40 results about "Acaudina molpadioides" patented technology

The invention relates to an aquatic product processing method, in particular to a quick skinning method for Acaudina molpadioides Semper. The invention discloses the quick skinning method for the Acaudina molpadioides Semper. The method comprises the following steps of: setting the shape of a fresh Acaudina molpadioides Semper, mechanically grinding skin, cleaning and removing stain, skinning in an enzymolysis way, cleaning and removing stain, repeatedly carrying out enzymolysis and the like. When the skin is mechanically ground, more than a half of the silt-containing skin of the Acaudina molpadioides Semper can be removed, and the skin of the Acaudina molpadioides Semper can be completely removed within a short time by means of skinning in an enzymolysis way, so that the Acaudina molpadioides Semper body can be changed to be clean and translucent, an edible part of a wall of the inner layer body of the Acaudina molpadioides Semper can not be influenced, and the nutritional ingredients of the Acaudina molpadioides Semper can be furthest remained. The skin of an Acaudina molpadioides Semper product prepared by means of cleaning and packing is free from silt, and the heavy metal content reaches the standard, so that the Acaudina molpadioides Semper product can be used for dipping and processing or can be used as the raw material for deep processing.

The invention relates to a method for identifying acaudina molpadioides by using a specific peptide fragment group, and a group of comparison polypeptides used for identifying the acaudina molpadioides with a mass-spectrography method. A sequence of each polypeptide is SEQ ID NO.1-.5 and is not expressed in other species.

The invention provides a sea cucumber polysaccharide and sea cucumber collagen polypeptide combined preparation method. The sea cucumber polysaccharide and sea cucumber collagen polypeptide combined preparation method includes subjecting Acaudina Molpadioides serving as a raw material to mild two-stage enzymolysis treatment and obtaining Acaudina Molpadioides polypeptide mixed liquor and Acaudina Molpadioides polysaccharide mixed liquor by an ultrafiltration membrane separation technology; selecting ultrafiltration membranes different in molecular weight cut-off to achieve graded separation of Acaudina Molpadioides polypeptide and Acaudina Molpadioides polysaccharide so as to obtain Acaudina Molpadioides polypeptide products with three molecular weights and Acaudina Molpadioides polysaccharide products with four molecular weights. The sea cucumber polysaccharide and sea cucumber collagen polypeptide combined preparation method has the advantages that sea cucumber polypeptide and sea cucumber polysaccharide products different in molecular weight in Acaudina Molpadioides can be prepared in a combined manner, so that waste discharge during extraction is reduced and production cost is lowered.

The invention provides a method for preparing sea cucumber fucoidan and sea cucumber glycoprotein. According to the method, acaudina molpadioides serves as the raw material, a mild stepped enzymolysis processing method is mainly adopted, an ultrafiltration membrane is utilized to separate out a mixture of crude polysaccharide and glycoprotein, then separation, purification and preparation of the sea cucumber fucoidan and the sea cucumber glycoprotein are achieved through a Q-Sepharose-F-F ion exchange column and an Sephadex G-150 sephadex column, a prepared sea cucumber fucoidan product is fawn, and the sea cucumber glycoprotein is faint yellow. According to the method, a co-production method is adopted, main ingredients such as polysaccharide and glycoprotein in the acaudina molpadioides can be prepared in a jointed mode, emission of waste is reduced in the extraction process, and production cost is lowered.

The invention discloses an acaudina molpadioides processing technology comprising the following technology steps: first-time clear water rinsing, high temperature stewing and shaping, second-time clear water rinsing, bubble massaging cleaning, muscle tissue softness and hardness adjustment, high pressure stewing, ice water soaking, transglutaminase smearing, and storage and package. The acaudina molpadioides processing technology provided by the invention can adjust the softness and the hardness of muscle tissues of the acaudina molpadioides, helps to improve the mouthfeel, can guarantee the individual is not deformed when a preserving environment is changed, and can maintain the elasticity and the mouthfeel of the tissues.

The invention discloses a preparation method of instant acaudina molpadioide leisure food. The preparation method of instant acaudina molpadioide leisure food is characterized by comprising the following steps: removing internal organs of fresh and alive acaudina molpadioides, and cleaning: soaking the acaudina molpadioides in a food-grade organic acid solution with the concentration of 3-5% at 100 DEG C for 20-30 minutes according to the mass ratio of 1: (1-2), filling acaudina molpadioide bodies with the solution circularly by adopting a puncture method, and then filling the bodies with clean water circularly by adopting the puncture method, thus thoroughly removing acid water on walls of the acaudina molpadioide bodies; soaking the acaudina molpadioides into a tea solution at 60-80 DEG C for 8-12 minutes, and filling the acaudina molpadioide bodies with the solution circularly by adopting the puncture method for deodorizing; soaking the acaudina molpadioides into a seasoning liquid, and filling circularly by adopting the puncture method, so that the seasoning liquid rapidly permeates into the walls of the acaudina molpadioide bodies; and taking out the acaudina molpadioides, and draining off, drying in hot air at 40-50 DEG C until the water content is 60-70%, cooling to normal temperature, and carrying out vacuum packaging, thereby obtaining the finished products of the instant acaudina molpadioide leisure food. The preparation method of the instant acaudina molpadioide leisure food has the advantages of capability of removing fishy smell and surface heavy metal of the acaudina molpadioides, long guarantee period, high finished product yield, and convenience in processing and eating.

The invention relates to a preparation method of antioxidative peptide of acaudina molpadioides. Research of preparation of the antioxidative peptide of acaudina molpadioides by autolysis and composite enzymatic hydrolysis of protease at present is less. The method comprises the steps of chopping and cutting up the cleaned acaudina molpadioides below 4 DEG C, adding isometric deionized water to mix evenly, adjusting the pH value to 5.0-7.0, carrying out autolysis and enzymolysis for 8-14 hours at 45-60 DEG C, then boiling and sterilizing for 10-20 minutes; adjusting the pH value to 6.0-7.0, adding 1000-5000U / g of protease; carrying out water bath and hydrolysis for 6-12 hours at 40-60 DEG C, and carrying out water bath and enzyme deactivation for 10-20 minutes at 80-100 DEG C; centrifuging and taking upper clear solution, ultra-filtering the upper clear solution by an ultra-filtration membrane technology; finally carrying out rotary evaporation and concentration at 50-60 DEG C, freezing and drying in vacuum to prepare the product. The polypeptide prepared by the invention is good in water-solubility, low in molecular weight, easy to be absorbed by a human body, and stable in anti-oxidization activity, and has the effect of delaying senescence.

The invention belongs to the technical fields of immunity enhancement and health care, and particularly relates to instant porridge for preventing chemotherapy intestinal catarrh and a preparation method of the instant porridge. The instant porridge is prepared from the following raw materials in parts by weight: 40-50 parts of millet, 15-20 parts of oat, 30-40 parts of red beans, 10-15 parts of pumpkins, 10-15 parts of sweet potatoes, 40-50 parts of Chinese yams, 6-8 parts of asparagus, 10-15 parts of walnut kernels, 4-5 parts of Chinese wolfberry fruits, 2-3 parts of honey, 6-8 parts of 50KD acaudina molpadioides fucoidan, 1-3 parts of lactic acid bacteria powder, and 300-500 parts of pure water. The instant porridge can effectively prevent intestinal catarrh caused by chemotherapy, maintain normal small intestine organizational structures and regulate intestinal flora, has obvious effect of improving the condition that the function of intestines is low caused by chemotherapy, and improves the living quality of patients suffering from tumor chemotherapy. The functional components of the instant porridge are from natural marine feed components, and the instant porridge is free from toxic and side effects, mature in preparation method, and suitable for large-scale industrial production.

The invention relates to a marine food product processing method, in particular to a processing method of seasoning instant acaudina molpadioides. The processing method comprises the following steps of: removing internal organs and surface mud from fresh acaudina molpadioides; naturally unfreezing frozen acaudina molpadioides, and removing internal organs and surface sediments; soaking dry acaudina molpadioides with tap water at the normal temperature for 1-2 days, and removing internal organs and surface mud after the dry acaudina molpadioides become soft by absorbing water; and performing enzyme digestion for peeling, cooking, fermenting at a low temperature, performing secondary enzyme digestion for peeling, performing enzyme deactivation, dicing, seasoning at a low temperature, drying, dehydrating, packaging in vacuum, sterilizing and cooling. An acaudina molpadioides product prepared by processing has the characteristics of no fishy smell, good mouthfeel, no adding of any preservative, long shelf life, good taste, safety, convenience, low cost and the like, and has the characteristics of readiness for eating after bag opening, convenience in carrying, and the like.

The invention discloses a method for fermenting fish sauce from acaudina molpadioides semper. The method comprises steps as follows: (1), the acaudina molpadioides semper, shrimp heads and oyster meat are pulped, salt is added in the pulping process, and fermentation is performed for 3-5 days; (2), protease is added for hydrolysis for 5-8 days; (3), by-products of aquatic product processing are mixed with soy leaven, salt is added and stirred, and mixed fermentation is performed for 40-50 days; (4), aspergillus oryzae strains are inoculated, fermentation is performed for 40-50 days, and a fermentation broth is obtained through filtration; (5), yeast is added to the fermentation broth in the step (4), and then the fermentation broth is stirred uniformly and fermented for 40-50 days; (6), the fermentation temperature is decreased to 20-25 DEG C, and the fermentation is performed for 3-4 months; (7), filtering, sterilization and filling are performed, and a finished product is obtained. On the basis of combination of a traditional fish sauce fermentation technology, the method is improved, a low-salt state is kept in the whole fermentation process, and the hard problem of fishiness in fish sauce preparation is solved. With the adoption of the method, the fermentation time is short, and the prepared fish sauce has unique flavor, abundant nutrition and a certain healthcare function.

The invention relates to acaudina molpadioides semper leisure food and a processing method thereof, and belongs to the technical field of ready-to-eat marine product processing. The acaudina molpadioides semper leisure food is prepared by the following process flows: unfreezing raw materials; cleaning and removing internal organs; soaking in water for the first time; peeling for the first time; performing high-pressure treatment for the first time; soaking in the water for the second time; performing high-pressure treatment for the second time; peeling for the second time; performing enzyme deactivation; soaking in the water for the third time; flavoring; packaging; performing sterilization; and performing refrigeration, wherein ecdysial fluid used in the steps of peeling for the first time and peeling for the second time comprises the following components in percentage by weight: 0.2 to 0.4 percent of papain and 0.002 to 0.004 percent of enzyme special for peeling sea cucumbers. The invention relates to a deep processing method of acaudina molpadioides semper, which can increase the additional value of the acaudina molpadioides semper. The acaudina molpadioides semper, which is not developed and utilized, serves as the raw material, and the captured fresh sea cucumbers are subjected to quick-freezing treatment, so that the nutritional value of the sea cucumbers is maintained maximally; meanwhile, the step of drying the sea cucumbers is omitted, so that the ready-to-eat sea cucumber product has better taste and is convenient to eat.

The invention discloses a method for preparing fish sauce through fermentation of acaudina molpadioides. The method comprises the following steps: (1) pulping acaudina molpadioides, shrimp heads and oyster meat, and simultaneously adding table salt for fermenting for 3-5 days in the pulping process; (2) adding protease for hydrolyzing for 5-8 days; (3) mixing aquatic product processing by-products with soy leaven, adding table salt, stirring, and carrying out mixed fermentation for 40-50 days; (4) inoculating an aspergillus oryzae strain for fermenting for 40-50 days, and filtering, so as to obtain a fermentation liquid; (5) adding yeast into the fermentation liquid obtained in the step (4), uniformly stirring, and fermenting for 40-50 days; (6) decreasing the fermentation temperature to be 20-25 DEG C, and fermenting for 3-4 months; and (7) filtering, and carrying out sterilization and encapsulation, so as to obtain the finished product. The method for preparing the fish sauce through the fermentation of acaudina molpadioides is improved based on a traditional fish sauce fermentation process, and the whole fermentation process is in a low salt state, so that the problem of stinking smell which is difficult to remove in the preparation process of the fish sauce is solved. The method has the beneficial effects that the fermentation time is short, and the prepared fish sauce has unique flavor and rich nutrients as well as a certain health function.

The invention relates to a preparation method for acaudina molpadioides collagen emulsion and belongs to the technical field of emulsion preparation. The method comprises the following steps: preparing acaudina molpadioides collagen, preparing an aqueous phase solution, preparing an oil phase solution and emulsifying. The acaudina molpadioides collagen emulsion prepared according to the invention is free from chemical addition, has excellent moisturizing and whitening skincare effects, can make skin smooth and bright after long-term use and is suitable for allergic people.

The invention discloses a peeling and cleaning device for acaudina molpadioides semper. The peeling and cleaning device comprises an outer cylinder, an inner cylinder and a motor, acaudina molpadioides semper is placed in the inner cylinder; the inner cylinder comprises a cylinder cover, a cylinder body and a base, a plurality of buffing brushes are arranged around the cylinder body and are parallel to the direction of the inner wall of the cylinder body, rugged and bulged sand trays are arranged on the surface of the base, the cylinder body and the base are integrally connected or not in contact with each other, and the buffing brushes are integrally connected with the inner wall of the cylinder body or not in contact with the inner wall of the cylinder body. The peeling and cleaning device for acaudina molpadioides semper, provided by the invention, is diverse in design, and ingenious and reasonable in structure, has a good acaudina molpadioides semper buffing effect, is thorough in cleaning, and fully meets the requirements of pretreatment of acaudina molpadioides semper.

The invention discloses a traditional Chinese medicine cataplasma for treating autoimmune thyroiditis, and a preparation method of the traditional Chinese medicine cataplasma. The effective components of the traditional Chinese medicine cataplasma are prepared from the following raw materials in parts by weight: 45-55 parts of thunberg fritillary bulb, 15-25 parts of Chinese yam, 5-10 parts of radix isatidis, 8-15 parts of albizia flower and 5-10 parts of acaudina molpadioides. The invention further discloses a preparation method of the traditional Chinese medicine cataplasma. An experiment result proves that the traditional Chinese medicine cataplasma disclosed by the invention has a good treatment effect on the autoimmune thyroiditis, is good in transdermal absorption effect, has the advantages of rapidly releasing medicines and rapidly playing medicine effects, and has good clinical application value; and metabolism of the medicine in gastrointestinal tracts can be avoided.

The invention relates to a rapid extraction method for total RNA of an acaudina molpadioides digestive tract. At present, a sample is relatively difficult to process before the total RNA of the acaudina molpadioides digestive tract is extracted, the extraction yield of the total RNA is not high, and the total RNA is easy to pollute. The method comprises the following steps of: grinding a liquid nitrogen frozen acaudina molpadioides digestive tract tissue by using a mortar, putting the powder into TRIZOL lysis solution for lysis and homogenization; homogenizing and centrifuging the tissue, taking supernatant fluid, adding chloroform, shaking, blending, centrifuging and taking the supernatant fluid; adding low temperature isopropyl alcohol, blending, and centrifugating; washing by using 75 percent of ethanol; and dissolving precipitates by using RNA (Ribose Nucleic Acid) enzyme-free deionized water, and preserving at the temperature of between -90 and -70 DEG C. According to the method, the RNA degradation of the sample is effectively avoided, the RNA precipitation effect is improved, the extracting time is short, the RNA integrity is high, and the requirement of real-time quantitative PCR (polymerase chain reaction) detection is completely met.

The present invention discloses an acaudina molpadioides peel polishing and cleaning apparatus which includes an outer cylinder, an inner cylinder and an electric motor. The acaudina molpadioides is placed in the inner cylinder; the inner cylinder includes a cylinder cover, a cylinder body and a base; a number of peel polishing brushes are arranged around the cylinder body and parallel to the direction of the cylinder inner wall, the base is a sand tray and the surface is provided with uneven protrusions. The acaudina molpadioides peel polishing and cleaning apparatus is various in designs, and ingenious and reasonable in structures, has good acaudina molpadioides peel polishing effects, can clean the acaudina molpadioides very well, and fully meet the pre-treatment needs of acaudina molpadioides.

A method for detecting and counting the biomass of acaudina molpadioides larvae in seawater comprises the following steps of: extracting acaudina molpadioides adult DNA, and sequencing to obtain a COIgene sequence; manufacturing standard substances with four concentration gradients by taking a PCR product as an initial standard substance; designing and verifying fluorescent quantitative PCR specific primers, and obtaining a standard curve of CT value-DNA concentration logarithm values after verification is passed; extracting DNA from acaudina molpadioides tissues with different dry weights, and performing fluorescent quantitative PCR quantitative test by taking the DNA of the acaudina molpadioides tissues with different dry weights as a template, so that a trend linear equation of DNA quality and acaudina molpadioides tissue dry weights is obtained; measuring a CT value of DNA in a seawater sample to be measured, substituting the CT value into a acaudina molpadioides tissue dry weight-CT value derivation relational expression, so that a concentration value of acaudina molpadioides larva DNA is obtained, and calculating to obtain the DNA mass of the acaudina molpadioides larva; andcalculating the wet weight of the acaudina molpadioides larva through the dry-wet weight ratio and the derivation relational expression.

A device for extracting polysaccharide from acaudina molpadioides is provided, which includes a mixing box, a blocking cover, a feed pipe group, a discharge pipe, a bottom plate, a side plate, a first motor, a first transmission shaft, two drive shafts, a first circular gear, two second circular gears, two rotary discs, two connecting frame groups, two semiarc rotary discs, a slide bar, a stop collar, a fixed link, a baffle, a first bushing group and a first sleeve spring group. A top side wall and a rear lower side of the mixing box are communicated with the feed pipe group and the discharge pipe, respectively. Front side and rear sides of the slide bar are longitudinally connected with multiple first engaging teeth. Both the two semiarc rotary discs are connected with multiple second engaging teeth. The fixed link is connected between the stop collar and the slide bar.

The invention discloses a preparation method of instant acaudina molpadioide leisure food. The preparation method of instant acaudina molpadioide leisure food is characterized by comprising the following steps: removing internal organs of fresh and alive acaudina molpadioides, and cleaning: soaking the acaudina molpadioides in a food-grade organic acid solution with the concentration of 3-5% at 100 DEG C for 20-30 minutes according to the mass ratio of 1: (1-2), filling acaudina molpadioide bodies with the solution circularly by adopting a puncture method, and then filling the bodies with clean water circularly by adopting the puncture method, thus thoroughly removing acid water on walls of the acaudina molpadioide bodies; soaking the acaudina molpadioides into a tea solution at 60-80 DEG C for 8-12 minutes, and filling the acaudina molpadioide bodies with the solution circularly by adopting the puncture method for deodorizing; soaking the acaudina molpadioides into a seasoning liquid, and filling circularly by adopting the puncture method, so that the seasoning liquid rapidly permeates into the walls of the acaudina molpadioide bodies; and taking out the acaudina molpadioides, and draining off, drying in hot air at 40-50 DEG C until the water content is 60-70%, cooling to normal temperature, and carrying out vacuum packaging, thereby obtaining the finished products of the instant acaudina molpadioide leisure food. The preparation method of the instant acaudina molpadioide leisure food has the advantages of capability of removing fishy smell and surface heavy metal of the acaudina molpadioides, long guarantee period, high finished product yield, and convenience in processing and eating.

The invention provides a method for preparing sea cucumber fucoidan and sea cucumber glycoprotein. According to the method, acaudina molpadioides serves as the raw material, a mild stepped enzymolysis processing method is mainly adopted, an ultrafiltration membrane is utilized to separate out a mixture of crude polysaccharide and glycoprotein, then separation, purification and preparation of the sea cucumber fucoidan and the sea cucumber glycoprotein are achieved through a Q-Sepharose-F-F ion exchange column and an Sephadex G-150 sephadex column, a prepared sea cucumber fucoidan product is fawn, and the sea cucumber glycoprotein is faint yellow. According to the method, a co-production method is adopted, main ingredients such as polysaccharide and glycoprotein in the acaudina molpadioides can be prepared in a jointed mode, emission of waste is reduced in the extraction process, and production cost is lowered.

The invention discloses acaudina molpadioides semper nutritional health-care meat balls which are made from, by weight, 25-45 parts of smashed acaudina molpadioides simper, 25-35 parts of minced pork, 10-25 parts of smashed okra, 15-25 parts of starch, 1-2 parts of edible gum and 5-10 parts of seasonings. The invention further discloses a making method of the acaudina molpadioides semper nutritional health-care meat balls. According to the acaudina molpadioides semper nutritional health-care meat balls, acaudina molpadioides simper and okra are added, and the meat balls are environmentally friendly, healthy, novel, balanced and rich in nutrient, good in look, smell and taste and convenient to eat, have the health-care effect and meet requirements of mass customers. The making method of the meat balls is simple, practical, scientific and reasonable, nutrient value of materials can be maintained, and the method is suitable for industrial production and application.

The invention relates to a wrinkle-removing skin lotion with a whitening effect and a preparation method thereof, belonging to the technical field of cosmetic preparation. The preparation method comprises the following steps: with bighead atractylodes thizomes, rhizoma bletillae, poria cocos and Chinese angelica roots as raw materials, crushing the raw materials, respectively and sequentially soaking the crushed raw materials in an acid solution and an alkaline solution for detoxification; mixing the detoxified crushed traditional Chinese medicine materials with absolute methanol, and carryingout extracting to obtain a composite traditional Chinese medicine extract; with acaudina molpadioides as a raw material, soaking acaudina molpadioides with a sodium chloride solution to remove non-collagenous proteins; adding a microbial enzyme for an enzymolysis reaction, and carrying out extracting to obtain collagen polypeptide, namely self-made wrinkle-removing liquid; and finally mixing thecomposite traditional Chinese medicine extract, the self-made wrinkle-removing liquid and other auxiliary materials to finally obtain the wrinkle-removing skin lotion with the whitening effect. The wrinkle-removing skin lotion has excellent wrinkle-removing and whitening functions and good application prospects.

The invention provides a preparation method of acaudina molpadioides and camel blood hypoglycemic peptide. The acaudina molpadioides and camel blood hypoglycemic peptide comprises the following components in parts by weight: 1-9 parts of acaudina molpadioides polypeptide and 1-9 parts of camel blood polypeptide. The acaudina molpadioides and the camel blood are used as raw materials; the acaudinamolpadioides hypoglycemic peptide and the camel blood hypoglycemic peptide are prepared through protease enzymatic hydrolysis, membrane separation, and other technologies, the acaudina molpadioides hypoglycemic peptide and the camel blood hypoglycemic peptide are mixed in a proper proportion, and the acaudina molpadioides and camel blood hypoglycemic peptide is prepared and can reduce blood sugar.The preparation method is green and environment-friendly, realizes high-valued utilization of camel blood and acaudina molpadioides, has a wide market prospect, and can generate good economic and social benefits.

The invention relates to a method for identifying isostichopus badionotus through specific peptide fragment sets and marker peptide. When one set of marker peptide is used independently or combined for use, the marker peptide can be used for identifying the isostichopus badionotus. The marker peptide is a low-homology polypeptide fragment of isostichopus badionotus protein, the low-homology polypeptide fragment means that the peptide fragment is particular to the isostichopus badionotus, and the length of the polypeptide fragment is 5-30 pieces of amino acid. Even though it is found that part of the protein is consistent with plant or bacteria and other species, when the isostichopus badionotus is compared with thelenota ananas, acaudina molpadioides, stichopus japonicas and isostichopus fuscus, the marker peptide is particular to the isostichopus badionotus.

The present invention relates to a method for identifying Haitian melon (Acaudina molpadioides) by using a specific peptide group, and a group of control polypeptides for identifying Haitian melon by mass spectrometry. The sequence of the polypeptide is: SEQ ID NO.1-5 : No expression seen in other species.

The invention discloses a preparation method of acaudina molpadioides semper biologically active peptide. The preparation method comprises the following steps of (1) mashing acaudina molpadioides semper; (2) domesticating microorganisms; (3) performing microorganism fermentation and degradation; (4) performing enzymolysis; and (5) performing centrifugation, and taking supernatant to obtain a bioactive peptide solution. The acaudina molpadioides semper is used for developing further comprehensive utilization, pollution abatement is facilitated, the added value of by-products is increased, and yield increasing and effect increasing during breeding are promoted. In the preparation technology, based on current research, the technology steps are improved, the technology time is shortened, collagen in the acaudina molpadioides semper is changed into polypeptide, the extraction rate of the polypeptide in the acaudina molpadioides semper is further increased, and the content of polypeptide being high in bioactivity and small in molecular weight in prepared polypeptide is greatly increased, and the ratio of short chain polypeptide of which the molecular weight is smaller than 1KDa is 83.17%.

The invention provides blood-pressure-lowering acaudina molpadioides peptides and granules prepared from the blood-pressure-lowering acaudina molpadioides peptides. Acaudina molpadioides is adopted for preparing the blood-pressure-lowering acaudina molpadioides peptides; and then, the prepared blood-pressure-lowering acaudina molpadioides peptides are used as an active ingredient for preparing granules, and thus, the prepared granules have an auxiliary function of lowering blood pressure. The acaudina molpadioides is adopted as a raw material, and active acaudina molpadioides polypeptides areprepared from the acaudina molpadioides so that the raw materials are safe and environmentally friendly. Being orally taken, the active acaudina molpadioides polypeptides are capable of lowering bloodpressure as an auxiliary treatment; moreover, the active acaudina molpadioides polypeptides have a plurality of physiological activities so that the blood-pressure-lowering acaudina molpadioides peptides can be taken as an active ingredient used for preparing granules which have good market prospects. The invention further provides a preparation method of the blood-pressure-lowering acaudina molpadioides peptide granules which is simple in processes, good in controllability, easy to operate and implement, and conducive to large-scale industrial production; and thus, the preparation method ofthe blood-pressure-lowering acaudina molpadioides peptide granules has wide application prospects and good economic benefits.

The invention provides a sea cucumber polysaccharide and sea cucumber collagen polypeptide combined preparation method. The sea cucumber polysaccharide and sea cucumber collagen polypeptide combined preparation method includes subjecting Acaudina Molpadioides serving as a raw material to mild two-stage enzymolysis treatment and obtaining Acaudina Molpadioides polypeptide mixed liquor and Acaudina Molpadioides polysaccharide mixed liquor by an ultrafiltration membrane separation technology; selecting ultrafiltration membranes different in molecular weight cut-off to achieve graded separation of Acaudina Molpadioides polypeptide and Acaudina Molpadioides polysaccharide so as to obtain Acaudina Molpadioides polypeptide products with three molecular weights and Acaudina Molpadioides polysaccharide products with four molecular weights. The sea cucumber polysaccharide and sea cucumber collagen polypeptide combined preparation method has the advantages that sea cucumber polypeptide and sea cucumber polysaccharide products different in molecular weight in Acaudina Molpadioides can be prepared in a combined manner, so that waste discharge during extraction is reduced and production cost is lowered.