45 results about "Polypyrrole nanoparticles" patented technology

The invention discloses a preparation method of a nanometer chemotherapeutic drug carrier. The preparation method comprises the steps that manganese-doped prussian blue nanoparticles and manganese-doped prussian blue@polypyrrole nanoparticles are synthesized firstly, then 4 mg of the manganese-doped prussian blue nanoparticles and the manganese-doped prussian blue@polypyrrole nanoparticles are weighed to be dissolved in a 4 ml of PBS buffer solution, and stirring is conducted to prepare a uniform solution; 1 mg of doxorubicin hydrochloride (DOX) is weighed to be dissolved in a 1 ml of PBS solution and dropped into a nanoparticle solution under the light avoidance condition, and after dropping is finished, 75 mg of sodium hyaluronate is weighed to be added to the solution to be stirred at the low speed for 24 h; and then a dialysis bag with the molecular weight cut-off being 14 KD is selected to conduct light avoidance dialysis for 24 h, and a final product is obtained and placed in a refrigerator at 4 DEG C for light avoidance preservation. The preparation method has great significance in preparing the nanometer chemotherapeutic drug carrier with MRI and PTT functions to load chemotherapeutic drugs, and realizing the nanoparticles with a diagnosis and treatment integrated function.