The invention discloses a mineral processing process of low-grade micro-fine particle embedded iron ore hard to choose. The process comprises the following steps that first ore grinding and staged treatment is carried out firstly, settled sand is retuned to be ground again, second ore grinding and staged treatment is carried out on overflow, the settled sand is returned to a system to be ground again, the overflow enters a weak magnetic-strong magnetic system, low intensity magnetic separation treatment is carried out firstly, strong magnetic separation is carried out on tailings after the low intensity magnetic separation many times after concentration and residue separation, rough concentrates obtained through the strong magnetic separation are combined with rough concentrates after the low intensity magnetic separation, three-stage ore grinding and staged treatment is carried out, the settled sand is returned to be ground again, selective flocculation desliming operating is carried out on the overflow many times, the low intensity magnetic separation is carried out on the deslimed settled sand to obtain weak magnetic concentrates, weak magnetic tailings are concentrated and enter in reverse flotation operating to obtain reverse flotation concentrates, and reverse flotation foam enters the weak magnetic-strong magnetic system for direct strong magnetic separation treatment. The process has the advantages of being easy, convenient and stable to operate, high in iron ore concentrate recovery rate and grade, low in cost, small in the number of adopted agents and the like.