The invention relates to an intestinal motility medicinal composition, which is prepared from the following components in part by weight: 50 parts of Chinese pasque herb, 50 parts of parslane herb, 75 parts of wrinkled gianthyssop herb, 25 parts of meadowrue root and rhizome, 35 parts of medicine terminalia fruit, 25 parts of alum, 50 parts of Chinese white poplar, 30 parts of bistort rhizome and30 parts of szechuan tangshen root. The intestinal motility medicinal composition has the characteristics of obvious medicinal effect, low using cost, no toxic or side effect and the like. After the intestinal motility medicinal composition is used, the phenomena of dying of fish, shrimps and crabs are reduced obviously, and the immune resistance of organisms is improved. After the intestinal motility medicinal composition is used continuously, death caused by severe bottom environment in the middle and later periods of aquaculture can be prevented, the aquaculture yield and success rate are improved, and the economic benefits of farmers are ensured fully. Simultaneously the intestinal motility medicinal composition is a pure Chinese medicinal preparation, has no toxic or side effect and avoids medicinal residues in animal bodies, so the food quality of fish, shrimp and crab products is ensured.