41results about How to "Green synthesis" patented technology

The invention provides a method for synthesizing silver nanoclusters by the aid of single-stranded DNA (deoxyribonucleic acid) used as a template, and belongs to the technical field of nano materials. By the method, problems of complicated production and excessively high cost of nano-silver for detecting mercury ions at present are solved. The method for synthesizing the silver nanoclusters by the aid of the single-stranded DNA used as the template is characterized in that the single-stranded DNA containing cytosine and guanine is used as the template and is mixed with Ag<+> solution to obtain a mixture, reducing agents are added into the mixture, and the fluorescent silver nanoclusters can be acquired after reduction reaction is performed on the mixture with the reducing agents. The method has the advantages that polyinosinic acid (PI) and polycytidylic acid (PC) which are commercially available are used as the template in the simple, low-cost, environment-friendly and reliable method for synthesizing the silver nanoclusters; fluorescence is utilized, and fluorescent silver nanocrystals are synthesized from the polyinosinic acid, the polycytidylic acid and the like without special design or preprocessing; and the novel silver nanoclusters are excellent in selectivity and sensitivity, can be applied to detecting Hg<2+>, and are feasible and have a future development prospect in the aspect of monitoring pollutants in water.

The invention relates to a method for synthesizing paranitroanisole. The raw materials used by the method are green chemicals dimethyl carbonate (DMC) and p-nitrophenol, and the catalyst is NaY molecular sieve, activated aluminum oxide or activated carbon which is impregnated by alkali metals or alkaline-earth metal compounds. Good conversion rate of the raw materials and good selectivity of target products can be obtained by using the method provided by the invention under the reaction conditions that: the temperature is between 90 and 200 DEG C, and the reaction time is between 1 and 5 hours; the mol ratio of the p-nitrophenol to the dimethyl carbonate of the raw materials is between 1 to 5 and 1 to 15, and the amount of the catalyst is 2 to 20 percent of the mass of the raw materials, wherein, the conversion rate of the p-nitrophenol can reach over 64 percent, and the selectivity of the paranitroanisole can reach 100 percent. The method takes the DMC as a methylated reagent to actually realize a green synthetic route, takes solid alkali as the catalyst, and is superior to the prior synthetic method of homogeneous catalysis or phase-transfer catalysis; and the catalyst is simple to separate and can be reused.

The invention discloses a preparation method of a 1,3-diene derivative having aggregation-induced emission property and belongs to the technical field of synthesis of compounds. The derivatives have strong aggregation-induced emission property and the preparation of the derivatives is achieved by carrying out oxydehydrogenation coupling reaction on a substrate olefin under the catalysis of palladium in the presence of oxygen serving as an oxidant. The method has the characteristics of mild reaction condition, simple operation, use of easily available raw materials, high selectivity and environmental friendliness and is used for solving the deficiencies in the prior art that the synthetic efficiency of the compounds having the aggregation-induced emission property is low and the cost is high.

The invention provides a laser preparation method of a CoOOH nanosheet with rich oxygen vacancies. The laser preparation method comprises the following steps of: carrying out surface treatment on a metal cobalt target; placing the metal target in alkaline solution well-blended in advance, and utilizing nanosecond laser to irradiate for 20 minutes under room temperature till the solution is changedinto brown sol; using deionized water to wash the brown sol multiple times, then freezing and drying for 24 hours and obtaining the CoOOH nanosheet with rich oxygen vacancies. The laser preparation method provided by the invention has the beneficial effects that the metal target is used as a precursor, the type is simple, no catalyst is used in the synthetic process, the process is fast and environment-friendly, and side products are fewer, so that the catalytic activity and the conductivity of the material are improved; the method is mild, and can be finished under room temperature; comparedwith the traditional synthetic method, the method realizes great reduction of energy consumption and danger in synthesis; the CoOOH nanosheet is wide in application and is applicable to synthesis ofvarious materials; therefore, the development of the laser liquid-phase method for synthesizing the nano material with rich oxygen vacancies in an environment-friendly, fast and high-efficiency mannerconforms to the needs of the current society for low energy consumption and low pollution in material synthesis.

The invention discloses an environment-friendly synthetic method of a 4-ferrocenyl quinoline derivative. The method is prominently characterized in that ethynylferrocene, aromatic aldehyde and aromatic primary amine generate a three-component cyclization reaction in water under the catalysis of a small amount of organic acid, so as to efficiently synthesize the 4-ferrocenyl quinoline derivative in one step. Compared with the prior art, the environment-friendly synthetic method has the advantages that, heavy metal salt and toxic solvent toluene are not used, the inert gas shielding is not required, reaction conditions are mild, the yield is high, the cost is low, the environmental protection is realized, and the like. A new effective way is provided for rich and structurally diverse quinoline metal derivatives, and the method has wide application prospects.

The invention relates to a method for catalytic synthesis of paranitrophenetole. The raw materials used by the method are green chemicals diethyl carbonate (DMC) and p-nitrophenol, and the catalyst is NaY molecular sieve, activated aluminum oxide or activated carbon which is impregnated by alkali metals or alkaline-earth metal compounds. Good conversion rate of the raw materials and good selectivity of target products can be obtained by using the method provided by the invention under given conditions; and the conversion rate of the p-nitrophenol can reach over 64 percent, and the selectivity of the paranitrophenetole can reach 100 percent. The method is superior to the prior synthetic method of homogeneous catalysis or phase-transfer catalysis; and the catalyst is simple to separate and can be reused. Moreover, the method takes the DEC as an ethylized reagent to actually realize a green synthetic route.

The invention provides a method for producing an amlodipine besylate intermediate by using a micro-reaction device. According to the method, o-chlorobenzaldehyde is used as a raw material, the amlodipine besylate intermediate is rapidly and safely prepared by using the micro-reaction device, and the method has the advantages of high reaction conversion rate, simple post-treatment, small reaction volume, short reaction time, low energy consumption and the like, and has relatively high commercial value.

The invention relates to a preparation method and application of a chiral spiro aminophosphine ligand with a substituent at the 3-position of a pyridine ring. The chiral spiro aminophosphine ligand isa compound shown as a formula 1, or a racemate or an optical isomer thereof, or a catalytically acceptable salt thereof, and is mainly structurally characterized by having a chiral spiroindane skeleton and a pyridine group. The chiral spiro aminophosphine ligand can be synthesized by using a 7-diaryl/alkylphosphino-7'-amino-1,1'-spiroindane compound with a spiro skeleton as a chiral starting material. After the chiral spiro aminophosphine ligand and a transition metal (iridium) salt form a complex, the complex can be used for catalyzing asymmetric catalytic hydrogenation reaction of an alpha-arylamine substituted lactone compound, shows very high catalytic activity (with TON reaching 19000) and enantioselectivity (up to 99% ee), and has practical value.

The invention discloses a synthetic method of an ammonium acetate-mediated benzothiazole compound . The synthetic method comprises the steps: adding an o-haloaniline derivative, potassium sulfide, dimethyl sulfoxide, a catalyst, an additive 1 and an additive 2 into a reaction tube, carrying out a stirring reaction at the temperature of 130-150 DEG C, cooling to room temperature after the reactionis finished, and separating and purifying the product to obtain the benzothiazole compound. The invention provides the synthetic method of the benzothiazole compound by taking K2S as a sulfur source,DMSO as a carbon source and an oxidizing agent, an o-haloaniline derivative as a substrate and an ammonium acetate mediated three-component one-pot method. The method has the advantages of fewer reaction steps, mild reaction conditions, good functional group tolerance and the like.

The invention belongs to the technical field of plant extraction and discloses a method for extracting anthocyanin by utilizing a deep eutectic solvent (DES). The method comprises the following steps: uniformly mixing raw material powder containing anthocyanin with the DES, stirring the materials at 30-60 DEG C for 20-60 minutes to enable the materials to react fully, then taking supernatant through centrifugation, and carrying out elution and drying after the supernatant is adsorbed by a macroporous absorption resin column, thus obtaining anthocyanin powder, wherein the DES is a eutectic mixture of quaternary ammonium salts and hydrogen bond donors in a mole ratio of 1 to (10-19). The method has the beneficial effects that the DES can dissolve anthocyanin more effectively as the solubility parameters of the hydrogen bond donors in the DES are very close to the solubility parameters of the basic structure of anthocyanin, while the phase transfer catalysis effects of the hydrogen bond donors (quaternary ammonium salts) have better promoting effects on dissolution of anthocyanin; and therefore, high-purity anthocyanin can be efficiently purified by utilizing the DES.