The invention discloses a preparation method for active dendrobium candidum superfine powder. The preparation method comprises steps: first, leaves of harvested fresh dendrobium candidum are removed, and washing and draining are carried out; second, punching is carried out, the dendrobium officinale is fixed on a die, the die is placed on a shelf of a vacuum drying container, cooling is carried out, the die is a cube-shaped metal die body (1) with an upper surface equipped with a half-cylindrical groove (2), and small holes (3) are arranged in the die body; third, vacuum-pumping is carried out; fourth, the shelf is heated, the temperature is risen to 0 DEG C, the pressure intensity is kept at 20-100Pa, drying is carried out, the material temperature is risen from 0 DEG C to 20 DEG C, the pressure intensity is kept at 10-20Pa, drying is carried out, the material temperature is risen from 20 DEG C to 40 DEG C, the pressure intensity is kept within 10Pa, drying is carried out, pressurization to a normal pressure is carried out; fifth, low temperature air-flow crushing is carried out, and active dendrobium candidum superfine powder is obtained and more than 95% of active dendrobium candidum superfine powder has a particle size of being less than 20 micrometers. The freeze-drying rate is high, freeze-drying time is saved, energy consumption is lowered, the product has a small particle size and is easy to dissolve and absorb, and the bioavailability is high.