tea is prepared from penthorum chinense pursh, tuckahoe, radix bupleuri, salvia miltiorrhiza, medlar, Chinese-date, herba lysimachiae, shizandra berry, semen cassia and the like, has the functions of protecting the liver, effectively improving human immunity and strengthening the body, and has no toxic or side effects.

The present invention provides a female brown sugar nourishing composition, which is characterized by comprising the following components, by weight, 78-80 parts of brown granulated sugar, 6-9 parts of ginger powder, 6-8 parts of red date, and 7-8 parts of lobed kudzuvine root. The female brown sugar nourishing composition of the present invention has the following advantages that: female menstrual period regulation can be improved; dysmenorrhea can be released; a good regulation nourishing effect is provided for menstruating women with weak body constitution, especially for young girls; and the female can regularly take the female brown sugar nourishing composition of the present invention when the female is at a menstrual period so as to release abdominal pain, enrich blood, regulate human body immune system, and improve immunity.

The invention discloses an alcohol-effect-dispelling and health-maintaining plant beverage and a preparation method of the alcohol-effect-dispelling and health-maintaining plant beverage. The invention provides a plant beverage which has the alcohol-effect-dispelling and sobering-up effects and also has the health-maintaining and health functions, and a preparation method of the plant beverage. The beverage is composed of following raw materials in parts by weight: 1-10 parts of gynostemma pentaphylla, 1-7 parts of glycyrrhiza uralensis, 10-25 parts of hovenia dulcis thumb, 15-45 parts of lobed kudzuvine roots, 10-35 parts of lobed kudzuvine flowers and 1-10 parts of crataegus pinnatifida bunge. The alcohol-effect-dispelling and health-maintaining plant beverage further comprises a flavoring agent composed of white granulated sugar, citric acid, potassium sorbate and fruity essence. All the raw materials are reasonably matched and have a synergistic effect; the intestines and stomach absorption of alcohol is inhibited by effects of sweating, promoting diuresis, relaxing the bowels and the like, the first pass effect of the alcohol in gastrointestinal tracts is enhanced and the concentration of the ethanol in blood is reduced; meanwhile, medicines directly act on a liver metabolic enzyme system so as to enhance the activity of ethanol dehydrogenase, accelerate the elimination speed of the ethanol and metabolites thereof, and relieve the injuries to tissues and cells; the alcohol-effect-dispelling effect is very obvious and the sleeping time is shortened; the sobering-up recovery time is 62.3 minutes.

The invention discloses a nutritional health care product for treating chronic hepatitis B, which belongs to the technical field of nutritional food. The nutritional health care product for treating the chronic hepatitis B is a medicine prepared from the following bulk drugs in proportion: yam, chrysanthemum, mulberry, sword bean, Chinese wolfberry, radix rehmanniae, radix pseudostellariae, liquorice, date, bupleurum, radix paeoniae alba, astraolylis lancea formalyrata, tuckahoe, green tangerine orange peel, herba artenisiae capillaris, radix curcumae, oldenlandia diffusa, gerba scutellariae barbatae, radix cynanchi paniculati, loosestrife, and dyer woad leaf. The nutritional health care product uses the bupleurum, the radix paeoniae alba, the astraolylis lancea formalyrata, the tuckahoe and the liquorice to soothe liver and relieve stagnation so as to regulate the liver, uses the drugs of the herba artenisiae capillaris, the oldenlandia diffusa, the radix cynanchi paniculati, and the like to clear away heat and toxic material and remove dampness and free collateral vessels, uses the green tangerine orange peel and the radix curcumae to soothe the liver and regulate qi, and uses the drugs of yam, the chrysanthemum, the mulberry, the sword bean, the Chinese wolfberry, the radix rehmanniae, the radix pseudostellariae, and the like to tonify and replenish the liver and kidney, and fortify spleen and stomach. The traditional Chinese medicine composition can block and eliminate the hepatitis B virus so that the virus signature turns to negative, and enhance the immunity of organisms and restore the liver function simultaneously.

The invention relates to agonistic anti-MET antibodies and uses thereof in the therapeutic treatment of disease. The antibodies bind with high affinity to the human and mouse hepatocyte growth factor (HGF) receptor, also known as MET, and are agonists of MET in both humans and mice, producing molecular and cellular effects resembling the effects of HGF binding.

The invention discloses a preparation method of a fat reducing and weight losing dandelion oral solution. The step c of the method includes: combining a component 1 and a component 2, then putting the mixture into a double-effect vacuum concentrator, and performing concentration to obtain a concentrated liquid with a 90DEG C relative density of 1.36, then conducting low temperature preservation at 0-5DEG C; adding 0.3% of a filter aid diatomite into the refrigerated liquid, performing filtering, then putting the filtrate into the double-effect vacuum concentrator, conducting concentration to a state that 1ml of the liquid contains 0.1g of crude drug; adding honey or dextrin into the concentrated paste and performing blending, carrying out ultraviolet sterilization and then performing bottling. Experiments prove that the oral solution provided by the invention can promote fat metabolism and decomposition and maintain normal physiological functions, overcomes the disadvantages that food substituting type, excretion type, nerve suppression type and other weight-losing products damage dietary law, lower human body functions and induce other diseases, and is a very good fat reducing and weight losing product.

The invention discloses a maca compound traditional Chinese herb preparation. The maca compound traditional Chinese herb preparation is composed, by weight, of 50-60 parts of maca powder, 10-20 parts of pueraria, 20-30 parts of gastrodia elata, 45-55 parts of turmeric powder, 20-30 parts of semen cassiae and 5-15 parts of ginkgo biloba. The invention further discloses a preparation method of the maca compound traditional Chinese herba preparation. Maca, semen cassiae and other herbs are extracted respectively in a preparation process and different extraction methods are used according to different herb properties, so that active ingredients can be fully extracted. According to the maca compound traditional Chinese herb preparation prepared through the preparation method, various ingredients are complementary for one another, a synergistic effect is obtained, and a significant effect on blood pressure and lipid reducing can be obtained.

The invention relates to a traditional Chinese preparation for treating liver lesion which comprises the constituents of (by weight percent) haw 10-20g, germinated barley 10-20g, radix adenophorae 10-20g, white peony root 10-30g, licorice root 10-30g, radix salvia miltiorrhiza 10-30g, curcuma aromatica 10-30g.

The invention discloses multifunctional selenium-rich nutritious food. The multifunctional selenium-rich nutritious food contains the following components in parts by weight: 1-35 parts of radix puerariae, 0.5-33 parts of gynura procumbens, 1-26 parts of maca, 0.5-40 parts of quinoa, 1-30 parts of buckwheat, 1-35 parts of corns, 1-45 parts of black sesame, 1-40 parts of walnuts and 1-5 parts of afood additive. The multifunctional selenium-rich nutritious food is prepared by the steps of respectively grinding raw materials into raw material particles with different particle sizes, carrying outmixing and curing by virtue of a speed reducer, and carrying out cooling. The finished product of the invention is the selenium-rich nutritious food which is convenient to brew, and the selenium-richnutritious food can be immediately drunk after brewing, is convenient, rich in nutrition, low in calorie and fat, medicinal and edible and is an optimal nutrient choice for patients with cardiovascular and cerebrovascular diseases and diabetes mellitus, crowds with ''four-highs and one-exceeding'' (hyperlipidemia, hypertension, hyperglycemia, hyperuricaemia and overweight), sub-health crowds, mental workers and people with high social engagement frequency.

A Chinese medicine in the form of particle, tablet, capsule or pill for treating chronic hepatitis is prepared from 5 Chinese-medicinal materials including bitter orange, white peony root, red sage root, astragalus root, etc. Its preparing process is also disclosed.

Methods and kits for mitigating liver injury and promoting liver regeneration and engraftment in a subject treated with a targeted radiation therapy are described. In particular, an effective amount of a thrombopoietin mimetic, such as RWJ-800088 or romiplostim, is used to mitigate the radiation-induced liver diseases and promote beneficial effects for liver regeneration and engraftment in conjunction with radiation or radiomimetics.

The invention discloses a medicine bag used for treating viral hepatitis. The medicine bag used for treating viral hepatitis comprises a non-woven medicine bag and traditional Chinese medicine powder,wherein the non-woven medicine bag is filled with the traditional Chinese medicine powder; the traditional Chinese medicine powder is prepared from the following raw materials in parts by weight: 15-30 parts of herba artemisiae scopariae, 10-15 parts of goldthread root, 15-30 parts of herba taraxaci, 15-30 parts of herba patriniae, 10-20 parts of buckwheat seed, 15-30 parts of silybi fructus, 3-6parts of gentian root, 10-15 parts of hovenia seed, 10-20 parts of safflower, 3-6 parts of curcumae longae rhizoma, 10-15 parts of fraxinus rhynchophylla seed, 3-6 parts of rhizoma valerianae jatamansi, 3-6 parts of emilia sonchifolia herb, 3-6 parts of pittosporm root and 6-8 parts of raw liquorice root. According to the medicine bag used for treating viral hepatitis, by optimizing a formula, atemporary solution and permanent cure are combined, the medicine bag used for treating viral hepatitis has the efficacy of soothing liver and strengthening spleen, clearing heat and promoting diuresis, nourishing liver and kidney, and promoting qi to activate blood, and the effects of short-term symptom relieving and long-term liver function recovery are achieved.

The invention discloses health-care tea capable of preventing and treating stroke, and relates to the technical field of health-care products. The health-care tea capable of preventing and treating stroke consists of the following raw materials in parts by weight of 65-80 parts by weight of Guangxi sweet tea, 4-6 parts by weight of American ginseng, 7-9 parts by weight of radix astragali, 16-18 parts by weight of radix salviae miltiorrhizae, 16-18 parts by weight of pseudo-ginseng, 16-18 parts by weight of radix puerariae and 7-9 parts by weight of haws. The health-care tea disclosed by the invention is prepared from traditional Chinese medicines and the Guangxi sweet tea, and the sweet tea is a natural non-toxic high-sugariness low-calorie sweet plant having good health-care functions inthe world at present, is a saccharide substitute which is widely searched by developed countries in the world, is sweet in taste and also has tea fragrance, so that the health-care tea disclosed by the invention is excellent in mouth feel, safe and free from side effects, and can replace Western medicines to prevent and treat the stroke.

An object of the present invention is to provide a means for improving hepatic function of mammals including humans to normal condition. The present invention achieves the above object by providing a hepatic function-improving agent comprising α-glucosyl-hesperidin as an effective ingredient.

The invention relates to an anglerfish feed for preventing the liver and gallbladder syndrome and a preparation method of the anglerfish feed. The feed comprises the following raw materials in parts by weight: 9 to 12 parts of corn flour, 26 to 40 parts of white fish meal, 4 to 6 parts of spray-dried animal blood cells, 2 to 4 parts of shrimp shell meal, 1.5 to 3 parts of fish oil, 12 to 18 parts of bean pulp, 8 to 14 parts of meat and bone meal, 0.5 to 2.5 parts of malt flour, 2 to 5 parts of jujube powder, 10 to 16 parts of taro powder, 2 to 6 parts of hawthorn powder, 6 to 16 parts of gentian, 6 to 15 parts of uncaria rhynchophylla, 5 to 15 parts of astragalus membranaceus, 4 to 15 parts of Chinese angelica, 6 to 16 parts of capillary artemisia and 3 to 7 parts of liquorice. The feed disclosed by the invention contains the gentian, the uncaria rhynchophylla, the astragalus membranaceus, the Chinese angelica, the capillary artemisia and other traditional Chinese medicinal compositions which are reasonably matched; the anglerfish feed can realize the effects of detoxifying, preventing liver injury, removing blood stasis and hemostasis, promoting regeneration of liver cells and recovery of liver functions, effectively reducing stress reaction and the like, so that the liver and gallbladder syndrome can be better prevented.

The invention relates to a medicament for continuing to cure tuberculosis after failure of centrum tubercle operation. The medicament is made up from hairy antler 1-9 portions, astragalus root 30-90 portions, angelica 10-14 portions, cinnamon 15-45 portions, root of herbaceous peony 8-10 portions, buttercup root 2.12-3.18 portions, Chineseephedra 4-20 portions, lilyturf root 1-5 portions, isoniazide 0.3-0.5 portions, baked ginger 15-45 portions, gen-seng 15-45 portions, Vaseline 1-2 portions, liquorice 5-7 portions, rhizome of Sichuan lovage 10-14 portions. It has good effect and low cost.