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3 results about "Feeder Layer Cells" patented technology

Feeder layer. In order to culture some cells, particularly at low or clonal density, it is necessary to use a layer of less fastidious cells to condition the medium. Often the cells of the feeder layer are irradiated or otherwise treated so that they will not proliferate.

Modified feeder cells expressing flt3l and uses thereof

This invention relates to a modified feeder cell and a method for culturing natural killer (NK) cells, aiming to enhance the proliferation capacity and killing activity of NK cells by using a specific feeder cell.
Owner:SHANGHAI IMMUNOHEAD BIOTECHNOLOGY CO LTD

Modified feeder cell and use thereof

Provided are an HLA-E modified feeder cell and a method for culturing natural killer cells (NK cells). By means of culturing NK cells using the HLA-E-modified feeder cell, NK cells having a low expression of inhibitory receptor NKG2A and a high expression of activating receptors, such as NKG2C and NKp44, can be obtained, thereby significantly enhancing the killing activity of NK cells against target cells, particularly those with a high HLA-E expression.
Owner:SHENZHEN IMMUNOFOCO BIOTECHNOLOGY CO LTD