42 results about "P-nitroanisole" patented technology

The invention relates to a method for preparing p-aminoanisole by catalytic hydrogenation of an industrial-scale device, which is to add raw materials to p-aminoanisole continuously or intermittently during each production cycle in an industrial-scale hydrogenation kettle. Nitroanisole, and real-time monitoring of the concentration of raw materials and impurities in the hydrogenation tank during the reaction to obtain p-aminoanisole with a purity of more than 99.5% and a yield of 100%. The p-aminoanisole product obtained by the present invention has a purity of more than 99.5%, and can be used and sold directly; it can also be further rectified to obtain a p-aminoanisole product with a purity of more than 99.9%, which can be used in special fields.

The invention discloses a clean production method of p-anisidine. The clean production method comprises the following steps of (1) enabling nitrochlorobenzene, sodium hydroxide and methanol to be subjected to an etherification reaction so as to obtain etherification reaction liquid; (2) directly filtering the etherification reaction liquid obtained in the step (1) to obtain a filtrate and filter cakes, washing the filter cakes with the methanol, drying the washed filter cakes to obtain industrial-grade sodium chloride, and distilling the filtrate so as to obtain p-nitroanisole concentration liquid; and (3) under the condition that a hydrogenation catalyst exists, enabling the p-nitroanisole concentration liquid obtained in the step (2) to be subjected to a hydrogenation reduction reaction in the hydrogen atmosphere, and after the reaction is completed, performing after-treatment so as to obtain the p-anisidine. According to the clean production method, after the etherification reaction is finished, direction filtration is performed so that the sodium chloride is removed, then concentration treatment is performed on the etherification reaction liquid, the hydrogenation reaction is directly performed, the operation is simple and convenient, and the yield and the purity of the obtained product are high.

A process for preparing o-nitro phenylmether, p-nitro phenylmether and meta-nitro chlorobenzene from chlorobenzene includes such steps as nitrifying reaction to obtain the nitro chlorobenzene mixture, etherifying reaction in etherifying agent, separating, and refining to obtain said products.

The invention discloses a method for preparing p-anisidine through catalytic hydrogenation of p-nitroanisole. According to the method, p-nitroanisole is used as a reaction raw material and subjected to a reaction in an enclosed reactor with a mechanical stirring function under the conditions of usage of a composite catalyst, no usage of a solvent, a reaction temperature of 80 to 150 DEG C and hydrogen pressure of 0.3 to 1 MPa so as to obtain p-anisidine, wherein the composite catalyst is composed of active components metal M and a carrier; the active components metal M are composed of two or more selected from a group consisting of Cu, Ni, Fe, Zn, Co, Cr and Mo, and the content of the active components metal M accounts for 0.3 to 25 wt% of the mass of the composite catalyst; and the carrier is prepared by compounding a carbon-containing organic matter and an inorganic oxide, a mass ratio of the carbon-containing organic matter to the inorganic oxide is 1: 50 to 1: 10, and the inorganicoxide is any one selected from a group consisting of SiO2, Al2O3, MgO, TiO2, CeO2 and a 4A molecular sieve. The composite catalyst used in the invention has high catalytic activity, stable performance and high selectivity and conversion rate.

The invention discloses a synthesis method of 2-amino-4-acetamino anisole. The synthesis method comprises the following steps: (1) carrying out a primary catalytic hydrogenation reduction reaction onp-nitroanisole and hydrogen in the presence of a catalyst A to obtain p-methoxyaniline; (2) carrying out an acetylation reaction on the p-methoxyaniline to obtain p-acetanisidine; (3) carrying out a nitration reaction on the p-acetanisidine to obtain 2-nitro-4-acetamino anisole; and (4) carrying out a secondary catalytic hydrogenation reduction reaction on the 2-nitro-4-acetamino anisole and hydrogen in the presence of a catalyst B to obtain 2-amino-4-acetamino anisole. 2-amino-4-acetamino anisole is synthesized by using a method sequentially comprising acylation, nitration and reduction, so that the problems that raw materials are easily oxidized, the amount of side reactions is large and a product is difficult to separate and low in purity in a traditional directional acylation process are avoided; and the purity of the product synthesized by using the method disclosed by the invention can reach 99.5%-99.8%.