The invention relates to a ventilation and heat preservation module heating and cooling floor and energy-saving ventilation and air conditioning system which comprises a ventilation and heat preservation module heating and cooling floor body, a ventilation and air conditioning system body and a heat preservation and ventilation window. The ventilation and heat preservation module heating and cooling floor body is composed of an expandable polyethylene cushion layer, a ventilation and heat preservation module body, a floor heating pipeline, a water division and collection device, a dehumidification and heat radiation air supply pipe, a dehumidification and heat radiation air channel, a dehumidification and heat radiation air collection pipe, an air conditioner floor air supply pipe, a dampproof heat conduction layer and a wood floor from bottom to top in sequence. The heat preservation and ventilation window and the ventilation and air conditioning system body are communicated to form the complete energy-saving ventilation and air conditioning system. The K value of the window is improved, the heat preservation and ventilation window is adopted as an air inlet and exhaust channel, and the energy consumption of a ventilation air conditioner is lowered. The effect of the ventilation air conditioner is improved, a floor heating tail end has the two purposes for heating and cooling, waste heat is recycled, and mounting and running cost is lowered. The aims that air is purified, and a user can breathe clean and fresh air without opening the window are achieved.