A method for dynamic fault simulation of a double-section type catalytic cracking reaction-regeneralion system comprises the steps that 1, a knowledge database is established, and a fault database is integrated; 2, based on DCS data and process model information of an industrial double-section type catalytic cracking device, a dynamic model of the double-section type catalytic cracking reaction-regeneralion system is established, and a dynamic model library of the double-section type catalytic cracking reaction-regeneralion system is established; 3, basic input data under different operating conditions is obtained according to the knowledge database, and steady-state working points for dynamic simulation are calculated; 4, specific fault types are selected from the fault database and converted into input deviations of the dynamic model, and dynamic fault simulation is performed; 5, an intelligent fault analysis module is applied to verify the fault types, simulation results are entered into the fault database to perfect the database. The system for dynamic fault simulation of the double-section type catalytic cracking reaction-regeneralion system comprises a DCS data acquisition module, the dynamic model of the double-section type catalytic cracking reaction-regeneralion system, the knowledge database, the knowledge database and the intelligent fault analysis module.