The invention discloses a synthesis process of a thermosensitive color developing agent 3, 3 '-benzenesulfonyloxy diphenyl
urea, and belongs to the technical field of
organic synthesis. According to the process, m-aminophenol,
benzene sulfonyl chloride and
triphosgene are used as raw materials, 1, 2-
dichloroethane is used as a
solvent,
triethylamine is used as an acid-binding agent, a one-pot method is adopted to construct a two-step
continuous reaction through sulfonylation and
urea bonds, then acidification, liquid separation, extraction, spin-
drying and
methanol crystallization are performed to obtain a target product, and no intermediate needs to be separated in the whole process. According to the invention, parameters such as
reaction temperature and feed ratio are optimized, the problems of tedious preparation process and low yield in the prior art are solved, the reaction condition is mild, the operation is convenient, the
raw material is a conventional analytically pure
reagent, the product yield is 72-76%, the purity is greater than 99.5%, the
raw material utilization rate is high, the industrial application prospect is good, and the product can be widely used as a thermosensitive color developing agent.