6 results about "Proton acceptor" patented technology

This document describes a pharmaceutical composition comprising a therapeutic agent, an absorption enhancer, a polymer comprising multiple basic groups, and a non-polymeric (small molecule) proton acceptor. The absorption enhancer is preferably a substituted fatty acid or a salt thereof. This document also describes a method of treating a condition treatable by the therapeutic agent, comprising oral administration of the pharmaceutical composition.

The invention provides a method of continuous electrochemical dinitrogen reduction to produce ammonia, the method comprising: supplying dinitrogen to an electrochemical cell comprising an electrolyte in contact with at least a cathode; introducing protons to the electrolyte by anodic oxidation of a hydrogen-containing species; and cathodically reducing the dinitrogen in the presence of a metal selected from lithium, magnesium, calcium, strontium, barium, zinc, aluminium and vanadium to produce ammonia, wherein the electrolyte comprises a cationic proton carrier capable of reversible deprotonation to form a neutral proton acceptor, wherein the neutral proton acceptor is an ylide.

This invention relates to the field of acyclic or carbocyclic compounds and discloses a method for preparing 6-bromo-2,3-difluorotrifluorotoluene, comprising: dissolving 2,3-difluorotrifluorotoluene in a mixed solvent composed of a polar modifier containing a proton acceptor site and a nonpolar solvent; adding a polyether stabilizer and an iron-based catalyst; and dropwise adding liquid bromine to trigger a directional bromination reaction. The method utilizes the protonated ion-pair complex formed by the in-situ generation of hydrogen bromide and the polar modifier, which, in conjunction with the polyether stabilizer, constructs a sterically hindered shielding structure at positions 4 and 5 of the substrate molecule. This invention forces the electrophilic substitution pathway to be directed towards position 6 of the substrate molecule, overcoming the bottleneck of extremely low positioning accuracy in passivated aromatic ring systems, transforming disordered isomers into a single dominant isomer, thereby reducing separation energy consumption.

The application discloses an absorption-delivery system for flue gas carbon dioxide capture, which is composed of a hydrophobic high-boiling point hydrophilic absorbent with a very high absorption rate and a high cycle load, and is used for absorbing and delivering carbon dioxide; the absorption-delivery process is that the hydrophobic absorbent directly contacts the flue gas, quickly absorbs CO2, and then reacts to generate a product, then the hydrophobic absorbent contacts the hydrophilic absorbent, the CO2 molecules in the product are delivered to the hydrophilic absorbent by using the strong interaction between the hydrophilic absorbent and the CO2 molecules or the strong proton acceptor characteristics of the hydrophilic absorbent, so that the hydrophobic absorbent is released and reduced, and then contacts the flue gas again to absorb CO2, thereby realizing the recycling of the absorbent. Compared with traditional hydrophilic absorbents, the CO2 absorption-delivery system has the advantages of a fast absorption rate, a low regeneration energy consumption and long-term stability.

A composition usable for removing biofilm and necrotic or infected tissue from a skin lesion, comprising ethanesulfonic acid or 1-propanesulfonic acid and a proton acceptor. The proton acceptor is selected from the group consisting of dimethyl sulfoxide, silicon dioxide, tetraethoxysilane, and mixtures thereof. This composition can be prepared in gel form.

The present invention further relates to a composition comprising methanesulfonic acid and a non-aqueous proton acceptor for use in a method for the treatment and management of one or more of fistula, pilonidal sinus, herpes labialis, pyogenic granuloma, fungal nail infection and onicocriptosis.