The invention relates to a high-strength, lightweight, environment-friendly and porous interior wall diatomite brick with visible light photocatalysis performance and a preparation method of the interior wall diatomite brick. Diatomite, kaoline, chrysotile fibers, a macromolecule adhesive and feldspar are mixed and pressed to form a green body, the green body is dried, calcined and cooled, a diatomite brick is obtained, coated with bismuth tungstate, then calcined and cooled, and the interior wall diatomite brick is obtained. According to the interior wall diatomite brick, the excellent special performance of the diatomite serving as a main base material is utilized, the chrysotile fibers and a bismuth tungstate photocatalyst are added, the mechanical property of the interior wall diatomite brick is improved, and the photocatalysis effect under visible light is realized. Besides, a novel environment-friendly building material capable of decomposing toxic and harmful gas in a room and integrating functions of humidity conditioning, thermal insulation, antibacterium, sound absorption, heat preservation, air purification, flame retardance and the like can be further produced.