The invention discloses a preparation method of goose meat, skin and bone mixed luncheon meat, which is characterized in that raw material components contain goose meat, goose skins and goose bones, and formula components contain transglutaminase (TG). The method comprises the following steps of: selecting and pretreating goose meat, goose skins and goose bones; pickling the goose meat, the goose skins and the goose bones; adding the goose meat and bone meal mixed meat paste, carrying out chopping on the obtained mixture; adding compound phosphate, and carrying out chopping on the obtained object; adding the goose skins, and carrying out chopping on the obtained object; adding pigments and spices, and carrying out chopping on the obtained object; adding starches and soy isolate proteins, and carrying out chopping on the obtained object; adding the TG, and carrying out chopping on the obtained object; carrying out weighing and die-filling on the obtained product; and sequentially carrying out TG enzyme reaction, enzyme deactivation, ripening, cooling, packaging and sterilization on the obtained product. According to the invention, the goose meat, skin and bone mixed luncheon meat is prepared by using the cross-linking effect of TG, therefore, the product form of goose products is enriched, the utilization rate of goose by-products is improved, and finally obtained products are not only better in flavor, good in taste, elastic, and good in water retention, but also has the characteristics of low fat content, high protein and high calcium, therefore, the finally obtained products are especially applicable to the crowds with obesity, hyperlipidemia, hypertension and insufficient calcium intake.