3 results about "Oxytetracyclinum" patented technology

The application discloses a high-stability and low-irritation oxytetracycline long-acting injection and a preparation method thereof. 2+ EDTA-2Na and sodium formaldehyde bisulfite are coordinated to stabilize, and forsythia extract reduces irritation; the pH of the finished product is 8.2-8.8. The method comprises acid pre-coordination, pre-filtration, ultrafiltration, reduction and deoxygenation (dissolved oxygen is less than or equal to 2 ppm) and 0.22 mu m terminal sterile filtration. The application realizes long-term clarification and content stability under high loading, and inhibits metal catalytic oxidation and alkali-sensitive degradation.

The application provides a preparation method of a heterostructure nano-enzyme and application of the heterostructure nano-enzyme, and the heterostructure nano-enzyme is FeMoO4@Fe7S8, and the preparation method comprises the following steps: dissolving Na2MoO4.2H2O, oxalic acid and thiourea in ultrapure water to form a solution A; mixing FeCl3.6H2O, NaAc and anhydrous ethylene glycol to form a solution B; reacting the mixed solution obtained by uniformly mixing the solution B and the solution A at 195-205 DEG C for 20-30 h; and drying the product after cleaning with anhydrous ethanol and ultrapure water. The heterostructure nano-enzyme solves the aggregation problem of FeMoO4 nanoparticles. The heterostructure nano-enzyme is a peroxidase-like enzyme, has high enzyme-like catalytic activity, has good affinity to H2O2 and TMB, and has high stability. The heterostructure nano-enzyme has universality in catalyzing color development of a color developing substrate, has a wide linear range in oxytetracycline detection, has a low detection limit, is simple to operate, and has low detection cost.