The invention discloses a multifunctional clamping device for stress test, and belongs to the field of lossless X ray analysis and detection. The device comprises assemblies including an upper positioning piece, a chuck, a lower positioning piece, a support and a base plate, the upper and lower positioning pieces are used for limiting and positioning, the base plate plays a supporting role, and asupport and chuck pair has functions of limiting and supporting. The device can be used in cooperation with sample stages of different types of test instruments, input and output optimal paths of X rays are not shielded during stress test, and the sample clamping stability, the test point switching efficiency, the optical path adaptability and the repeated positioning accuracy are improved in theresidual stress test process via the X ray method due to cooperation of the assemblies in the supporting, limiting and positioning aspects. The device can be used in cooperation with a stress meter toenhance the versatility, and is suitable for stress test of samples in different appearances including cylinder, prism, cuboid, sphere and casing.