7 results about "Ketone concentration" patented technology

This invention discloses a respiratory mask with multi-parameter detection capabilities, comprising: a main body of the respiratory mask and multiple sensors connected thereto; the multiple sensors include at least a carbon dioxide sensor, a pH sensor, and a ketone body sensor, used to detect the carbon dioxide concentration, pH value, and ketone body value in the patient's exhaled gas, respectively; the main body of the respiratory mask is provided with a one-way inlet valve and a one-way outlet valve, the one-way outlet valve being connected to one end of the outlet pipe to guide the exhaled gas to the outlet pipe; the carbon dioxide sensor and the ketone body sensor are both connected to one end of the outlet pipe; the main body of the respiratory mask is provided with a condensation structure to condense water vapor in the exhaled gas into condensate, and the condensate is transported to the pH sensor for detection through a condensate collection pipe. This invention can simultaneously detect multiple parameters, is simple and convenient to operate, and has high sensitivity, which helps to improve the accuracy of disease diagnosis.

An object of the present application is to provide a new composition for promoting ketogenesis. According to the present application, there is provided a composition for promoting ketogenesis containing one or two or more amino acids selected from the group consisting of citrulline, leucine, cysteine, taurine, glutamine and aspartic acid. The composition of the present application can further contain either or both of a medium-chain fatty acid and a medium-chain fatty acid ester.

This application discloses an implantable dual-channel monitoring sensor and its fabrication method. The sensor includes a substrate and an electrode assembly, a sensing component, and a functional component disposed on the substrate. The sensing component includes a glucose sensing layer and a ketone body sensing layer, and the functional component includes a first functional film layer and a second functional film layer. The electrode assembly includes a first working electrode, a second working electrode, a reference electrode, and a counter electrode. The first working electrode has a glucose sensing layer disposed on it, and the second working electrode has a ketone body sensing layer disposed on it. The first functional film layer encapsulates the glucose sensing layer, and the second functional film layer encapsulates the ketone body sensing layer. This application enables dual-channel collaborative continuous monitoring and seamless integration of the two monitoring data. Furthermore, this implantable dual-channel monitoring sensor has low design cost, simple manufacturing process, and mass production advantages.

An organoleptically acceptable composition containing a ketone body or a ketone body precursor including a hydroxybutyrate ester and a flavouring is provided and gives improved palatability and user adherence to the intended dose regime. The flavouring may be a bitter flavouring and the composition may further contain an adsorbent for the ketone such that on ingestion, the bitterness of the composition may be masked. The composition may be in the form of a solid, gel or liquid and provides increased blood ketone levels and may be used in therapy or in treating muscle impairment or fatigue.

Use of a ketone body and a ketone body ester for preserving glycogen and / or protein, thereby reducing muscle breakdown and improving endurance during exercise and promoting muscle recovery following exercise. Also for retarding muscle wasting in aging and disease. (R)-3-hydroxybutyl (R)-3-hydroxybutyrate for use in reducing muscle glycogen and protein breakdown during exercise or decreasing muscle wasting in aging and disease. Certain esters of hydroxybutyrate monomers, particularly a monoester of D-β-hydroxybutyrate with R-1,3-butanediol or with glycerol to reduce muscle breakdown and aid muscle recovery after exercise or retard muscle wasting. Compositions containing the ketone bodies or ketone body esters are also described.

The present invention relates to non-invasive methods of diagnosing primary aldosteronism (PA), preferably in subjects in need of such diagnosis. As described herein, it was discovered that the concentration of plasma parathyroid hormone (PTH) in blood samples isolated from subjects was predictive of a diagnosis of primary aldosteronism depending on the plasma aldosterone concentration (PAC), plasma renin concentration (PRC), and plasma renin activity (PRA). Preferably PAC, PRC, and PRA are measured from the same blood sample as the concentration of plasma parathyroid hormone.

A ketogenic R-beta-hydroxybutyrate mixed salt-acid composition includes enantiomerically pure R-beta-hydroxybutyric acid and one or more enantiomerically pure R-beta-hydroxybutyrate salts. The R-beta-hydroxybutyric acid is more rapidly absorbed and utilized by the body than salts or esters, enhances taste, and reduces the need to include citric acid or other edible acids. The enantiomerically pure R-beta-hydroxybutyrate salt(s) are more slowly absorbed and utilized by the body and can provide one or more electrolytes. Compositions for increasing ketone body level in a subject may contain a dietetically or pharmaceutically acceptable carrier and an R-beta-hydroxybutyrate mixed salt-acid composition. The composition contains less than 100% by molar equivalents of total enantiomerically pure R-beta-hydroxybutyrate salts and more than 0% by molar equivalents of enantiomerically pure R-beta-hydroxybutyric acid.