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6 results about "Haematoxylin" patented technology

Haematoxylin or hematoxylin (/ˌhiːməˈtɒksɪlɪn/), also called natural black 1 or C.I. 75290, is a compound extracted from heartwood of the logwood tree (Haematoxylum campechianum) with a chemical formula of C₁₆H₁₄O₆. This naturally derived dye has been used as a histologic stain, ink and as a dye in the textile and leather industry. As a dye, haematoxylin has been called Palo de Campeche, logwood extract, bluewood and blackwood. In histology, haematoxylin staining is commonly followed (counterstained), with eosin, when paired, this staining procedure is known as H&E staining, and is one of the most commonly used combinations in histology. In addition to its use in the H&E stain, haematoxylin is also a component of the Papanicolaou stain (or PAP stain) which is widely used in the study of cytology specimens.

Method for dyeing suture material

PCT designated stageWO2026112344A2Suture equipmentsFibre typesActive agentSurgery
Methods for dyeing suture material that include incubating the suture material in a high temperature staining bath comprising hematein are disclosed. The staining bath may include a nonionic surfactant. The method is carried out in the absence of chromium salts. Also disclosed are (i) a dyed suture material produced by the methods and (ii) a surgical suturing kit that includes the dyed suture material.
Owner:CORZA MEDICAL INC

Training method of pathological image recognition model, pathological image recognition method and device

The application relates to the technical field of medical data processing, and discloses a training method of a pathological image recognition model, a pathological image recognition method and device, the training method of the pathological image recognition model comprising the following steps: obtaining a plurality of histopathological image samples; for part or all of the histopathological image samples, converting a color space into an H&E space to obtain an initial H&E space image, the H&E space comprising two color channels, namely a hematoxylin color channel and an eosin color channel; for the initial H&E space image, using a B-spline curve function to perform dyeing enhancement processing or dyeing weakening processing on at least one color channel to obtain a target H&E space image; and using the histopathological image samples and the target H&E space image to train a pre-constructed histopathological image recognition model. The application can improve the generalization ability of the histopathological image recognition model, and further improve the accuracy.
Owner:HYBRIBIO MEDTECH DEVICE CO LTD +1

Method for dyeing suture material

Methods for dyeing suture material that include incubating the suture material in a high temperature staining bath comprising hematein are disclosed. The staining bath may include a nonionic surfactant. The method is carried out in the absence of chromium salts. Also disclosed are (i) a dyed suture material produced by the methods and (ii) a surgical suturing kit that includes the dyed suture material.
Owner:CORZA MEDICAL INC

Method for dyeing suture material

PCT designated stageWO2026112344A3Dyeing processActive agentSurgery
Methods for dyeing suture material that include incubating the suture material in a high temperature staining bath comprising hematein are disclosed. The staining bath may include a nonionic surfactant. The method is carried out in the absence of chromium salts. Also disclosed are (i) a dyed suture material produced by the methods and (ii) a surgical suturing kit that includes the dyed suture material.
Owner:CORZA MEDICAL INC

A method for detecting spatial proteomics and spatial phosphorylation modification proteomics

This invention provides a method for detecting spatial proteomics and spatial phosphorylation modification omics. The method includes the following steps: (1) obtaining two consecutive sections of the target tissue and staining the sections with hematoxylin-eosin to obtain stained sections; (2) using a 3D printing mold to cut the stained sections into continuous, gapless strip-shaped subunits; (3) extracting peptides from the strip-shaped subunits and enriching the peptides by phosphorylation modification; (4) performing chromatographic separation and mass spectrometry detection on the phosphorylation-enriched peptides to obtain one-dimensional omics information of each strip-shaped subunit; (5) using the image of the stained sections as a spatial reference, reconstructing the one-dimensional omics information into a two-dimensional spatial distribution to obtain the spatial distribution of the target omics biomolecules. The method of this invention only requires two tissue sections to simultaneously obtain two-dimensional spatial proteomics and spatial modification omics results, which is friendly to small clinical samples.
Owner:JINGJIE PTM BIOLAB HANGZHOU CO LTD

A staining instrument for hematoxylin and eosin solution concentration determination and adjustment

ActiveCN224518298UEosinReoperative surgery
The utility model discloses a kind of dyeing instruments of hematoxylin and eosin solution concentration determination and adjustment, including the shell body of upper end open mouth, chain clamping structure is equipped in the top of shell body;Several liquid storage barrels are equipped with interval in shell body and the top of the liquid storage barrel is open, the bottom of the liquid storage barrel for storing hematoxylin and eosin solution and the liquid storage barrel for storing fresh water located in the right side of the liquid storage barrel are each equipped with drip device;Concentration detection structure is also equipped in shell body below drip device;It also includes concentration adjustment structure being equipped in the bottom of each liquid storage barrel, and the concentration adjustment structure, chain clamping structure, drip device, concentration detection structure are all with the controller of being equipped on the side wall of shell body electrical connection.The utility model has the advantages of being able to determine and adjust hematoxylin and eosin solution concentration to ensure dyeing quality and reduce waste, effectively improve work efficiency and pathological report accuracy to assist surgeon to formulate next operation plan in time.
Owner:ZHUJIANG HOSPITAL OF SOUTHERN MEDICAL UNIVERSITY